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DiscussionAnyone had CAR-T treatment for Scleroderma or Lupus? Any other CAR-T?
Autoimmune Diseases | Last Active: Jun 21 5:48pm | Replies (16)Comment receiving replies
Replies to "@becsbuddy Good morning..reason Becky is Systemic Lupus, Sjögren’s & type 2 Diabetes (under control AIC 6.1🎉..."
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@wendyhope
In case you are considering this treatment, for Lupus, there are many studies with CAR-T treatments that are recruiting now. As an example, there are three BMS Breakfree studies already ongoing. You can see the details in this link:
https://www.cartautoimmune.com/hcp
Breakfree-1 trial has multiple indications, including Lupus, Dermatomyositis, Systemic Sclerosis and RA. As a side note, Systemic Sclerosis is known to have ILD lung involvement similar to Sjorgren's. ILD is one of the primary endpoints for SSc. This version of CAR-T may be targeting more of the symptoms from multiple conditions, as opposed to single disease CAR-T. The decision, of course, is with your doctor. Breakfree-LE study is specifically for Lupus.