Esketamine Therapy for Treatment Resistant Depression: Experiences?

Posted by intheprocess @intheprocess, Aug 22, 2018

Hi, I am new. I have PTSD and treatment resistant depression. As a result, I am participating in a clinical study. I receive nasal spray esketamine. .

Interested in more discussions like this? Go to the Depression & Anxiety Support Group.

Lisa Lucier, Moderator | @lisalucier | 4 days ago

In reply to @ceciford "Refractory depression, tried 1 series of ketamine, did not help. Has tried esketamine nasal spraywith success?" + (show)

@ceciford - I moved your post here so you could chat with others who've been talking about esketamine treatment over many years:

- Esketamine Therapy for Treatment Resistant Depression: Experiences? https://connect.mayoclinic.org/discussion/esketamine/

If you are replying by email, click on VIEW & REPLY so that you will be brought to the new discussion. I suggest reading through and jumping in where you feel comfortable.

Fellow members such as @prn2016 @audriana @clutch intheprocess @intheprocess and others may have ideas on dealing with refractory depression and may have input on use of esketamine nasal spray. @jimhd also may have thoughts for you.

Glad you also connected with @naturegirl5.

What does your doctor who had you on ketamine suggest you do next?

ashleyharris728 | @ashleyharris728 | 3 days ago

In reply to @ceciford "Refractory depression, tried 1 series of ketamine, did not help. Has tried esketamine nasal spraywith success?" + (show)

@ceciford how many treatments were in your series? I’m assuming you are talking about IV ketamine?

I don’t want to discourage you from trying anything that could help, but from what I have heard, if you don’t respond at all to IV, you aren’t likely to respond to other forms of ketamine. Definitely ask your prescribing psychiatrist though.

I’ve only done IV ketamine and I am considered a partial responder. It really helps but not “all the way”.

Wishing you luck on your journey to find something that helps!