Anyone using non-standard biologic dosing to manage side effects?

I was taken off Tyenne due to having a serious GI side effect. My doctor and I are investigating other available biologics to try with a reduced dose and/or lengthened interval between doses in an effort to limit the amount of drug I have in my system at any one time. The goal is to give me just enough to do the job while limiting/eliminating the potential side effects. This is done routinely with drugs your Endo Rx. Are there any others who are on this path a little ahead of me?

I would be interested in the drugs that have failed as well as the one you are on now and dosing approach you are using as well as any personal comments you feel free to share. We are considering several options, one oral the others injectables. I am not able to start the next drug until mid-May so I have time to do my research and am reaching out to see if others have had to deal with searching for a drug your body can tolerate.