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Anyone heard of ANXV (Annexin A5) for Retinal Vein Occlusion (RVO)?
Greetings. Has anyone ever heard of ANNEXIN A5 for RETINAL VEIN OCCLUSION? I've heard that it's currently in phase 2 clinical trials and that it could potentially dissolve the OCCLUSION making further injections unnecessary. But please double check me on this. It's just what I think I heard. No promises on my end. Thank you and have a great day.
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Has anyone at Mayo heard of ANNEXIN A5 for RETINAL VEIN OCCLUSION? I've heard that it is in phase 2 clinical trials. Please double check me.
@dantheman31, this is what I could find.
"ANXV (a human recombinant Annexin A5) is well-tolerated and safe in Phase 1 First In Human clinical trial and is currently in Phase 2 in Retinal Vein Occlusion." https://iovs.arvojournals.org/article.aspx
I found the phase 2 study to which you're referring being conducted in the UK:
- Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion (NEXUS) https://clinicaltrials.gov/study/NCT07259928
To find out about clinical trials available at Mayo Clinic you can contact Clinical Trials
https://www.mayo.edu/research/clinical-trials
Phone: 800-664-4542 (toll-free)
https://www.mayo.edu/research/clinical-trials