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Considering no meds and trying diet, exercise and supplements

Posted by osteocurious @osteocurious, Nov 20, 2025

Hello. I have read soooooo much about both. Meds vs naturally increasing bone mass density. Please if anyone has successfully bypassed the med route - what did you do? How long did it take? Are you pleased with your increase? I am strongly considering no meds as I am on a cocktail already for epilepsy - which decreases bone density! I dont need more despair from possible brittle bones from meds. Thank you for any hope.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

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lindamaegirl | @lindamaegirl | 6 hours ago
In reply to @sueinmn "@maggieb246 Here are a couple links from Google Scholar to studies, the first is of cissus..." + (show)
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@maggieb246 Here are a couple links from Google Scholar to studies, the first is of cissus quadrengularis. It was a review of published research, and their take was the total samples were 354 people, and most of the studies has indication of bias:
https://link.springer.com/article/10.1186/s12906-025-04995-8
The second was a review of 50 years of studies of dalbergia sissoo (common names sheesham or Indian Rosewood). A handful of those studies explored the osteogenic (bone enhancing) properties, and only one of these, involved humans (30women for 12 months)
https://academic.oup.com/jpp/article/75/4/482/7057817
Here is a link to that study where women were given 300 MG of the herb twice a day for 12 months, along with daily calcium and vitamin D. There was no control group:
https://journals.lww.com/jomh/fulltext/2019/10010/a_clinical_study_of_a_standardized_extract_of.8.aspx
Given the extremely small samples, the sparsely of carefully constucted studies, and the huge price of the supplement, I personally would pass.

We also do not know the potential side effects of these unregulated supplements. Keep in mind that Osteoporosis medications are subject to 3 phases of regulated testing and documentation of all side effects. Products like Osteofrax have not been subjected to any of this.

What is your hesitation to trying drugs from your doctor?

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@sueinmn have you read the black box warnings?????

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Sue, Volunteer Mentor | @sueinmn | 3 hours ago
In reply to @lostbone9 "Hi, I have been dancing around Osteofrax - not sure of what it is and trying..." + (show)
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Hi, I have been dancing around Osteofrax - not sure of what it is and trying to find supplements that work. I am now testing my vitamins in white wine vinegar heating to 180 degrees to try to imitate my stomach and trying to find out if my body a. assimilates it into my body, or b. do I pee it all out and there is no effect on my body as I cannot assimilate. More will be revealed as I need to buy vinegar tomorrow as I do have white only red and it is not effective. Osteofrax gives no information or reviews there are 4 star, 3 star and 1 star reviews but none are revealed. He the "BoneCoach" is having a free seminar tomorrow. I am trying to find a good Calcium Vitamin and B12 vitamin. More to come. Marie Torrisi

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@lostbone9 Can you explain this test, and where you learned about it?

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njx58 | @njx58 | 3 hours ago
In reply to @lindamaegirl "@sueinmn have you read the black box warnings?????" + (show)
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@sueinmn have you read the black box warnings?????

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@lindamaegirl Forteo and Tymlos black box warnings were removed a few years ago.

Prolia has one re: severe low blood calcium for people with kidney disease.

Evenity does have one re: cardiovascular events.

Reclast has warnings (not black box) re: renal impairment, so not recommended for anyone with kidney issues.

Fosamax has warnings for osteonecrosis and atypical femur fractures, both associated with long-term use.

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