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Decided on nerve sparing surgery
Prostate Cancer | Last Active: Oct 23 3:26pm | Replies (69)Comment receiving replies
@ezupcic Pathology is looking at the cells in the tumor. Decipher is looking at the genes in the tumor. If they find BRCA1/2, PTEN, or other genes with high cancer risk that will result in a high Decipher score even if the current disease does not reflect advanced pathology.
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@jim18
Decipher actually measures RNA expression of 22 specific genes. Those genes produce so called biomarkers that control cancer growth, signaling, metabolism of cells etc etc. The more mutations are present in THOSE 22 genes, the more is cancer aggressive. So it is different than any other test - somatic and germ-line look for BRCA etc. NOT Decipher.