Decided on nerve sparing surgery

Posted by ginger38314 @ginger38314, Sep 30 8:23am

I decided to go the surgery route, if it wasn't for the high decipher score I would have chose sbrt, so they will call me within a week to sceduled, thanks everyone for you comments.

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ginger38314 | @ginger38314 | Oct 5 8:50am

In reply to @ezupcic "@ginger38314 just curious if you met with radiation oncologists at OHSU and what that was like?" + (show)

Had plenty of time to discuss my concerns and he was personable and
listened to me , one thing I forgot to mention if you will remove lymph
nodes during procedure.

ginger38314 | @ginger38314 | Oct 5 8:53am

In reply to @ezupcic "@ginger38314 just curious if you met with radiation oncologists at OHSU and what that was like?" + (show)

I'm sorry you meant Dr Hung he also was informative and answered my
concerns and I had several concerns afterwards and got back to me right
away and addressed those issues.

ezupcic | @ezupcic | Oct 20 12:56pm

In reply to @ginger38314 "I'm sorry you meant Dr Hung he also was informative and answered my concerns and I..." + (show)

@ginger38314 you mentioned that you had a low volume of cancer. Was it mostly 3+3 ?

ginger38314 | @ginger38314 | 6 days ago

In reply to @ezupcic "@ginger38314 you mentioned that you had a low volume of cancer. Was it mostly 3+3 ?" + (show)

Low volume meaning 2 cores 3+4 @ 10% component of 4 and .8cm lesion t1c.

ezupcic | @ezupcic | 6 days ago

In reply to @ginger38314 "Low volume meaning 2 cores 3+4 @ 10% component of 4 and .8cm lesion t1c." + (show)

@ginger38314 were you classified as "favorable intermediate 3+4" or unfavorable intermediate". I'm still confused by how somewhat favorable pathology can still lead to a high decipher score. But apparently, it can. Decipher in my case will be important as well in terms of treatment.

jim18 | @jim18 | 6 days ago

In reply to @ezupcic "@ginger38314 were you classified as "favorable intermediate 3+4" or unfavorable intermediate". I'm still confused by how..." + (show)

@ezupcic Pathology is looking at the cells in the tumor. Decipher is looking at the genes in the tumor. If they find BRCA1/2, PTEN, or other genes with high cancer risk that will result in a high Decipher score even if the current disease does not reflect advanced pathology.

surftohealth88 | @surftohealth88 | 6 days ago

In reply to @jim18 "@ezupcic Pathology is looking at the cells in the tumor. Decipher is looking at the genes..." + (show)

@jim18

Decipher actually measures RNA expression of 22 specific genes. Those genes produce so called biomarkers that control cancer growth, signaling, metabolism of cells etc etc. The more mutations are present in THOSE 22 genes, the more is cancer aggressive. So it is different than any other test - somatic and germ-line look for BRCA etc. NOT Decipher.

surftohealth88 | @surftohealth88 | 6 days ago

In reply to @ezupcic "@ginger38314 were you classified as "favorable intermediate 3+4" or unfavorable intermediate". I'm still confused by how..." + (show)

@ezupcic

Pathology looks ate the shape, size and distribution of cells and Decipher measures genetic markers which are actually molecules (can not be seen under the microscope).

ginger38314 | @ginger38314 | 6 days ago

In reply to @ezupcic "@ginger38314 were you classified as "favorable intermediate 3+4" or unfavorable intermediate". I'm still confused by how..." + (show)

I was 3+4 favorable intermediate but high decipher which says I should get
treated in the near future and rules out AS even though I have only 2 cores
positive and a .8cm lesion and pet scan clear.