Catamenial Epilepsy and Progesterone Therapy

Posted by kbredimus @kbredimus, Oct 2, 2018

Hi there,

I was diagnosed with TLE back in May 2018 and have been on Lamictal 100mg/2x daily since then. My seizures have always been focal aware--basically just deja vu or a brain "scramble" building to a surge of tingles/adrenaline--the whole thing lasting about 20 seconds. The Lamictal has reduced the frequency (I used to get them after having alcohol but that has stopped.) However, I still get them every 14 days, immediately preceding ovulation and menstruation. This leads me to believe I have catamenial epilepsy.

I got on birth control (Junel) to suppress my period but this had no effect, possibly because it had estradiol in it? My question is this--would it be beneficial to get on progesterone-only birth control to control these refractory seizures, and if so, would this lower the effectiveness of Lamictal? I know there is a correlation between Lamictal and birth control, the latter reducing the effectiveness of the former. Just trying to find out of progesterone has helped people with the same issue/meds that I have.

Also, does anyone know of a good neuroendocrinologist specializing in catamenial epilepsy? Thanks!

Interested in more discussions like this? Go to the Epilepsy & Seizures Support Group.

Hi Jen (@jennydb)
I do not know much about Catamenial Epilepsy. But, period is a common trigger to seizures in women. I have temporal lobe epilepsy and my menstrual cycle is one of my triggers. I, therefore, take birth control pill so as not to menstruate. I do not know however if a birth control pill is recommended for a girl of just 12 years of age (I am 51 years old), this needs to be checked with her doctor and gynecologist. Is she taking medication for her epilepsy? Have you already been to an epileptologist or neurologist to see the possibilities to control her seizures?
All the best!
Santosha

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