Anyone in this clinical trial for low-dose Tamoxifen (LoTam)?

Posted by whitehairwisdom @whitehairwisdom, Jan 13 12:24pm

https://www.clinicaltrials.gov/study/NCT06671912

Is anyone part of this clinical trial which began in Feb 2025? Curious to know if you've had any side effects and what are they?

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Profile picture for jardinera25 @jardinera25

@jmab These studies (looks like they are available all over the US, according to initial poster's link!) are using 5 mg, or as some of us call it "baby Tam", but the study calls it "Lo-Tam." It's a 5 year study I think comparing it to AI's.

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@jardinera25 Seems my oncologist is pretending not to have heard of this and has an automatic no can do prepared.

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Profile picture for carolsue1234 @carolsue1234

@jmab I can't believe they used to give everyone 40 mg years ago, then they reduced it to 20mg and now we have to be scrappy to get it low enough to tolerate it. I don't want it to come back but I want to feel good.

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@carolsue1234 oh, I didn't know that they used to prescribe 40 mgs! I can't even imagine! Yes, I agree that we often have to scream to be heard. I'm doing ok on 10 mgs...slightly more brain fog, maybe. At 72, it's hard to know of the Tam is causing issues or if it's just my age! Anyway, I'll continue with the 10 mgs because I agree with you, I don't want it to come back!

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