CBD oil and depression/anxiety

Posted by lalyfa @lalyfa, Feb 24, 2018

I am curious to know if anyone has had success with CBD or Hemp oil helping with depression/anxiety? I’ve been reading a lot about it and am curious.
I’ve been reading about this and am very interested but would like thoughts/opinions from anyone who has actually tried it or knows someone who has. TIA

Thank you,
Laura

Hi I am new here. First for those that don't know…..
* CBD oil with "NO" THC = is LEGAL in all 50 states (Hemp part of the plant) can't get high
* CBD oil with THC = check your state (Marijuana part of the plant) you DO get high
(THC stands for psychoactive Tetrahydrocannabinol)

I tried to read ALL of the posts and I still didn't find my answer.

"I want to know if there is anyone that has come off of an anti-depressant 100% for anxiety and replaced it CBD oil with NO THC?" And does it work. I don't want to take Effexor anymore. I want to be free of that med! The side effects are horrendous. I am a recovering addict so I don't want to take any benzo's or CBD oil with the THC in it. Maybe it's too new to have any statics on it yet.

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@stressedmesseddepressed

Glad you're off that stuff and sorry to hear about the hell of cold turkey on that stuff. I've had a taste of that horror missing doses of a benzo, clonazepam, and now tapering slowly over 5 months. The other things – weed psychological addiction, sugar, caffeine, gonna white knuckle the weed as I'm out soon and saving to take the bar exam. I'm going to try using CBD oil as I heard it's effective at reducing anxiety, lifting mood, and so on. Thank you for sharing and wishing you, too, and us all, good health and peace. Will ask my pharmacist about expected withdrawal. Thank you!

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@stressedmesseddepressed The CBD oil does help me some with anxiety and depression. At least there are not those extreme withdrawals as with the pharm's mentioned. Sevre enough I would not want to go through thus again. Stay tough-A bar exam requires focus. etc.

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I was semi-wrong. I got better clarification:

CBD oil is found in two common forms:

1) CBD oil from isolate – the CBD is isolated from other cannabinoids and the oil contains zero THC.
2) Full Spectrum CBD oil – oil contains CBD plus other cannabinoids, including very trace amounts of THC (.03% or less)

Benefits of CBD isolate – legal and isn't looked for in standard drug tests.

Benefits of Full Spectrum CBD – All cannabinoids, including CBD, are generally considered more effective when combined. This is called the "entourage effect". Trace amounts of THC (small enough to not be psychoactive) is known to boost the effectiveness of CBD, therefore Full Spectrum CBD products are often considered superior. However, some people cannot have any THC in their systems whatsoever (employment/drug testing) and in those cases I do not recommend full spectrum products because of the few cases I've seen of trace amount of THC being detected in drug tests.

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@ecjames71

I was semi-wrong. I got better clarification:

CBD oil is found in two common forms:

1) CBD oil from isolate – the CBD is isolated from other cannabinoids and the oil contains zero THC.
2) Full Spectrum CBD oil – oil contains CBD plus other cannabinoids, including very trace amounts of THC (.03% or less)

Benefits of CBD isolate – legal and isn't looked for in standard drug tests.

Benefits of Full Spectrum CBD – All cannabinoids, including CBD, are generally considered more effective when combined. This is called the "entourage effect". Trace amounts of THC (small enough to not be psychoactive) is known to boost the effectiveness of CBD, therefore Full Spectrum CBD products are often considered superior. However, some people cannot have any THC in their systems whatsoever (employment/drug testing) and in those cases I do not recommend full spectrum products because of the few cases I've seen of trace amount of THC being detected in drug tests.

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@ecjames71 In a nutshell explanation-thanks. I can say I do NOT get a high with full spectrum CBD oil. I have not ever smoked pot either and with so small of an amount THC it would seem unlikely. Since you stated you are a recovering addict I can understand your not wanting the full spectrum CBD as it may affect you or anyone else with addictive issues. Also, as I have mentioned at different times we are not all wired the same.

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@gailb

@parus

I have copied Colleen Young's posted links to information about CBD use for anxiety, PTSD, and depression. The articles are excellent and encouraging. If you're willing to do your own experiment, and it's legal where you live, you may want to try CBD as an alternative to the medications you have previously taken. One article mentioned a research using 400 ml of CBD per day per person. That's a huge dose! I use a CBD product that is .75 ml CBD, and .25 mL THC per dose. I use 3-4 doses at that level twice a day, and it works very well for me.

"While there is promising evidence that CBD may help anxiety, the jury is still out. Here are some articles to help you when discussing with your health providers or considering what you need to know when purchasing any unregulated substance:
– Does CBD Really Work For Anxiety? (HuffPost) https://www.huffingtonpost.ca/entry/does-cbd-work-for-anxiety_us_5af4924ce4b00d7e4c18a6ac
– Anxiety Relief Without The High? New Studies On CBD, A Cannabis Extract (NPR) https://www.npr.org/sections/health-shots/2018/04/23/604307015/anxiety-relief-without-the-high-new-studies-on-cbd-a-cannabis-extract "

I hope you find some help and relief with this unconventional treatment with CBD.

Gail
Volunteer Mentor

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@gailb I have been having some positive results with the CBD oil with the THC. 400 ml would be a seemingly high dose as I take 2 ml/day dividing it up into 4 doses. It is expensive though. Cannot imagine the cost of 400 ml/day. There are days I do not use as much. I do know I am sleeping better at night!!! Grandkids today so I am now in my grandma happy place. They are so accepting of my limitations.

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@colleenyoung

Recently, discussion in some groups has focused on cannabidiol (CBD), a naturally occurring cannabinoid constituent of cannabis and medical marijuana. With these conversations come several concerns and the need for clarification.

1. Evidence vs usage
To date CBD to treat epilepsy (in children) is the only condition that has some scientific evidence supporting its use in some cases. CBD for pain, anxiety, inflammation and sleep remains as yet scientifically unproven and requires more validated research.

According to this article by NPR (https://n.pr/2HnI1SM), “By one estimate, the CBD industry has doubled in size over the last two years, and is now worth $200 million. But with this popularity the hype may have gotten ahead of the science.”

While there is promise and ongoing research into CBD effectiveness in managing pain, anxiety, inflammation and sleep, the jury is still out. Here are recent articles that help clarify.

– CBD Oil: All the Rage, But Is It Safe & Effective? (WebMD) https://wb.md/2K11QfD
– Does CBD Really Work For Anxiety? (HuffPost) https://bit.ly/2wF1VUs
– Anxiety Relief Without The High? New Studies On CBD, A Cannabis Extract (NPR) https://n.pr/2HnI1SM

2. Industry is unregulated
CBD is not regulated. “Because of the legally murky nature of marijuana, the FDA has not stepped in to regulate products like CBD oil.” States are struggling to put regulations in place. … Meanwhile, a 2017 study led by Bonn-Miller found that nearly 7 of 10 CBD products didn’t contain the amount of marijuana extract promised on the label.” Read more about regulation in this WebMD article (https://wb.md/2KCS4UW).

There are risks associated with medical marijuana CBD. See this post from a Mayo Clinic pharmacist (https://mayocl.in/2KDyip2). People should also consider interactions with other drugs and always discuss the use of CBD with their medical provider and consult with a pharmacist.

3. Concerns about attracting sellers and fraudsters
With the increasing activity related to CBD on Connect comes the unwanted attention of commercial sellers of product and fraudsters. Mayo Clinic Connect’s Terms of Use (https://connect.mayoclinic.org/terms-of-use/) prohibit “any material which … (viii) contains any information, software, or other material of a commercial nature; (ix) contains solicitations or advertisements of any kind; (x) constitutes or contains false or misleading indication of origin or statement of fact…”

Our Moderating team keeps a watchful eye for people with commercial interests posing as members on Connect. If you see posts that contravene the Terms of Use, please report them. Here's how: https://connect.mayoclinic.org/page/about-connect/tab/moderators/

4. Is it legal?
It has often been stated or asked about the legality of CBD in all 50 states. According to this article in Forbes “CBD is not legal in all 50 states (https://bit.ly/2KFY2nV) — even though it is widely available. At best, the law is murky and open to differing interpretations.”

– Is CBD Legal? The Legal Status of CBD in 2018 (Medium) https://bit.ly/2EEuwYB
– The legal status of cannabis (marijuana) and cannabidiol (CBD) under U.S. law (Elsevier 2017) https://bit.ly/2tk68Zu
– State Medical Marijuana Laws (2018) https://bit.ly/1udxSs4

5. Information from Mayo Clinic
Mayo Clinic provides the following information on medical marijuana https://mayocl.in/2KyrGvp

6. Get informed
Information about the use, efficacy and legality of CBD and medical marijuana is constantly being updated. Do your research. It is advisable to talk with a health care professional if you have questions.

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@colleenyoung I have not mentioned the use of CBD to my healthcare provider as I am uncertain as to how much they actually know. After all the trouble I had getting one to listen about Synthroid and prescribe Armour as to the severe side effects of Synthroid-Mercy, some of these folks can narrow-minded!!!
The CBD has been helping as to anxiety/depression some and it has been worth the try thus far.
Think the FDA will ever approve it on levels? If it should reach the point of requiring a prescription things could become interesting or at least I see the possibility on some levels.

REPLY
@gailb

@lalyfa

Welcome to Mayo Connect. I am a Volunteer Mentor and not a medical professional. As such I can offer the benefit of my personal experience, as can others on this site, but not medical diagnoses nor medical opinions. We strive to help each other with the understanding that we are all different and what works for me may not work for you. I have gotten so much good from participating in Mayo Connect that I love it.

Yes, I have used CBD tincture and CBD Living Water for anxiety. I haven't used it for depression as I already take an antidepressant. It doesn't seem to interfere with my Citalopram.

I decided to try CBD when I was withdrawing from Tramadol, a synthetic opiate I had been taking for pain (with 2 other medications) for over a year. As I began slowly reducing my use, I experienced a lot of anxiety and muscle tremors in my legs especially. I know that using a marijuana medication meant that my pain doctor would not prescribe for me again, but I was getting off the pain medications one by one anyway, so I don't care.

The CBD Living Water was my favorite as it just was like drinking bottled water and was immediately available in my system. Within a few minutes of drinking one serving, my anxiety began reducing. It was so benign that I thought perhaps it was just my own thoughts that were calming me down–my belief that it would help. So, I bought the CBD tincture as kind of a test to see if I reacted the same. The next time I was having withdrawal anxiety I used the CBD Tincture. I didn't realize at that time that it can take up to 2+ hours to have effect when you take the tincture, but that was actually good for my test purposes. My anxiety continued for another hour until slowly the tincture began taking effect. I decided then that the CBD Living Water worked best for my anxiety.

CBD Living Water is expensive at $5.00 per bottle with 2 servings. It has no flavor (the tincture had a sweet weird flavor I didn't like) and is easy to drink. I only used 4 bottles to help me through my withdrawal. I don't use it now, but I will if I have anxiety in the future. I am impressed with how helpful it was in my withdrawal. I think it would help in withdrawal from cigarettes too. I did that 34 years ago though.

Are you willing to share what you're anxiety is about? I had panic and anxiety attacks for years and used Ativan and later Lorazepam for them, especially when I had to fly in planes. About 6 years ago I started taking Citalopram antidepressant, and all my anxiety/panic attacks went away. I only had it again recently during my withdrawal process. I know my relief from anxiety is from the Citalopram. I even did 7 zip lines in Costa Rica a little over a year ago. My flights there, to Panama and back were anxiety free. That has been so incredible for me! I love traveling now.

Please let me know if you have questions,. I also hope others on Mayo Connect will let you know their experiences with CBD and Marijuana as medical alternative treatments.

Gail B
Volunteer Mentor

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This is probably a good idea. I believe there are contraindications with blood thinners.

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A brief update on my progress with the CBD oil. The area I have noticed the improvement with is quality of sleep. Does help to have quality sleep.

REPLY
@gailb

@lalyfa

Welcome to Mayo Connect. I am a Volunteer Mentor and not a medical professional. As such I can offer the benefit of my personal experience, as can others on this site, but not medical diagnoses nor medical opinions. We strive to help each other with the understanding that we are all different and what works for me may not work for you. I have gotten so much good from participating in Mayo Connect that I love it.

Yes, I have used CBD tincture and CBD Living Water for anxiety. I haven't used it for depression as I already take an antidepressant. It doesn't seem to interfere with my Citalopram.

I decided to try CBD when I was withdrawing from Tramadol, a synthetic opiate I had been taking for pain (with 2 other medications) for over a year. As I began slowly reducing my use, I experienced a lot of anxiety and muscle tremors in my legs especially. I know that using a marijuana medication meant that my pain doctor would not prescribe for me again, but I was getting off the pain medications one by one anyway, so I don't care.

The CBD Living Water was my favorite as it just was like drinking bottled water and was immediately available in my system. Within a few minutes of drinking one serving, my anxiety began reducing. It was so benign that I thought perhaps it was just my own thoughts that were calming me down–my belief that it would help. So, I bought the CBD tincture as kind of a test to see if I reacted the same. The next time I was having withdrawal anxiety I used the CBD Tincture. I didn't realize at that time that it can take up to 2+ hours to have effect when you take the tincture, but that was actually good for my test purposes. My anxiety continued for another hour until slowly the tincture began taking effect. I decided then that the CBD Living Water worked best for my anxiety.

CBD Living Water is expensive at $5.00 per bottle with 2 servings. It has no flavor (the tincture had a sweet weird flavor I didn't like) and is easy to drink. I only used 4 bottles to help me through my withdrawal. I don't use it now, but I will if I have anxiety in the future. I am impressed with how helpful it was in my withdrawal. I think it would help in withdrawal from cigarettes too. I did that 34 years ago though.

Are you willing to share what you're anxiety is about? I had panic and anxiety attacks for years and used Ativan and later Lorazepam for them, especially when I had to fly in planes. About 6 years ago I started taking Citalopram antidepressant, and all my anxiety/panic attacks went away. I only had it again recently during my withdrawal process. I know my relief from anxiety is from the Citalopram. I even did 7 zip lines in Costa Rica a little over a year ago. My flights there, to Panama and back were anxiety free. That has been so incredible for me! I love traveling now.

Please let me know if you have questions,. I also hope others on Mayo Connect will let you know their experiences with CBD and Marijuana as medical alternative treatments.

Gail B
Volunteer Mentor

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Gail, where did you get the water and did you need an RX? I'm in Florida and we just legalized but I think only under doctors RX.

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Where can this be purchased and the pricing? I use Charlottes Web Hemp CBD oil and it seems to help with my anxiety

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REPLY
@orangelotus

**Note from the Community Director**
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Please tell me the amount of CBD to use,if you have a brand name and how to access information.

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Orange, please tell

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Yes. I have been on antidepressants for almost 20 years and have had a terrible time with discontinuation symptoms each time I try to stop taking them. Every antidepressant I have taken has given me at least one undesirable side effect so I decided to get my medical marijuana card and try that route. I bought a CBD capsule from Knox Medical called Perla and I cannot believe how well it has been working. I completely stopped Well Turin and am on my 5th day of not taking Cymbalta. I am having brain zaps and dizziness but no anxiety or depression. It’s truly like a miracle. The difference between the CBD I take and what’s in the general market is that it is from the marijuana plant and not the hemp plant. It does not give a high effect. I just noticed that the elephant that weighed on my chest for so many years had gone away about 2 weeks in to taking it. The more I have read about Cymbalta the more furious I have become that my phychiatrist didn’t warm me of all of the side effects and discontinuation effects. I had been on Effexor several years ago and never wanted to go on a drug like that again. I was skeptical of the CBD but was desperate to try something that wasn’t Xanax or addictive to calm my anxiety. Hope my experience helps someone reading and hope I can make it through these awful brain zaps over the next few days. I will never take another antidepressant again!

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@kanne11

Yes. I have been on antidepressants for almost 20 years and have had a terrible time with discontinuation symptoms each time I try to stop taking them. Every antidepressant I have taken has given me at least one undesirable side effect so I decided to get my medical marijuana card and try that route. I bought a CBD capsule from Knox Medical called Perla and I cannot believe how well it has been working. I completely stopped Well Turin and am on my 5th day of not taking Cymbalta. I am having brain zaps and dizziness but no anxiety or depression. It’s truly like a miracle. The difference between the CBD I take and what’s in the general market is that it is from the marijuana plant and not the hemp plant. It does not give a high effect. I just noticed that the elephant that weighed on my chest for so many years had gone away about 2 weeks in to taking it. The more I have read about Cymbalta the more furious I have become that my phychiatrist didn’t warm me of all of the side effects and discontinuation effects. I had been on Effexor several years ago and never wanted to go on a drug like that again. I was skeptical of the CBD but was desperate to try something that wasn’t Xanax or addictive to calm my anxiety. Hope my experience helps someone reading and hope I can make it through these awful brain zaps over the next few days. I will never take another antidepressant again!

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*wellbutrin

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