What's your experience wtih Brinsupr (brensocatib)?

@brody89 I’ve been on Brinsupri since November and experienced relief in about 3 weeks. I hope you can get it soon. It’s truly made my life better!! I’m not sure if it’s good for ever lung problem. But it’s definitely a drug for Bronchiestasis.

@scoop thanks for your comments. After stopping Brinsupri for one week, my gums are clearing, blood pressure is dropping and headache has stopped. Since blood pressure is not quite normal yet, I’m reserving judgement as to if and when, to restart with 10 mg. I have some short trips planned soon which I couldn’t take with the side effects I had. Have you or anyone reading this had side effects with 25 mg, but fewer, or none, with the 10ng?

@susie2
I've been on Brinsupri (25 mg) for about 6 weeks now and have noticed an increase in my systolic blood pressure of about 20 points. I'm also experiencing the "jitters", which is an uncomfortable feeling. If it persists, I will ask doctor to decrease dosage to 10 mg.

@pumpkin8088 Thanks for your reply.The fact that you are feeling alot better is a good sign.
It also would be a help on conditon severity and stopping the use of other medications (steriods)which have side effects and are not good for the immune system.Which is also an added bonus.
The 25 mg dose apparently also stops disease progression.
Iam based in Australia but not approved here yet, cant wait for it to be approved.

I have started Brinsupri and wondering what other experiences are with side effects. So far, I see some reduction in coughing and sputum output. I am concerned and interested to know if anyone has experienced any signs of Alopecia. My scalp seems to be experiencing some tingling sensation and some itching.

Oh, that is helpful to know. So it didn't lead to any hair loss? I am currently taking 10 mg and it has reduced the coughing, which is a relief. Thanks for your input. Appreciated 🙂

@tolepainter I have bronchiactasis moderate to severe with psuedonama aerigenosa . I had an exacerbation beginning this year that lead to IV cefepime for 2weeks . Since then I received a vest and waiting on a better nebulizer. Using a store bought one now that isn't very goid . With the 7% sodium inhalation. I have never had a cough ,I just clogged with mucus plugs . I do the pickle plus aeribeka with sodium can get up 1/4 ,cup mucus a day or more. Vest may do a little help use that to. Since ive come off cefipime ive virually have no inflammatory signs as of now , been 3 m. My doctors wanted me on brinsupri right away after the cefepime . But my labs came up that my nuetrophils and white count dropped to 3.72 . I also had gotten rdv while in cefepjne. My white cells came up to 4.0 this past month. Since brindupri is do new and my labs went liw in nuetrophils. And I literally have rare siddceffects now to mist medicines. I decided to not take brinsupri at this time. Does anyone have an opinion for m e. My doctors are very lack to busy to give me the time to sit down with a discussion. When first got told of brinsupri my one Dr did not even know of the side effects . She looked it up on the net . Im confused. It supposedly does something to your nuetrophils. Since mine are now very low I am concerned if it drops any lower what woukd happen. Any advise or thoughts please.