1. < Autoimmune Diseases

Success with low dose naltrexone for Autoimmune disorders

Posted by julie868 @julie868, Feb 13, 2020

Low Dose Naltrexone, otherwise known as LDN, seems to be helping a lot of people lately who have all different types of autoimmune disorders.
The information I read sounds very interesting and would like to know if anyone has tried it personally?

The theory that I read says that many autoimmune issues are caused by a deficiency in endorphins, endorphins regulate the immune system. LDN temporarily blocks the body's natural endorphin production for a few hours, this tricks the body into thinking it needs to increase endorphin production. When the blockade wears off, all the endorphins are released into the body, regulating the immune system and providing natural pain relief for the rest of the day. Apparently, LDN can increase your endorphins by up to 300%

LDNscience.org has a lot of information and research about it. You can also look at the writer, Annie Habler (@hablerannie) on Medium.com who wrote an article recently about the fascinating background and history of LDN.

Please let me know if you have tried it and what your experience was like. If you could let me know any details your condition,the dosage you used, any side effects, etc it would be helpful.

Thank you!

Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.

helennicola | @helennicola | Dec 18, 2021
In reply to @notgivingup17 "Thank you Helennicola!" + (show)
@notgivingup17

Thank you Helennicola!

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you’re welcome! 😁

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pacer3702 | @pacer3702 | Dec 19, 2021
In reply to @notgivingup17 "I just started LDN for chronic pain, I have prickling, shocking, sore muscles, pins and needle,..." + (show)
@notgivingup17

I just started LDN for chronic pain, I have prickling, shocking, sore muscles, pins and needle, and numbness that started in my left foot and has moved up my body. The pain seems to be causing muscle wasting. LDN has helped with my pain a lot but I haven't been on it long enough to know how well it will help me. I started at 1.5mg a month ago and I just went up to 2mg. I know it has helped my mood tremendously. I also take 50mg of Lyrica 2xdaily but I feel the LDN is help better than the Lyrica. I wish you well and thanks for bring this conversation up.

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If you have motor neuropathy, that can cause muscle wasting.

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goodfriends | @goodfriends | Dec 25, 2021

It put me in remission on my autoimmune rx when I was allergic to all the meds tried...we were to the point of Prednisone only and eight years is too long to be on it ....I appealed to my support group online and a nurse who had the same AI gave me Wahl's protocol and LDN ..severe dietary regimes long term I knew I would fail at so it was LDN...having been through anaphylaxis again and again had me nervous but talking to a demonstrator who wife was put into remission on LDN gave me the courage to try it....I had been warned I might experience the flu like symptoms ever I pushed through the hem for three weeks ...woke up one morning to no pain for a the first time in eight years....it is now going on nine years in remission....and it didn't interfere with my Covid vax....give it a try..just wish I had it to start with ...it has the least number of side effects and I got a lot of damage from not getting into remission sooner

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goodfriends | @goodfriends | Dec 25, 2021
In reply to @johnbishop "Hello @goodfriends, Welcome back to Connect. I see that you last posted in 2011. Thank you..." + (show)
@johnbishop

Hello @goodfriends, Welcome back to Connect. I see that you last posted in 2011. Thank you so much for coming back to Connect and sharing your experience with low dose naltrexone (LDN). To be in remission for almost 8 years is no minor accomplishment. Your experience with LDN is an encouraging one that can offer others with Relapsing Polychondritis some hope and possible answers in their search for something to help.

@nibor63 @mcwilliamssr @rpwarriorlady @monikamouse @ethellee97 and @polytina have posted in the Relapsing Polychondritis discussion here: https://connect.mayoclinic.org/discussion/relapsing-polychondritis/ and I'm sure will be interested in your story.

I also tried the Wahls Protocol diet for a few months and found it somewhat difficult and I only stayed on it a few months. It did really start my journey on eating healthier and focusing on nutrition vs junk and processed foods. You mentioned you made the decision between the Wahls Protocol diet and LDN and went with the LDN as an option to help your Relapsing Polychondritis. Did you make any other diet or lifestyle changes that helped you?

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I pretty much follow anti inflammatory diet....I can now handle bread milk and a lot of others that initially were so f the table ...in addition I lost 120 lbs of pred weight ...I gained 80 lbs the first month I was pred

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Saundrella | @saundrella | Dec 25, 2021
In reply to @helennicola "FYI : there are Facebook forums regarding LDN; many with Sjögren’s and other autoimmune issues successfully..." + (show)
@helennicola

FYI : there are Facebook forums regarding LDN; many with Sjögren’s and other autoimmune issues successfully take it. If you’d like to hear experiences from other LDN users you can ask to join these groups..

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I tried the link you shared, another link showed up saying, "Jump to link" and, when I clicked on it, the site showed up but, just as quickly as it showed up, it disappeared. No matter how many times I tried, the same happened. Any suggestions?

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1 reply
Saundrella | @saundrella | Dec 25, 2021

I would like to know about LDN and PBC, primary biliary cholangitis, another autoimmune disease.

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1 reply
helennicola | @helennicola | Dec 25, 2021
In reply to @saundrella "I tried the link you shared, another link showed up saying, "Jump to link" and, when..." + (show)
@saundrella

I tried the link you shared, another link showed up saying, "Jump to link" and, when I clicked on it, the site showed up but, just as quickly as it showed up, it disappeared. No matter how many times I tried, the same happened. Any suggestions?

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I didn’t provide a particular link, just suggested you type in LDN groups maybe, I was made aware via the Sjögren’s FB group.

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Moderator
Colleen Young, Connect Director | @colleenyoung | Dec 25, 2021
In reply to @saundrella "I would like to know about LDN and PBC, primary biliary cholangitis, another autoimmune disease." + (show)
@saundrella

I would like to know about LDN and PBC, primary biliary cholangitis, another autoimmune disease.

Jump to this post

Hi Saundrella, you may wish to connect with other members talking about primary biliary cholangitis (PBC), previously called primary biliary cirrhosis, in these active, related discussions:
- Primary Biliary Cholangitis and Autoimmune Hepatitis https://connect.mayoclinic.org/discussion/primay-biliary-cholagitis-and-autoimmune-hepattitis/
- Is it safe to take Milk Thistle with Primary Biliary Cholangitis? https://connect.mayoclinic.org/discussion/primary-biliary-cholangitis/
- Primary Biliary Cholangitis: I would like to connect with others https://connect.mayoclinic.org/discussion/primary-biliary-cholangitis-stage-2/

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aus12 | @aus12 | Nov 3, 2022

Interested in results of Low dose naltrexone for pain autoimmune patients.

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1 reply
aus12 | @aus12 | Nov 3, 2022

Interested in the results of using low dose naltrexone in autoimmune patients

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