Am I the only one that’s in denial?

@llander1966
My story. Too many other things wrong with me and cannot imagine something else and the anxiety about being crippled doesn’t help.

@boneoptimist If you're taking Tymlos, you're not getting brittle bones. That was a problem when Fosamax was the only medication on the market: it didn't really build good bone density. Tymlos does. Afterwards, Fosamax helps preserve those gains. And, you don't have to take it forever. It's recommended to take drug holidays every so often, where you take a couple of years off (Fosamax stays in the bones for a long time, so a holiday is OK.)

@njx58 , i was referring to the drug after Tymlos. I plan on not taking Fosamax. I will choose something else, or nothing al all, and up my exercise and monitor via bloodwork and Dexa for the first 6 months. We'll see!

@indenial , I also saw this study about various drugs and the loss rate after stopping them. Unfortunately, Tymlos (abaloparatide) is not included. I worry about bone loss and brittle bones from bisphosphonates. My mom did Fosamax, and her jaw was like Swiss cheese. I'm not looking forward to deciding what's after Tymlos if I can't keep my BMD up after ending it.
Here's the study:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8519894/
Hope it's helpful!

@boneoptimist Would one year of Evenity be a temporary solution for you?

@boneoptimist I agree. For me, I am totally paranoid about even starting the drugs because of the side effects. Then there is the rate of bone loss when I stop taking the drug. And the possibility, although it is very low, of osteonecrosis. I do read about women taking different bone drugs, and it does not do anything to improve the density, or only very little. So, it is almost like a gamble.

@wilweten , honestly if I can't maintain whatever BMD I get to (in this next year on Tymlos) by keeping my routine up after stopping Tymlos, Evenity might be what I'm leaning toward. So much can change in a year, so I will start heavier research on my end in about 6 months, and hope that new studies/research come out meanwhile that can guide me. Fingers crossed!

I wanted to be in denial, but PC, endocrinologist, and orthopedic all said absolutely not when I asked about delaying meds. (-3.9 spine) I am hoping I can choose no meds after two years on Tymlos, or a new vaccine or meds come out by then. I am showing gains on Tymlos. I have side effects, but they are bearable. I do take a reduced dose. Was 4 clicks, but now 5, going to start 6 soon. Full dose is eight clicks. Before starting meds, I did weight lifting for a month and there was no improvement in P1NP or CTX. (I am not stopping weight lifting and hope that I will be able stop all meds in two years.) After three months on 4 clicks of Tymlos, I saw 90% improvement on P1NP. While a hip fracture would be unpleasant, a spine fracture and possible spinal cord injury terrifies me, so I took the meds. Do not take bisophates as the first drug. There is an order to take. https://www.youtube.com/watch Avoid Prolia. This woman reversed hers, but my doctor will not agree to HRT. https://www.youtube.com/watch

@dvcall52 Exactly! I already have one chronic pain disorder. The idea of another one from one of these drugs is terrifying.

@wilweten , honestly if I can't maintain whatever BMD I get to (in this next year on Tymlos) by keeping my routine up after stopping Tymlos, Evenity might be what I'm leaning toward. So much can change in a year, so I will start heavier research on my end in about 6 months, and hope that new studies/research come out meanwhile that can guide me. Fingers crossed!