Anxiety adrenaline waves every AM waking me from sleep.

Posted by esikora @esikora, Nov 13, 2021

Hello,
As stated above,every AM at around 5, I start having uncomfortable adrenaline-like waves throughout my body. If I try to sleep, the waves cause weird dreams and then I wake up. This has been going on for about eight months. There has been considerable stress in my life during this time, but now things are improving, but the waves are just as bad.
Has anyone ever experienced this?
Thanks.

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@katiedid

I had a scan (mri) of the abdomen back on 4/26, and I have to have another one of the pelvis, which takes 30 minutes. Since I didn’t hear anything as far as findings are concerned with regard to the first scan, I have to presume that this tumor is not on either of my adrenals, or anywhere else in my abdomen, or that, possibly , the gadolinium contrast just failed to demonstrate, and that would mean I might have to have a more sensitive test, like an MIBG scan. My BP is great, but these “Pheo” spells occur randomly, and they cause these “feelings of doom”, where I can wake up suddenly and experience a sense of doom. These bother me worse than the BP issues, so I have to get to the bottom of this, because it is seriously affecting my quality of life. Thank you for reaching out to me, I appreciate it.

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I had a CT scan with contrast last week and I’m still waiting for results.
I know I have an adenoma on my left adrenal from a scan that was done nine years ago. All the doctors I spoke with said it was nothing to worry about. Even though, I was having adrenaline rush often.
They convinced me it was just my anxious personality. Funny I haven’t always had an anxious personality.....
Anxiety seems to be the “go to” diagnosis for many things.

I also feel I have to finally get to the bottom of this, but it has been very difficult.
Please let me know what happens with you, and I will let you know what I learn too.
Good luck to both of us!

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@5148branelly

Are you sure you were on 2-4 mg of clonazepam (Klonopin)? That is a huge dose! The usual starting dose for clonazepam is 0.25 mg. twice a day.
Clonazepam is in a drug category called “benzodiazepines,” which includes Valium, Ativan, Xanax and many others. These drugs can be very helpful in the treatment of anxiety. Anxious people, IMHO, tend to be “control freaks” which is not necessarily a bad thing. Yes, benzodiazepines can be mildly addictive, but from what I’ve observed, anxious people find the dose that works for them (usually a low dose) and stay on that dose that helps them. Oddly, from a chemical standpoint, anxious people don’t seem to reach tolerance on benzos. Tolerance is where a person takes a given dose, but in a short time, the drug is no longer effective and the dosage must be increased in order to get the same effect. Tolerance develops quickly with narcotics (=opiates).
An anxious person might need to be on a “their” dose of a benzo for years. If it is a reasonable and effective dose, I don’t see that as a problem.
With the help of a psychiatrist, find the dose that completely relieves the anxiety. Stay on that dose for 3-4 months (or forever if you like). Then start to taper slowly w/ the help of your psychiatrist. With say, Ativan, an anti-anxiety dose might be 1 mg three times a day. Once you’ve taken that for 3-4 months, begin a slow taper (about 0.25 mg a month) until you reach the dose at which the anxiety recurs. Increase the dose by 0.25 mg. That is “your” dose and you can stay on it indefinitely. A great deal of paranoia has developed about benzodiazepines. It is true that IN COMBINATION with other drugs, respiratory depression can occur. Even death might occur but chances are that it is caused by an opiate that was prescribed with a benzo.
On their own, benzos are among the safest of drugs. It is extremely hard to overdose on them and most cause virtually no side effects.
If you have had cancer (or some other major traumatic event) and believe that you are anxious about a recurrence, find a dr. that will work with you on this. During crises, you may find yourself needing to go back up a milligram or two, but when the crisis abates, taper (w/ a dr.) yourself back down to the minimal dose that works for you.
Gabapentin and Lyrica are drugs that can also be used for some types of anxiety.
But some of the substitutions for benzos that I’ve seen cause more trouble than they are worth—far more trouble than sticking with a low dose benzo might.
Some have been prescribing atypical anti-psychotics for anxiety and sleep. These drugs can help, but they can also cause EPS (extrapyramidal symptoms) which are disconcerting muscle movements that can be treated with Cogentin quickly and easily. Less pleasant side effects are tardive dyskinesia, which are involuntary muscle movements—like tapping a finger, twisting a hand, facial grimaces and tongue protrusion. Akathisia, which is involuntary foot tapping, may also occur. These can be helped somewhat with propranolol. Tardive dyskinesia is permanent though. I think few patients are told about the risks of using these drugs for any length of time, even as they are being excessively cautioned about benzos.
If you are anxious and/or depressed, individual psychotherapy can help. Group therapy and support can also be very helpful especially if you are taking the appropriate medication.

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I don't think 2 to 4 mg of clonazepam is high dose. I have taken 2 mg before bedtime for several years and have dropped off of it several times with no withdrawal side effects. I do agree, the patient needs to evaluate themselves to see what the lowest dose is that gives the desired effect, according to their metabolism and how the patient's body breaks down that particular benzo. When I on rare occasion took an additional 2 mg clonazepam during the day and tried driving, my reaction times were quite a bit slower as a result. I have had general anxiety disorder (GAD) for practically my entire life (76 years old now), it isn't a horrible thing, but I hate it nonetheless.

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