Anyone with chronic kidney disease after covid, with no other risks

Posted by kayabbott @kayabbott, 2 days ago

I got covid March 13, 2023 during a bike tour (vax 6 mo before, 70 yo). I was sick at home for 10 days followed by long covid (LC). The +8 months of LC mostly hit my cardiovascular (CV) system with BPs up to 196/79 and heart feeling like it was trying to escape my chest. Didn't go on BP meds because the BPs always came down to normal within 2 hours, just minimized exercise. No permanent CV damage. I have no risk factors for the stage 3a chronic kidney disease that was diagnosed last August. My avg systolic after LC ranges from 110 to 130. My kidney biopsy this week had ~50% damage to glomeri (50% function) but no cause, so they want me on BP meds in case that is it. I found research on covid causing kidney damage, but it was all severe and people in hospitals. My LC doctors don't know.

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dlydailyhope | @dlydailyhope | 1 day ago

@kayabbott
My understanding is the Covid spike protein damages endothelial cells that line your body. This can affect heart, lung, blood vessels and kidneys, etc.

1. https://www.nature.com/articles/s41581-018-0098-z
2. https://www.sciencedirect.com/science/article/pii/S0009898110004249
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696590/
4. https://www.kidneymedicinejournal.org/article/S2590-0595(24)00165-1/fulltext
5. https://www.kidneymedicinejournal.org/article/S2590-0595(25)00075-5/fulltext
6. https://www.nature.com/articles/s41401-022-00998-0
7. https://www.mayoclinicproceedings.org/article/S0025-6196(21)00607-8/fulltext
8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999560/

kayabbott | @kayabbott | 1 day ago

In reply to @dlydailyhope "@kayabbott My understanding is the Covid spike protein damages endothelial cells that line your body. This..." + (show)

Thanks so much for the links. Those help to answer some questions. Hypertension was an unlikely chronic kidney disease (CKD) cause due to my BP avg of 120/70 and being an athlete (less aerobic post LC but resistance is good). I have elevated HDL but not LDL (so much for friendlier cholesterol). The CKD happened at the end of ~8 mo of LC. Covid likely damaged the hair follicles on my arms and legs, but not elsewhere (had this happened as a teenager it would have saved decades of shaving). There was no permanent damage to my CV system, or the tubes in my kidneys, but my glioma are at ~50%. BP spikes during covid shouldn't have been enough for the damage, but it would be nice if there was more research on this. I suspect the covid research is being gutted as well.

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