I was curious to know if anyone had experience with autoimmune progesterone dermatitis? I have had severe allergic reactions including anaphylaxis and skin rashes. After positive progesterone skin testing with an allergist and failed attempts to tolerate even tiny doses of progesterone, I was diagnosed with APD (allergic reactions to my own progesterone). My immunologist and I have not had success with desensitization and we are hoping Xolair injections will help. I also have Lupus which has been aggravated by these frequent allergic episodes.