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dantheman31 avatar

Anyone heard of ANXV (Annexin A5) for Retinal Vein Occlusion (RVO)?

Eye Conditions | Last Active: Apr 18 12:18pm | Replies (2)
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Has anyone at Mayo heard of ANNEXIN A5 for RETINAL VEIN OCCLUSION? I've heard that it is in phase 2 clinical trials. Please double check me.

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Replies to "Has anyone at Mayo heard of ANNEXIN A5 for RETINAL VEIN OCCLUSION? I've heard that it..."
Colleen Young, Connect Director | @colleenyoung | Apr 26 1:17pm

@dantheman31, this is what I could find.

"ANXV (a human recombinant Annexin A5) is well-tolerated and safe in Phase 1 First In Human clinical trial and is currently in Phase 2 in Retinal Vein Occlusion." https://iovs.arvojournals.org/article.aspx

I found the phase 2 study to which you're referring being conducted in the UK:
- Safety and Proof of Concept Study of ANXV (Annexin A5) in Patients With Diabetic Retinopathy or Retinal Vein Occlusion (NEXUS) https://clinicaltrials.gov/study/NCT07259928

To find out about clinical trials available at Mayo Clinic you can contact Clinical Trials
https://www.mayo.edu/research/clinical-trials
Phone: 800-664-4542 (toll-free)
https://www.mayo.edu/research/clinical-trials

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