Aromatase Inhihibitors: Did you decide to go on them or not?

Posted by nanato6 @nanato6, Oct 12, 2018

Nanaloves: I’m about to start arimidex and just feel that the contraindications , bone issues etc. are overwhelming. I’m 70 years old, dodged a bullet I feel with zero stage DCIS but the follow up is pretty much no different then if it was more aggressive. I’ve just done 33 treatments of radiation and now they advise arimidex as a preventative. I’m not sure with the beginnings of arthritis and lower back. sensitivity already that I should take it. Anyone not take it and not have a recurrence within the 5 years.

I will be very interested in how you do on Aromosin. I have been on it for 2 weeks and the joint pain is awlful.

REPLY
@batm

I was only on Arimidex for about a month, the side effects were too much; also experienced an increased heart rate. My resting heart rate should be 60-70, its been floating between 83 and 103. Have no history of heart issues, no family history either. Echo was fine, EKG fine, bp fine, bloodwork fine. Seems coincidental that I’m feeling in now. Anyone else have any heart issues during or after Arimidex?? I’m not willing to try any other AI’s until this is resolved, cardiologist agrees.

Jump to this post

It is a known side effect

REPLY
@francine6829

What did your oncologist say about you going off of them?

Jump to this post

He wanted me to try another and I chose not to

REPLY
@cancersucks

He wanted me to try another and I chose not to

Jump to this post

Since my mammoprint came back very low, my oncologist put me on tamoxifen. He said it has no joint pain associated with it.

REPLY
@mimi99

I decided against it. I was diagnosed earlier this year, stage one,
negative nodes. I had lumpectomy and 3 proton beam treatments. I am
currently recovering from reverse shoulder replacement, have had two knee
replacements, lots of arthritis, and fibromyalgia. I am almost 70,
currently taking tamoxifen, and fingers crossed evdrything will go well.

Jump to this post

mimi99 or anyone else on Tamoxifen – I am about to start Tamoxifen because the Ais caused too much joint pain. My doctor said some of her patients had leg cramps and took Magnesium. What is your experience with Tamoxifen side effects

REPLY
@francine6829

mimi99 or anyone else on Tamoxifen – I am about to start Tamoxifen because the Ais caused too much joint pain. My doctor said some of her patients had leg cramps and took Magnesium. What is your experience with Tamoxifen side effects

Jump to this post

I was on Anastrozole for about 6 months and had miserable side effects, the worst was brain fog and I broke out in hives. The Hives are a more rare side effect, but my doctor thinks it was the Anastrozole. She switched me to Tomoxifin and the hives continued but not as severely. I ended up seeing an allergist, who put me on a brief course of steroids which cleared the hives completely. I went back on the Tomoxifin after the hives cleared up. However, I think I’d gladly put up with hives rather than the brain fog and issues with cognitive function. More info at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831410/

REPLY

lisman1408 – Have you had any other side effects from Tamoxifen other than the brain fog and possibly the hives?

REPLY
@francine6829

lisman1408 – Have you had any other side effects from Tamoxifen other than the brain fog and possibly the hives?

Jump to this post

It’s hard to say… I do have some aches and pains in my joints and bones, but I’m not sure what’s causing it. I’m almost 66, and was diagnosed with arthritis about 8 years ago-long before my cancer. I’m not sure if the arthritis is just progressing, or if it’s the cancer meds. This joint pain does seem to be better on the Tomoxifin than Anastrozole, but not enough to draw the conclusion that it’s caused by either medication.

It’s the brain fog that’s the worst for me. I’ve gotten to where I don’t even want to leave my house or interact with others. I repeat myself in conversations and can’t think clearly. I’m very embarrassed by it, so I just keep quiet and stay to myself as much as possible. My oncologist has given me a break for 3 months from the Tomoxifin. My cancer was very slow growing so she felt a break for a few months wouldn’t cause any harm. I do feel better off estrogen reducing drugs, and I believe I can think much more clearly without it.

REPLY
@francine6829

mimi99 or anyone else on Tamoxifen – I am about to start Tamoxifen because the Ais caused too much joint pain. My doctor said some of her patients had leg cramps and took Magnesium. What is your experience with Tamoxifen side effects

Jump to this post

@francine6829, you may be interested in these 2 discussions about Tamoxifen:

– What problems have you had with Tamoxifen? https://connect.mayoclinic.org/discussion/what-problems-have-you-had-with-tamoxifen/
– Can anyone speak to the pros/cons of arimidex vs. tomoxifen? https://connect.mayoclinic.org/discussion/can-anyone-speak-to-the-proscons-of-arimidex-vs-tomoxifen-ive-been-on/

REPLY
@colleenyoung

@francine6829, you may be interested in these 2 discussions about Tamoxifen:

– What problems have you had with Tamoxifen? https://connect.mayoclinic.org/discussion/what-problems-have-you-had-with-tamoxifen/
– Can anyone speak to the pros/cons of arimidex vs. tomoxifen? https://connect.mayoclinic.org/discussion/can-anyone-speak-to-the-proscons-of-arimidex-vs-tomoxifen-ive-been-on/

Jump to this post

Thank you!

REPLY
In reply to @francine6829 "Thank you!" + (show)
@francine6829

Thank you!

Jump to this post

Good morning everyone. Whenever someone posts their side effects of Arimidex (Anastrozole), I realize I'm not alone. I'm 74 and tend to think, "Well, this could be a result of my age", but it turns out that many people on Arimidex are experiencing the same side effects. I've been taking it for a year and a half now. I won't change to another drug because from the posts I've read here, they all seem to have similar or worse side effects. In a recent conversation with my Oncologist I told her I had read that Arimidex seems to have the best success at preventing a recurrence and she agreed. My question to all of you is has anyone who has also taken Arimidex for awhile had a recurrence of cancer?

Liked by cindylb

REPLY
@sparklegram

Good morning everyone. Whenever someone posts their side effects of Arimidex (Anastrozole), I realize I'm not alone. I'm 74 and tend to think, "Well, this could be a result of my age", but it turns out that many people on Arimidex are experiencing the same side effects. I've been taking it for a year and a half now. I won't change to another drug because from the posts I've read here, they all seem to have similar or worse side effects. In a recent conversation with my Oncologist I told her I had read that Arimidex seems to have the best success at preventing a recurrence and she agreed. My question to all of you is has anyone who has also taken Arimidex for awhile had a recurrence of cancer?

Jump to this post

The studies for estrogen inhibitors show all the drugs are effective in preventing reoccurrence. The patient should choose which has the least side effects

REPLY
@sparklegram

Good morning everyone. Whenever someone posts their side effects of Arimidex (Anastrozole), I realize I'm not alone. I'm 74 and tend to think, "Well, this could be a result of my age", but it turns out that many people on Arimidex are experiencing the same side effects. I've been taking it for a year and a half now. I won't change to another drug because from the posts I've read here, they all seem to have similar or worse side effects. In a recent conversation with my Oncologist I told her I had read that Arimidex seems to have the best success at preventing a recurrence and she agreed. My question to all of you is has anyone who has also taken Arimidex for awhile had a recurrence of cancer?

Jump to this post

sparklegram – Recurrance on AI's……that's a very good question. I'd like to hear about that as well….anyone?

Liked by sparklegram

REPLY
@francine6829

The studies for estrogen inhibitors show all the drugs are effective in preventing reoccurrence. The patient should choose which has the least side effects

Jump to this post

Francine6829, You are absolutely right! We each need to take a very active role in beating cancer for ourselves!

Liked by sparklegram

REPLY
@colleenyoung

Hi @mollyjbrown, I appreciate your posting about your experience living with Arimidex (anastrozole). For some people, it can certainly be a challenge to manage the side effects. You'll notice that I moved your message to this discussion where women are talking about tough choices: sticking with an aromatase inhibitor and coping with side effects or discontinuing the medication. It is a different risk calculus for everyone and each person experiences side effects differently. Thus, I'm grateful to add your story of how you manage the side effects and the choices you made.

@goldieshostak, you ask a very good question if your risk of recurrence is worth continuing with Arimidex. I encourage to read the post from Molly that was just added above this post. Ultimately the decision is yours. I recommend that you talk with your oncologist to discuss YOUR specific risk of recurrence.

I'm curious if anyone has used the CTS5 calculator (https://www.cts5-calculator.com/) with their oncologist to calculate their risk of recurrence? The tool is meant to be used with your doctor. You can read more about it here: https://www.breastcancer.org/research-news/online-tool-predicts-hr-pos-recurrence-risk

Anyone use it with their doc?

Jump to this post

I recently read that Arimidex can also compromise your immune system. I have asthma & have in the last 5 months had 2 cases of pneumonia. Do you think the AI – had contributed to this? I was not warned of this side effect. I've been on it since Nov. 2018.
Thanks.

REPLY
Please login or register to post a reply.