Desvenlafaxine (Pristiq) How does, did it work for you?

Posted by steve1960 @steve1960, Mar 12, 2019

I've recently been prescribed Pristiq (50mg) after trying Citalopram (20mg). On the Citalopram my mood improved slightly - felt kind of numb emotionally, but physically I felt horrible. Headache, anxious, pounding heart, constantly hungry, didn't sleep well, felt as if I had been poisoned, just overall blah. I haven't started taking the Pristiq as I understand it's more difficult to stop and I dread the potential side effects. I was diagnosed with clinical depression in my early twenties and am now in my late fifties. I have tried Paxil, Welbutrin, and Prozac in the past. Over the past six years, my depression has been worse than ever. I'm interested in hearing from folks that have experience taking Pristiq. Thanks in advance.

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I've been taking it for 10 years. I've taken probably 15 different things over 45 years. I also take Lamictal for mood. I think It too is good. As I was told years ago, there is nothing magic about pills nor what the doctor says, but it all offers a lot of help to get us through the life we live. 74 now and still have bad days and anxiety. But Pristiq is doing pretty well. Hope you get better.

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@mdavis1240

Hi all. I'm new to the group and have suffered from GAD and depression since I was a little kid. My doctor recommended Pristiq. I started on 50 mg for a week and then she upped it to 100 mg. I've been on 100 mg for 10 days. I wish I could say I'm feeling better but I'm not. Can anybody give life experiences with this drug?

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10 years for my taking Pristiq 50, 100, back to 50. I also take Lamictal for mood. I have taken at least 15 things since I was diagnosed at 28 and I am now 74. Doctor said he has no magic pill, but they do help a lot. The more I stay busy, physically I do much better too.

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@larrypains

Does your experience say it may still work?

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I took the brand name Pristiq in 2012-2014. For me, it was a good drug for depression and basically no side effects. I had significant weight gain on Lexapro but not Pristiq. I can't say a generic is as good, sometimes they are not. I did have to use Prozac as a bridge to taper off since Pristiq is an extended release and hard to taper.

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