Any Experience with Ciprofloxacin?

Posted by narelled23 @narelled23, Sep 11 11:29pm

History of Bronchiestases and COPD.

I have been sick for 3 of the last 4 months...and almost continually for the last 2 months. Started as cold like for couple of weeks...get better for a couple of days and then come down again. It developed into a severe sinusitis type infection. Early nasal swab and more recent sputum showed nothing sinister although no AFB testing was done.

A course of Azrithromycin was followed by Amoxicillin and then 2 rounds of Augmentin (because of a skin infection I also had – plunging hands into potting mix while I had some broken skin). While initially these antibiotics seemed to help they didn't kill whatever is ailing me.

At one point on a weekend I tried the young 'on call Dr' at my local clinic and he said I needed to switch antibiotics and put me on Cefuroxine, gave me a referral for chest Xray to rule out Pneumonia, and a referral for ent scope of my throat area...because one of the symptoms I have been experiencing is the feeling of my throat closing and stopping my breathing. (Have decided to leave the scoping for the moment).

I woke the next morning with laryngitis type symptoms and shortness of breath on walking.

The Xray and a subsequent blood test for inflammation markers came back negative (however I had also been on a 5 day Prednisolone course).

The pulmonary rehabilitation program I have previously been doing had suggested that nebulising hypertonic may be causing some of my excess mucus problems (up to 3 cups daily) and so I did cut down to 2 or 3 times a week for a while there, but back to once a day now. Doctors have found no reports of chest noises.

Yesterday I managed to get in to see a more senior GP I used to see and he strongly recommended I go straight on to a long course of Ciprofloxacin immediately to DRENCH all potential cavities in lungs/other non blood fed areas etc, and told me to stay on the antibiotic for a week after I am symptom free. He did warn about tendinopathy…but since I have taken the first tablet and done some research, I have discovered that it can be a very dangerous antibiotic…and I have had a bit of feedback from the LM people on Facebook, with stories of people’s problems after being on Ciprofloxacin. Understandbly they are very negative about the fact that no sputum testing for AFB/Pseudomonas was done… however the original nasal swab and subsequent ordinary sputum done between antibiotics did not show anything, unfortunately no AFB testing done.
Despite the fact that I have been on so many antibiotics and am currently on Ciprofloxacin now, AI suggested I could still submit a sputum for analysis, which I have done this morning.

It is difficult to find a GP (PCP) here in Australia, for acute events, who is really knowledgeable about Bronchiectasis, NTM, Pseudomonas etc and it can take months to get in to see a respiratory specialist.

The research article I found here is Australia about side effects of Ciprofloxacin is below.
https://australianprescriber.tg.org.au/articles/fluoroquinolone-antibiotics-and-adverse-events.html
I would love to hear any wisdom or feedback you could give me. Many thanks.
Narelle

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Profile picture for Sue, Volunteer Mentor @sueinmn

@narelled23 Not too late! Please, please get a pulmonologist appointment so you can have a culture done and get on the correct antibiotics for the correct amount of time. Repeated short courses without knowing what bacteria you have has not been working for you these past months.

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@sueinmn
Sue, are you suggesting I should stop this course of antibiotics to get a pulmo appt and sputum? Is there not a danger in stopping a course of antibiotics just after starting them?

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Profile picture for narelled23 @narelled23

@sherrig
May I ask if your lung function returned after finishing the drug?

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@narelled23 Yes it went back to normal in 2 days. I had a PFT 6 months after finishing the colistin and there was not change from the PFT 2 years ago.

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My experience with Cipro caused a tendon ache so the dr put me on Tobramycin.
The infection cleared but now tinnitis is real but tolerable

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Profile picture for sherrig @sherrig

@narelled23 Yes it went back to normal in 2 days. I had a PFT 6 months after finishing the colistin and there was not change from the PFT 2 years ago.

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@sherrig
That is great news. Well done.

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Profile picture for narelled23 @narelled23

@sueinmn
Sue, are you suggesting I should stop this course of antibiotics to get a pulmo appt and sputum? Is there not a danger in stopping a course of antibiotics just after starting them?

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@narelled23 No! What I meant was to not seek any further treatment except through the pulmonologist, share everything you have already tried, and get a definitive diagnosis before trying more, different antibiotics without knowing exactly what bacteria or fungus you are fighting.
If you have MAC, Pseudomonas or a fungus or mold infection, each has a specific treatment protocol.

An emergency department and many GPS simply keep trying long list of antibiotics, frommildest to strongest, until one works. In the meantime the underlying infection continues to grow. For example, Cipro might work on pseudomonas, but not on MAC or a fungal infection.

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Profile picture for Sue, Volunteer Mentor @sueinmn

@narelled23 No! What I meant was to not seek any further treatment except through the pulmonologist, share everything you have already tried, and get a definitive diagnosis before trying more, different antibiotics without knowing exactly what bacteria or fungus you are fighting.
If you have MAC, Pseudomonas or a fungus or mold infection, each has a specific treatment protocol.

An emergency department and many GPS simply keep trying long list of antibiotics, frommildest to strongest, until one works. In the meantime the underlying infection continues to grow. For example, Cipro might work on pseudomonas, but not on MAC or a fungal infection.

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@sueinmn

Thank you. I intend to ring the Royal Perth Hospital pulmonary rooms tomorrow to get advice.
Much appreciated.

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Profile picture for amap2025 @amap2025

My experience with Cipro caused a tendon ache so the dr put me on Tobramycin.
The infection cleared but now tinnitis is real but tolerable

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@amap2025
Sorry to hear that, but glad the infection cleared and you are coping. 🙏

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Profile picture for irenea8 @irenea8

Is there any way you can see a Pulmonologist without waiting too long? I would be very wary of the GP's advice in this instance. You have asked about sputum and usually with Pseudomonas the sputum is rather brownish yellow and alot of it.

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@irenea8 I have pseudomonas and my mucus is thick and clear. I am new to this and I get no info from my doctors, so I am flying by the seat of my pants

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If you have Bronchiectasis or CF you need to see a Pulmo who specializes in those areas or infectious disease Dr possibly. Some people do not get as much trouble from their Pseudomonas and it is milder while others have a heavy load. Your clear sputum is a good sign. Can you find a pulmo who specializes in your area?

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Profile picture for annasill @annasill

@irenea8 I have pseudomonas and my mucus is thick and clear. I am new to this and I get no info from my doctors, so I am flying by the seat of my pants

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@annasill
Interesting to hear...thank you.

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