Forteo vs. Tymlos

Posted by suze317 @suze317, Oct 17, 2018

I have to make a decision on Forteo vs. Tymlos and am not sure what to choose. Forteo has been around a lot longer, but has to be refrigerated. Tymlos only around 1 1/2 years but is shelf stable and seems to have less side effects and less issues with calcium. Can anyone offer their perspective? Thank you!

@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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You have to go every day to the doctor for a shot?

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@progolfer

You have to go every day to the doctor for a shot?

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No, you don't have to. You keep the preloaded injections at home. You learn how to use them from a nurse and inject yourself daily. It's a pre-loaded "syringe", for lack of a better word. My understanding is, it's similar to a preloaded insulin injection. I haven't started using it yet, in a week or so I hope to. As soon as it can be arranged I'm going forward.

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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I give my injection at night, seems easier than as part of a morning rush. And my bedtime is more consistent. But for Forteo, which is similar to Tymlos, this study showed a significantly greater response in the lumbar spine when injections were in the morning. Has anyone heard more about this?
"A 12-month morning teriparatide (TPTD) administration resulted in a larger increase in the lumbar spine bone mineral density (BMD) than the evening application. The results indicate that the response of bone cells to teriparatide treatment depends on dosing time." "After 12 months, the lumbar spine BMD grew markedly (p 

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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Hi @betterbones,

I merged your post about "Morning better results for Forteo/Tymlos time of injection-" with this discussion, so that you could reconnect with the members who are part of this conversation.
Here's a link to the article that you've mentioned regarding timing of Forteo injections: https://www.ncbi.nlm.nih.gov/pubmed/22426952

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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Thank you, interesting and important information!

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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I am just joining this group- trying to decide between Forteo and Tymlos. Tymlos has not been on the market long whereas Forteo has been on for 16 years. Forteo has to be refrigerated (inconvenient) and Tymlos doesn't. I'm a little worried about taking a brand new drug. Can anyone offer some perspective? I'm 56 years old with OP in spine -3.3, neck -2.3. Thank you so much.

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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I'm 56 with Osteoporosis and am trying to choose between Forteo and Tymlos for injectible. Forteo has been around so much longer (16 years vs. 1 1/2 for Tymlos) but I don't like the inconvenience of having to refrigerate it. Can anyone offer a perspective? Many thanks!

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@leacy

I’m 59, with osteoporosis, primarily in my spine, 3.4 t-score in spots. I’ll begin a daily injectable soon, it’s called Tymlos. If I understand correctly, it’s the newest version of daily injectable. Does anyone have any experience with this med? The results for other daily injectables sound good. Side effects?

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I replied on another thread. More information– even once you receive insurance approval. To use the drug, you will need to have a training session. I think an in person one is good because the trainer can see your body type, and give you tips accordingly.

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Hello- I am new on this discussion as of today. I needed to stop Fosamax because of horrible upper stomach cramps, throat spasms, etc. I can't take any other pill forms-I have tried the once a month pill (forgot the name). I have broken bones so I really need something. I also stopped going to a rheumatologist because I can never get an appointment when I needed one so I'll use my pcp. Any suggestions? I'm petrified of the shots' side effects. Thank you

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Ask about Reclast. It’s a once a year infusion.

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Oh!! If you get side-effects how long do they last?@ bonnie

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@merpreb

Oh!! If you get side-effects how long do they last?@ bonnie

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I fortunately have never had any side effects. I’ve had the infusion for six years, then you need to take a “vacation” from it. It stays in your system for a long time. The last two years I’ve not had any infusions.

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