Did PAXLOVID also relieve your arthritis and autoimmune symptoms?

Thanks for this! My arthritis symptoms are completely gone as I am on day 4 of taking this drug.

Yes! I am so glad to see this addressed. I was also on dexamethazone (steroid) which I was wondering if that was the reason also.
I remember when covid first came out and I was worried because I was allergic to one of the meds used.
It had been given to me for PsA .
I have had so many bouts of sepsis and covid through Remecade use I am getting desperate for a new treatment. IVIG has also been discussed. I am treated with infusion. Get sick. Recover and usually get another infusion weeks late or a month. Pain is getting so bad. Got Covid and had a pack of 2 paxlovid with one other med in the pack. My pain almost disappeared for 3 weeks now. I am going to my rheumatologist tomorrow. I wish I could take it once a month or every couple months seriously. My pain medication use is almost cut in half. I would forget to take it!

I think I already replied. Not sure I was in the right place. But yes I have had a significant reduction in pain after paxlovid and dexamethason steroids . Fatigue is the same but possibly due to de conditioning . 3 weeks out my pain is still better.
I see my rheumatologist tomorrow. Any suggestions are appreciated.

@annewoodmayo I had a similar experience. I took a 5 day course of Paxlovid and experienced significant relief of joint pain and fatigue (I’ve been diagnosed with psoriatic arthritis or rheumatoid arthritis). Aside from the terrible taste in my mouth it was amazing! The relief lasted until about 4 days after stopping treatment. I’ve since been researching the connection but have found very little so I was glad to come across your post.

I am 73 old male in relatively good health until Aug 2022 when I tested positive for COVID. I was able to receive the bebtelovimab monoclonal antibodies infusion within 2 days. Recovered from COVID in 2-3 days with only some nausea and mild fever. In mid Sep 2022, however, I had a sudden onset of arthritis in ankles / feet. Has progressed up into legs / hips and hands / wrists. Most pain / discomfort happening at night. Morning stiffness in legs. Ibrupofen helps somewhat but low dose prednisone has been the most effective in relieving most symptoms. I test negative for RA. I do show an increased level of inflammation. After reading some of the comments concerning Paxlovid and the reduction of arthritis symptoms, I approached my doctor on the subject and he did write me a prescription for Paxlovid. I went off the prednisone and started the 5 day treatment. Looking good at first, but by day 4 I'm back to pain and stiffness at night. So in my case, the Paxlovid did not relieve my arthritis symptoms. Back on the low dose prednisone.

I had the same experience. Send an email to Pfizer. They actually called me and wanted to know more about how my arthritis symptoms disappeared while taking Paxlovid. They asked me to reach out to others who also experienced this so please contact them!

So over 2 years ago I had a Covid vaccine I self diagnosed as neuropathy in my feet with the pins and needles and pains I went to the podiatrist and he said it was plantar fasciitis. june went to a foot surgeon and had an MRI and he said it was a tumor in my foot he took the tumor out did three other procedures clipping this in that and all the same symptoms were there. December got Covid lasting 3 weeks and the paxlovid took the pins and needles away
but did not take away the thick soul feeling like it's being stretched and pains around the perimeter and severe pain drilled into my heel on occasions, now a month later it’s reoccurring. I don’t know who to turn to, but I have been in agony for over 2 years my PCP xrayed my back and thinks that this condition in my feet is connected to my back, I have no pain in my back but I indicated that since Paxlovid helped it must be something viral … what doctor should i go to i am 68 have Medicare plan F

I have been considering trying paxlovid after reading all of your comments. My tendon/joint problems began after a fever in March 2022. They have been getting progressively worse since then and I have tried Methotrexate, meloxicam, celebrex, Humira, Otezla, and Rinvoq. The only thing that works is prednisone. I am currently taking 8mg of methylprednisone daily. I still have manageable pain, but this is so much better. I mentioned to my rheumatologist the paxlovid thing and she seemed to ignore my comment. She is starting me on Cosentyx when the insurance approves it. Fingers crossed for some relief. This virus has altered my life completely.

Welcome @katiewall7, I'm sorry you haven't found any relief for your foot pain yet. I don't have pain with my neuropathy just some numbness in the feet but I've often thought part of my problem originates in my lower back where I do have some aches but not pain from degenerative arthritis. This article discusses possible causes of foot pain and might be helpful:
--- What Causes Nerve Pain in the Foot?: https://www.verywellhealth.com/nerve-problems-that-cause-foot-pain-1337741

If your PCP thinks the pain might be connected with your back, you might want to ask if you can get a referral to a neurologist to check for neuropathy pain. Have you discussed seeking a another opinion with your PCP?

Paxlovid has helped me get rid of my joint and muscle pains associated with LC. I don’t have an autoimmune disease (although I keep getting tested to see because I’ve been presenting with similar symptoms). And viruses can cause autoimmune diseases.

Seeing an infectious disease doctor who specializes in treating chronic fatigue syndromes, which are post viral conditions, would be who could help those who want to explore this path of virus originated autoimmune and post viral conditions.
I think you’re onto something there and I think someday medicine will have answers that show giving patients cocktails of antivirals, antimicrobials to clear under the radar viral loads that cause all kinds of symptoms will be the cure needed to stop autoimmune and other diseases, like long COVID.