Anyone had CAR-T treatment for Scleroderma or Lupus? Any other CAR-T?

Posted by Alta Net @altabiznet, 13 hours ago

Multiple CAR-T treatments are available now through clinical trials. Most studies are in Phase I or just entering Phase II. Meaning these treatments are early on in the development. The limitations to getting CAR-T treatments via research are many. Inclusion criteria are strict and clinical studies are recruiting only in certain areas.

Some very promising results have been published in Lupus. Scleroderma has very limited Phase I data. Although CAR-Ts showed a big promise in advanced patients, toxicities are serious: cytokine release syndrome and neurological toxicities.

If you had CAR-T in autoimmune disease, please share your experience: response to treatment and how bad were toxicities. How long did it take to recover?
Any insights are appreciated.

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

Please sign in or register to post a reply.