Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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Profile picture for calofmichigan @calofmichigan

@nanniesue4
I’ve been on Cymbalta for a few decades. For me, it helps with the pain and depression, but I noticed I feel very flat emotionally most of the time.
I’m so sorry for your multiple surgeries and problems. It’s clear that cutting further may not be the answer.

After multiple spine surgeries and the generalized pain from psoriatic arthritis, I’ve decided to pursue other modalities to deal with it: massage, visits with a pain psychologist, physical therapy, walking and exercise as much as the pain will allow, and surrounding myself with understanding friends and family. I hope you will find the answers for your disability. It doesn’t mean I’m pain free. It just means I’m heading in another direction. Every time a surgeon cuts on me, I feel like I’m laden with more problems than before. Enough already.

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@calofmichigan FYI - My daughter was diagnosed with psoriatic arthritis last year. She takes Otezla and says it's night and day. She also says she didn't realize how much pain she was in until she took it and the pain abated.

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I was taking it for depression and pain caused by leukemia. It made me sweat profusely whenever I expended any energy. I made a personal decision to stop cymbalta and all my other cancer drugs. I slowly cut back on the cymbalta for only 2 weeks, then down to none at all. Took a couple of months to get rid of the sweating and weird dreams. It’s been 4 months now and I’m finally feeling myself again. It was only my second experience with a drug for depression (first one was Effexor 20 years ago) and I say NEVER AGAIN. It did not help with leukemia pain but was effective for calming me. Just not worth the side effects. Gook luck to you.

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Profile picture for captoblivious @captoblivious

@calofmichigan FYI - My daughter was diagnosed with psoriatic arthritis last year. She takes Otezla and says it's night and day. She also says she didn't realize how much pain she was in until she took it and the pain abated.

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@captoblivious
Thanks so much for that. I’ve been taking Inflectra infusions which hasn’t helped much. I’ll ask my rheumatologist about Otezla. It’s so discouraging.

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