Posted by grandmaR @grandmar, Mar 4, 2019

Hi All!
I just got this from AARP. It is part of an article that speaks to how some drugs might cause or attribute to depression.

Know the top ten
These Rx medications are among the most commonly prescribed drugs that can cause depression in adults, according to the JAMA study.
Beta-blockers to treat high blood pressure such as metoprolol, atenolol, enalapril, and quinapril.
Anti-anxiety medications such as alprazolam (Xanax and generic), clonazepam (Klonopin and generic), diazepam (Valium and generic) and lorazepam (Ativan and generic) as well as the sedative zolpidem (Ambien and generic).
Opioids such as hydrocodone (Norco, Vicodin, Lorcet and generic), tramadol (Ultram, ConZip and generic).
Corticosteroids such as cortisone, hydrocortisone or prednisone, which are used to treat a variety of conditions including asthma, lupus and rashes.
Over-the-counter proton pump inhibitors omeprazole (Prilosec, Zegerid and generic) and esomeprazole (Nexium and generic) as well as over-the-counter antacids ranitidine (Zantac and generic) and famotidine (Pepcid and generic).
Certain allergy and asthma medications. The over-the-counter allergy medication cetirizine (Zyrtec and generic) has been linked to depression, as has another type of drug, montelukast (Singulair), which is often used to treat people with allergic asthma.
Anticonvulsant medications such as gabapentin (Neurontin and generic) and topiramate (Topamax and generic).
Amitriptyline to treat nerve pain and prevent migraine headaches.
Hormonal drugs. Estradiol (Delestrogen, Elestrin, EstroGel and generic), commonly used to treat menopausal symptoms and finasteride (Proscar, Propecia and generic), a medication used to treat an enlarged prostate and/or hair loss in men.

The article advises us to keep a close eye on our moods and behaviors and to report changes.
They also stated that the older we get, the better the chance of this happening.

Ronnie (GRANDMAr)

Interested in more discussions like this? Go to the Depression & Anxiety group.

@grandmar – Thank you for posting this. This valuable information for all of us!


@grandmar – Thank you for posting this. This valuable information for all of us!

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You are more than welcome!!


I am fortunate, I suppose. I have dysthymia, and have taken, and am taking, a representative number of these medications. To be fair, the dysthymia predates the medications, but this is good information for those looking for a probable cause. Research can be daunting.

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