Bisoprolol for PVCs
Hello - I have recently been diagnosed with symptomatic PVCs
In July 2025. I was getting 1000s a day that I felt coming, skipped a beat then would feel a bang before squeezing my neck and head. I was given atenolol which I had to sleep 3 hrs in the afternoon. Then switched to bisoprolol 2.5 mg/day. I feel the intensity has gone down with the meds but I am still exhausted in the afternoon and need to rest for a bit. When I drive I still get bad episodes. I am also taking low dose nexium daily. Recently I have not been feeling like myself, get sad very easily, unhappy, mad at teenage kids. Like I have failed…and feeling very alone! Is this normal with the drug or is there a drug interaction? How long does it take to adjust? Thank you!
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I would have to say that's it's probably a little bit of everything....all of it. You have a significant new condition, and it's not fun (you are symptomatic, and that's almost never positive). You are worried, you are feeling helpless, you are exhausted, and irritants don't run past you without you swiping at them. I would say that it is normal. It's you....for now.
As for the Nexium: https://www.medicalnewstoday.com/articles/321164 Something to look into, wouldn't you say?
Thank you so much for your reply. Very interesting the nexium article. I have been taking for many years now but very low dose and did not have a problem until I started taking the bisoprolol.
Do you know if this is a good medication? I do feel like they are doing something to help but maybe creating more problems as well. Have you ever taken bisoprolol?
I feel like I get anxious also very easily despite the fact that my pulse is usually around 50! How long does it take to adapt- this new normal will be for months or years?
Thank you!
I take only atorvastatin and apixaban, and those are for risk to keep my chances of clotting and arterial blockage low. When I was fibrillating, I was on ever-increasing doses of metoprolol, but I never took bisoprolol and have not read much about it. The fact is that each of us is unique in how we respond to any kind of intervention, be it therapy or medication. Some do well on flecainide, some do poorly. Some can be successfully put onto Dofetilide while others cannot take it. Statins are okay for many, a great many, but it is well known that they cause all sorts of problems, chiefly sore muscles and joints, in some patients. So, all that to say you may indeed not be tolerating your combo well, and you should let your prescribing authority know, or at least your druggist/pharmacist...they can be very helpful.