Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

Posted by dedehans @dedehans, Aug 20, 2022

My close friend has had Pluvecto treatment suggested to him by oncologists. It is relatively new, having been approved by the FDA in March 2022. Have any of you been given this drug? I have read it is radioactive material and patient needs to stay away 6 ft from others for at least 3 days so as not to contaminate them. He has not yet decided whether to take the treatment or not as he is feeling awful enough as is.

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

Colleen Young, Connect Director | @colleenyoung | Dec 1, 2023

In reply to @digger "I’m in the process of getting pluvicto I had trouble with the last chemo treatment so..." + (show)

Hey @digger, I moved your post about Pluvicto to this existing discussion in the Prostate Cancer support group
- Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?
https://connect.mayoclinic.org/discussion/any-one-on-pluvecto-a-relatively-new-drug/
I did this so you can easily connect with other members on this treatment like @andrejacques @gaherrma @dlylecpa @robert570 @donalan @leebeth @bamaples @dwpoole @stonewalker and who may be able to answer your questions about blood work and getting treatment.

digger | @digger | Nov 28, 2023

I’m in the process of getting pluvicto I had trouble with the last chemo treatment so pluvicto is next,how much trouble have you had with blood work my platelets,hemoglobin,white and red cells are low im not sure they’ll give it to me if it’s that low before getting pluvicto I’m worried thanks

eercat81 | @eercat81 | Nov 3, 2023

I’ve had 4 Pluvicto treatments so far (1 every 6 weeks). I have two more as that is protocol and all insurance will pay for. My psa is now under control. The treatment side effects are minimal. I do have to keep my distance after treatment but it’s worth it. So much better than chemo!

Colleen Young, Connect Director | @colleenyoung | Oct 20, 2023

In reply to @eercat81 "I had my 4th treatment and psa down to .27 Few side effects My concern is..." + (show)

@eercat81 @gaherrma, you may be interested in this related discussion:
- What is the recommended treatment after 6 Pluvicto doses?
https://connect.mayoclinic.org/discussion/what-is-the-recommended-treatment-after-6-pluvicto-doses/

kaschu83 | @kaschu83 | Oct 20, 2023

In reply to @hpete710 "My dad has had 1 treatment so far. He was in bad shape going into it-..." + (show)

@hpete710 how is your dad doing now? I found this group looking for Pluvicto side effects as my dad just received his first treatment and has been fatigued and nauseous since. He seemed to be recovering three days after only to have a huge setback, have lots of diarrhea, supposedly a c. diff infection and now seem to be fighting for his life. Huge hugs to you and your family. It is so hard to watch a loved one suffer. 😥

gaherrma | @gaherrma | Oct 18, 2023

In reply to @eercat81 "I had my 4th treatment and psa down to .27 Few side effects My concern is..." + (show)

I'd like to hear what folks are being told from their doctors about what happens after the first six treatments of Pluvicto?

Can patients get another 6 ?

Gina, daughter of John

eercat81 | @eercat81 | Oct 7, 2023

I had my 4th treatment and psa down to .27
Few side effects
My concern is what is next? Six treatments is the limit.

rrosberg1 | @rrosberg1 | Sep 26, 2023

In reply to @cjbbjc2010 "Can anyone give feedback on how Pluvicto treatment response is being determined? is it MRI, CT,..." + (show)

Had PSMA rejected by Aetna twice. After several appeals they approved it. The back story was $$$. The hospital where it was scheduled was going to charge approx. $18K. After I shopped around a private oncology center quoted me less than $6K. The approval was given after the hospital agreed to approx. this amount. My inquires indicate that Aetna was slow on approving other things. I moved to United.

cjbbjc2010 | @cjbbjc2010 | Sep 25, 2023

Can anyone give feedback on how Pluvicto treatment response is being determined? is it MRI, CT, a PSMA PET scan with F-18 or G-68 agent? If with PSMA PET, has insurance been covering it? Cost is a concern. thanks