I am going to be starting Clofazimine along with the big three as one strain of MAC I have is resistant to Azithromyacin. I am as wondering if anyone has had experience with this drug?
Hi
I’ve been on the same combo since the summer. No problems with clofazimine- just be sure to cover up from the sun as it will darken your skin all the more if you don’t .( sunscreen, hat , long sleeves, gloves-it darkens age spots). Also with being on azithromycin too, you should get an EKG after a month or so to make sure no QTc prolongation.
Good luck with the treatment!
Hi
I’ve been on the same combo since the summer. No problems with clofazimine- just be sure to cover up from the sun as it will darken your skin all the more if you don’t .( sunscreen, hat , long sleeves, gloves-it darkens age spots). Also with being on azithromycin too, you should get an EKG after a month or so to make sure no QTc prolongation.
Good luck with the treatment!
Thank you. I had bad reaction to Arikayce so I have been worried about this, even though the side effects are different. I have been getting monthly EKG and blood work since October.
Hi
I’ve been on the same combo since the summer. No problems with clofazimine- just be sure to cover up from the sun as it will darken your skin all the more if you don’t .( sunscreen, hat , long sleeves, gloves-it darkens age spots). Also with being on azithromycin too, you should get an EKG after a month or so to make sure no QTc prolongation.
Good luck with the treatment!
Hi
I’ve been on the same combo since the summer. No problems with clofazimine- just be sure to cover up from the sun as it will darken your skin all the more if you don’t .( sunscreen, hat , long sleeves, gloves-it darkens age spots). Also with being on azithromycin too, you should get an EKG after a month or so to make sure no QTc prolongation.
Good luck with the treatment!
@garry, the QT interval is a measurement made on an electrocardiogram used to assess some of the electrical properties of the heart. QT prolongation happens when the heart muscle takes longer than normal to recharge between beats. It is an electrical disturbance which can be seen on an electrocardiogram (ECG). Excessive QT prolongation can trigger tachycardia – a heart rate over 100 beats per minute.
@dulwich may be able to explain more and his experience with QTc prolongation and azithromycin.
Thank you for responding. I have been on the clofazamine now for about 6 weeks. I am pleased that the side effects are relatively benign. Mostly for me it is digestive issues. Working hard to gain some weight. Hoping this will get rid of the resistant strain of MAC.
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Hi
I’ve been on the same combo since the summer. No problems with clofazimine- just be sure to cover up from the sun as it will darken your skin all the more if you don’t .( sunscreen, hat , long sleeves, gloves-it darkens age spots). Also with being on azithromycin too, you should get an EKG after a month or so to make sure no QTc prolongation.
Good luck with the treatment!
Thank you. I had bad reaction to Arikayce so I have been worried about this, even though the side effects are different. I have been getting monthly EKG and blood work since October.
Thank you
What is QTc prolongation
@garry, the QT interval is a measurement made on an electrocardiogram used to assess some of the electrical properties of the heart. QT prolongation happens when the heart muscle takes longer than normal to recharge between beats. It is an electrical disturbance which can be seen on an electrocardiogram (ECG). Excessive QT prolongation can trigger tachycardia – a heart rate over 100 beats per minute.
@dulwich may be able to explain more and his experience with QTc prolongation and azithromycin.
They said I had extra beats. Not to worry lots of people have that they said.Thanks for the info.
I was on Clofezamine for over a year back in 2016-17. No issues except dry eyes and a nice tan.
Thank you for responding. I have been on the clofazamine now for about 6 weeks. I am pleased that the side effects are relatively benign. Mostly for me it is digestive issues. Working hard to gain some weight. Hoping this will get rid of the resistant strain of MAC.