Anastrazole and anxiety

Posted by momandrph048 @momandrph048, Jun 14, 2023

Has anyone else taking an aromatase inhibitor been dealing with crying very easily, and anxiety that comes out of nowhere?? It doesn’t seem to be related to anything, it just appears out of the blue.. My oncologist has me on Effexor, but it doesn’t seem to be doing that much and I really don’t want to increase my dose.. Can anyone share a similar story? Counseling isn’t really for me, I just need to deal with it on my own, and I really feel that the medication is the reason for it.. Mostly because my dr had me stop it for a couple weeks due to joint pain and everything got better.. Thanks for your input!

Interested in more discussions like this? Go to the Breast Cancer Support Group.

Profile picture for danielleboily @danielleboily

Thank you,
I will be seeing a n oncologist In december,I'm from Quebec and healt care is often slow.
I'm 81trs old without a personal doctor.

Jump to this post

I am from Ottawa and 87. I have been on Anastrozole for four years and have had a sleep problem since plus
losing hairs all over the house every day. I can’t wait to get off of it but my dr. thinks it’s a good idea to take it another two years. I am sorry you don’t have your own dr.. I hope you are on a wait list and that you can at least get care when you need it.

REPLY

This is completely my experience also. I too do not want to take any further medication ( enough side effects already from Anastrozole) and don’t need to add to these. I find social situations problematic at times as the onrush of tearful emotion is often so random and impossible to batten down. I do think this is a side effect of the drug that warrants more investigation as it’s impact on quality of life is quire daunting.

REPLY
Profile picture for mari @mari

Anestrozole ruined 4 fingers. Needed surgery on pointer.
More surgery threatened. It's not that effective of a drug.
I went off of it.
Saw hand dr. - Had Hand PT.
I was developed by Satan. Horrible drug. The worst side effects.

Jump to this post

I’m getting ready to start Anastrazole and I’m very nervous about it. What did it do to your hands?

REPLY

Here's what I think..................since all of these AI's are "hormone receptors" that is exactly what they do. Mess with your hormones. They stop estrogen and cause a bunch of hormonal changes in all of us that take them. I don't know how we can get around not having emotional changes when we take them to stop fueling the cancer cells. They make us cry and have emotional outbursts. We get very moody and are just plain miserable. All we an do is pray that they work in stopping the cancer. This is just my opinion.

REPLY
Profile picture for reflector75 @reflector75

I am sorry you are having these problems but also interested in your post. I have been on Anastrozole for just over a year and have been experiencing worsening panic attacks and uncontrollable feelings of impending doom and uncontrollable crying for the last six months or so. My cancer diagnosis was very similar to yours and from the viewpoint of clear mammogram etc all looks well. Whilst I have had a history of panic attacks previously the current attacks are off the scale. I am becoming increasingly concerned that Anastrozole is key to these symptoms and will hope to discuss this with my oncologist at an upcoming review. I feel it maybe that patients who have previously diagnosed panic/ anxiety conditions may be more likely to experience these more extreme reactions. Possibly this could be a fruitful area for research into the side effects of AIs.

Jump to this post

I have chosen to stop all of them including Anastrozole
I have had no quality of life.
I am 76 yrs old and I am going to take my chances of untreatable cancer recurring

REPLY
Profile picture for lansing @lansing

I have chosen to stop all of them including Anastrozole
I have had no quality of life.
I am 76 yrs old and I am going to take my chances of untreatable cancer recurring

Jump to this post

I feel I may eventually take this path too as I am the same age as yourself. One of my Oncologists has suggested that if I could get to two and a half years in treatment this could be an option to consider.

REPLY

I am struggling with the anxiety aspect of side effects from this drug. It is good to know that how I feel is very much related to this drug. The anxiety plus bone density issues are the two side effects that seem to be happening to me.

REPLY

On Anastrozole just over a year and half. Age 73, active/healthy, other than my "decades old breast cancer" returning in my lymph nodes. The Anastrozole really did its job - reduced the cancer size so they could do surgery - then had 16 rounds of targeted radiation. My oncologists pushed for Chemo then CDK but I declined due side effects and my age - they did recommend ZOMETA infusions every 6 weeks - not for osteoporosis but to prevent this cancer from metastasizing in the bones - this month will be getting a second infusion. This biggest problem is that AI's are hard on your heart, bones and also can be associated with dementia. Personally will stay on Anastrozole no more than 2 years unless they find my cancer is coming back which my oncologists seem to think is likely. Unfortunately oncologist offer only solutions that poison or made us weaker and more susceptible to other diseases - especially if we are in the "elderly" category. I am keeping close tabs on ANKTIVA/BioShield and hopeful the FDA will approve for ALL CANCERS - this treatment alone or with other cancer drugs like Chemo are strengthening cancer patient's immune system/NK cells - successful for bladder, brain and lungs cancers. This make sense - all cancer patients need to ensure they are checking their ALC levels - your lymphocyte count should be above 1000. Only 4.6% of patients with lymphocyte counts under 1000 were alive 4 years after surgery compared to 23% with lymphocyte counts above 1000. Old age, chemo, radiation all reduce lymphocytes. I am hoping to hold off my cancer and the destruction of my health with traditional cancer drugs - optimistic ANKTIVA will finally become available for all cancer patients and we will be allowed to strengthen our own immune system NK cells.

REPLY
Profile picture for aubreybill @aubreybill

On Anastrozole just over a year and half. Age 73, active/healthy, other than my "decades old breast cancer" returning in my lymph nodes. The Anastrozole really did its job - reduced the cancer size so they could do surgery - then had 16 rounds of targeted radiation. My oncologists pushed for Chemo then CDK but I declined due side effects and my age - they did recommend ZOMETA infusions every 6 weeks - not for osteoporosis but to prevent this cancer from metastasizing in the bones - this month will be getting a second infusion. This biggest problem is that AI's are hard on your heart, bones and also can be associated with dementia. Personally will stay on Anastrozole no more than 2 years unless they find my cancer is coming back which my oncologists seem to think is likely. Unfortunately oncologist offer only solutions that poison or made us weaker and more susceptible to other diseases - especially if we are in the "elderly" category. I am keeping close tabs on ANKTIVA/BioShield and hopeful the FDA will approve for ALL CANCERS - this treatment alone or with other cancer drugs like Chemo are strengthening cancer patient's immune system/NK cells - successful for bladder, brain and lungs cancers. This make sense - all cancer patients need to ensure they are checking their ALC levels - your lymphocyte count should be above 1000. Only 4.6% of patients with lymphocyte counts under 1000 were alive 4 years after surgery compared to 23% with lymphocyte counts above 1000. Old age, chemo, radiation all reduce lymphocytes. I am hoping to hold off my cancer and the destruction of my health with traditional cancer drugs - optimistic ANKTIVA will finally become available for all cancer patients and we will be allowed to strengthen our own immune system NK cells.

Jump to this post

@aubreybill
Thank you so very much for your comments.
I have been on Anastrozole for six years.
My eye doctor says that it may have contributed to a problem that will require surgery.
However, the same problem mentioned is one my mother had, and she never had
cancer nor Anastrozole. So, here we are.

Thank you again. God Bless and wishes for save keeping. And, oh by the way,
I am 82. I am working with a school system as their needs materialize.

Joyce Hendrixson

REPLY
Profile picture for jhendrixson @jhendrixson

@aubreybill
Thank you so very much for your comments.
I have been on Anastrozole for six years.
My eye doctor says that it may have contributed to a problem that will require surgery.
However, the same problem mentioned is one my mother had, and she never had
cancer nor Anastrozole. So, here we are.

Thank you again. God Bless and wishes for save keeping. And, oh by the way,
I am 82. I am working with a school system as their needs materialize.

Joyce Hendrixson

Jump to this post

@jhendrixson you sound amazing. Hang in there - honestly believe we are on the eve of a cancer cure - have never been closer.

REPLY
Please sign in or register to post a reply.