Anyone experience mood swings and nervousness with Anastrozole?

@pktaylor59 I hope you can keep going , I find it helps to know that ‘it’s not just me’ and know of how other people cope , I suppose you could call it ‘strength in numbers’.

It seems to be an unfortunate of ALL the ai drugs. Probably due to the absence of estrogen. I did have chemo so at first attributed it to that (good old chemo brain) but do feel it’s a lot due to the ai therapy. Been on Anastrazole and exemestane and had problems with both. Would forget what I was going to do - 10 second after I decided to do it, couldn’t find my words. Gets scary. Get to start Letrozole in a couple weeks so will let you know if that one does it as well.

I too have the exact experience except no chemo only radiation. The hormone blocker has me befuddled. My Dr tried putting me on memetine ( a med used for dementia and Alzheimer's). It made me hurt all over and experience restless , even more confused. I am goin to stop it at my next appt
I am convinced the hormone blocker anastrozole is the culprit. I need it for atleast 5 years . But no more additional meds. I was better off before with just anastrozole

@green1 this is part of my problem. What I refer to as “circular medicine”. I have this problem which is a side effect to the medication I need to be on. So they want to put me on another medication to treat these side effects which has its own side effects. Then we try to treat those side effects with yet another medication. Like - am I depressed? Probably BUT is it really depression or is it because I no longer have any estrogen which causes depression, mood swings, insomnia, fatigue, weight gain etc. So why do I want another medication that causes suicidal thoughts and of course - mood swings, insomnia, fatigue, weight gain. I just try to tell myself I only have (hopefully) another 2 1/2 years on this and just need to deal the best I can. My biggest concerns now are when that time comes a) will they recommend I go longer b) will tumor come back now that there’s no meds so SHOULD I continue and c) will any of these side effects be permanent after that amount of time. (Again, and why are we depressed?)

@mistymar absolutely
My doctor was so happy to tell me patients can now safely stay on for 10 years! No thanks ill be feeling like im 10 by then. When my promised 5 ears are up Im out!

Yes the solution suggested was to take yet snother med to counter act anastrozole brain fog. I eas told it is an Alzeimer drug tried it again no thanks

Last text today i forgot to go home from work…stayed 1 hour over……

@green1 I do agree. Mine said 5 years and research shows no difference in reoccurrence whether 5 or 10 on the ai. And that was on first visit before staging was even done. I’m getting ready to start the 3rd one and if problems, then we try Tamoxifen. Anyway, same as you - I will really argue the point if they try to go longer.

@green1 Me too - can’t wait will be counting the months out!

@mistymar I agree with your thoughts on this entirely. Am at the same stage in treatment as you , it is awful to wish your time away but 2029 can’t get here fast enough!! Keep going best of luck.