Hello @emily793, welcome to Connect. I can imagine how frustrating it must be trying to find a treatment that works. I don't have any experience with autoimmune progesterone dermatitis but found an article published Dec 2018 that may be related.

Progesterone hypersensitivity: Case report with favorable evolution
-- https://www.spandidos-publications.com/etm/17/2/1125

@zena, @smbryce1, @jimc522, @leilanis and @mscott1029 have discussed Xolair as a treatment in a post in other discussions and may be able to provide some information for you.

Have you and your doctor decided to try Xolair injections?

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