Anyone else on Daraxonrasib (RMC-6236)?

Posted by howleegirl @howleegirl, May 8 5:59am

Waiting for the approval for my husband to start daraxonrasib. (the new and exciting drug just fast tracked by the FDA) Doc says he's a great candidate for this drug. Anyone else on this? I know about the awful rash you get from seeing the senator on TV. Doc has also styopped all treatment since April 11th. THAT kinda scares me?

Interested in more discussions like this? Go to the Pancreatic Cancer Support Group.

witchypooy | @witchypooy | 11 hours ago

In reply to @mcharlesfrancis "I have pancreatic cancer myself, but I have never taken daraxonrasib. My initial treatment was the..." + (show)

i have never heard of radiation as a treatment for pancreatic cancer? Hubby took the chemo, but was recommended because of his age (80) to do just an every other week treatment, as studies have shown this modified schedule keeps quality of life up in seniors while making very little change to life span. Of course there is no cure for pancreatic cancer, you take the chemo as long as you can stand it or until your quality of life deminishes. My hubby has had 33 treatment. But never was it ever suggested he have "radiation" as well, perhaps you are younger or it has spread to where radiation makes sense. Anyway, my Hubby is now on the "pill" and has gotten off his chemo . It has only been 3 weeks so we have no data to see any change, other than quality of life, and frankly, his fatigue is worse on the pill, so far all other symptoms being minimal. He has been lucky, but is the "pill" right for him? the next CT will iprobably give us some info on that, but I am beginning to believe that given our good experience on chemo, holding his cancer off to a very slow but steady spread, to be a good thing, and the pill may not be as good for him. Each patient is different. Good luck with your decision, but please drop a line to me regarding the radiation you have undergone. I am very interested in that avenue that our doctor has continually told us is not available. write thanks

azsunshine7 | @azsunshine7 | 2 hours ago

Check this clinical trial out
https://clinicaltrials.gov/study/NCT07491445
This is a global, randomized, open-label, Phase 3 study designed to evaluate whether treatment with daraxonrasib monotherapy or daraxonrasib plus gemcitabine and nab-paclitaxel will improve progression-free survival and/or overall survival compared with standard gemcitabine and nab-paclitaxel when given as first-line treatment in patients with metastatic pancreatic adenocarcinoma.