Afib/dangers of eliquis

Posted by nitwit @nitwit, Feb 2 6:41pm

Hi
I’m a fairly healthy adult male of 73. Approximately one year ago I was diagnosed with Afib. My symptoms are rarely noticeable. I’ve never had shortness of breath, fatigue or any other Afib side effects. I have a very good cardiologist who hasn’t pushed any treatments or medications, but has however clearly informed me that going on Eliquis may be a good idea.
I’m very active and all my life have been running daily and have had no issues. All of this Afib stuff and the side effects of Eliquis are scaring the heck out of me. Just how safe is eliquis, and how likely am I to have adverse side effects from its use ?

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Everyone above laid out all the options clearly. I've been on Eliquis for probably 7 or 8 years and have never noticed any side effects. I'm 71 in a couple week, stay active, hike, backpack 2 or 3 weeks every year, have trekked to over 18,000' in Nepal, all on Eliquis.
I bang myself up quite a bit and seldom bruise; have never had any problems with excessive bleeding although I cut myself (not intentionally) probably once a month, ...or more, just keeping the house and garden maintained.

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Profile picture for marybird @marybird

I've been on Eliquis ( 5 mg twice/day) since around June of 2021, when my pacemaker remote monitor reports showed a big uptick in the number and duration of my A-fib episodes. I've had to admit I was terrified about the prospect of having to take a blood thinner, but I have had absolutely no side effects or problems with taking this drug. I don't even notice any extra bruising from taking it.

From what I've seen, and read, and this has been my experience too, that a blood thinner generally doesn't cause a person to bleed, but it will enhance, maybe prolong a bleeding episode that is caused by a cut, fall or other injury. You may notice, for instance, that if you get a minor cut on your finger, the blood may ooze for some time after it would without the blood thinner, but you can still stop it easily enough by putting a little pressure on it. That's why they caution people with A-fib who have a job or a lifestyle that puts them at more risk for falling or other injuries, to possibly consider means than blood thinners to minimize stroke risk from clotting, such as a Watchman. I do my best to avoid falls, cuts, scrapes and I'm not particularly prone to accidents, and I've had no issues at all with Eliquis.

I'd much rather have the expense and obligation of taking the Eliquis than run the risk of having a debilitating stroke that could leave me helpless and paralyzed for the remainder of my life. I have a strong family history of strokes, and I've seen several great aunts, as well as other people in health care settings who have become completely helpless and mostly immobile, not even able to do much but drool as they live out the remainder of their lives in bed or sitting in a gerry chair. My stroke risks go beyond just the risk from my paroxysmal A-fib, and I don't want to live like that. That's me, personally, others may not have such high stroke risks, and they must decide for themselves the risks versus benefits of taking blood thinners.

As for the expense of Eliquis, the price of this drug looks to have decreased significantly since the beginning of 2026. I use a manufacturer's coupon that allows me to get my Eliquis prescriptions for $10 per month supply, or $30 per 3 month supply, but I have commercial prescription drug coverage that allows that. Even still, when I looked out of curiosity at various drug plans, including Medicare drug plans, I noted that the price of Eliquis prescriptions had dropped about 30-40% since last year. I think that should come as good news to the many folks who are taking it.

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@marybird I think you represent the vast majority of people who take any medication. Life goes on as somewhat "normal".
Considering the billion plus humans on this planet there is always going to be some that suffer side effects no matter what medication they ingest or even what food they eat.
As usual when someone has a negative issue with a medication or procedure it usually becomes a headline article in the groups on FB. For that person it rightly should be but as usually happens others think "that could happen to me". Now what works very well for many becomes an issue. Think many need to realize everything we injest has a + or - effect that is unknown until after we swallow.

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Profile picture for marybird @marybird

I've been on Eliquis ( 5 mg twice/day) since around June of 2021, when my pacemaker remote monitor reports showed a big uptick in the number and duration of my A-fib episodes. I've had to admit I was terrified about the prospect of having to take a blood thinner, but I have had absolutely no side effects or problems with taking this drug. I don't even notice any extra bruising from taking it.

From what I've seen, and read, and this has been my experience too, that a blood thinner generally doesn't cause a person to bleed, but it will enhance, maybe prolong a bleeding episode that is caused by a cut, fall or other injury. You may notice, for instance, that if you get a minor cut on your finger, the blood may ooze for some time after it would without the blood thinner, but you can still stop it easily enough by putting a little pressure on it. That's why they caution people with A-fib who have a job or a lifestyle that puts them at more risk for falling or other injuries, to possibly consider means than blood thinners to minimize stroke risk from clotting, such as a Watchman. I do my best to avoid falls, cuts, scrapes and I'm not particularly prone to accidents, and I've had no issues at all with Eliquis.

I'd much rather have the expense and obligation of taking the Eliquis than run the risk of having a debilitating stroke that could leave me helpless and paralyzed for the remainder of my life. I have a strong family history of strokes, and I've seen several great aunts, as well as other people in health care settings who have become completely helpless and mostly immobile, not even able to do much but drool as they live out the remainder of their lives in bed or sitting in a gerry chair. My stroke risks go beyond just the risk from my paroxysmal A-fib, and I don't want to live like that. That's me, personally, others may not have such high stroke risks, and they must decide for themselves the risks versus benefits of taking blood thinners.

As for the expense of Eliquis, the price of this drug looks to have decreased significantly since the beginning of 2026. I use a manufacturer's coupon that allows me to get my Eliquis prescriptions for $10 per month supply, or $30 per 3 month supply, but I have commercial prescription drug coverage that allows that. Even still, when I looked out of curiosity at various drug plans, including Medicare drug plans, I noted that the price of Eliquis prescriptions had dropped about 30-40% since last year. I think that should come as good news to the many folks who are taking it.

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@marybird Elliquis goes off patent in Nov 26 so prices should drop after that

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I was diagnosed with AF (Flutter and FIB) in 2016; to ER and converted. Similar experience in 2017. A Cryoablation in 2017. AF free after two months blanking period and about 6 mos later my EP took me off Elliquis and onto 81mg aspirin. SOme minor infrequent AF episodes staring in 2021 but nothing longer than 2 hrs. Some studies suggest aspirin is not effective in preventing AF stroke so I expressed concern to EP who suggested I try 'pill in a pocket" approach and take Elliquis if episode exceeds 4 hrs. My AF symptoms are noticeable and I use Iwatch to monitor for any arrythmias. Had a lot of ectopic beats in 2024. EP said these should not concern as everyone experiences them. I was not convinced and I read that ectopic (PVCs and PACs) may be associated with paroxysmal AF. anyway EP mentioned in passing that I should check my thyroid hormone level and after lowering levothyroxine doseage the AF spells and ectopic beats have ceased. THis is my experince which may not apply to others but if you havent chased this issue I recommend you do. A couple of recent studies -OCEAN and RESULT-AF have shown that DOACs (Elliquis et al) may not not reduce stroke risk for those Post Ablation. I suggest that you read these studies and discuss with your cardiologist.

Also there's much medical opinion that one should ablate sooner rather than later as AF burden will continue to increase.There are many excellent youtube videos about ablation and new pulsed field technology is safer.

BTW, I cycle a lot and while taking Elliquis I felt sluggish and was also concerned about bike accident and bleeding so was glad to be taken off Elliquis (My Ep is also a cyclist.) I'm 77.

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I never had a problem with any blood thinner except for Plavix. I did everything while on Eliquis you can exercise and continue your active lifestyle, I just get annoyed when people scare patients considering blood thinners. I had my Watchman put in last March but had nothing to do with blood thinners, I had stroke running in my immediate family and my cardiologist suggested it. I'm still in AFIB and will always have this condition but once I came off Plavix after Watchman put in I feel no different different on or off Eliquis.

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Profile picture for chickenfarmer @chickenfarmer

I was diagnosed with AF (Flutter and FIB) in 2016; to ER and converted. Similar experience in 2017. A Cryoablation in 2017. AF free after two months blanking period and about 6 mos later my EP took me off Elliquis and onto 81mg aspirin. SOme minor infrequent AF episodes staring in 2021 but nothing longer than 2 hrs. Some studies suggest aspirin is not effective in preventing AF stroke so I expressed concern to EP who suggested I try 'pill in a pocket" approach and take Elliquis if episode exceeds 4 hrs. My AF symptoms are noticeable and I use Iwatch to monitor for any arrythmias. Had a lot of ectopic beats in 2024. EP said these should not concern as everyone experiences them. I was not convinced and I read that ectopic (PVCs and PACs) may be associated with paroxysmal AF. anyway EP mentioned in passing that I should check my thyroid hormone level and after lowering levothyroxine doseage the AF spells and ectopic beats have ceased. THis is my experince which may not apply to others but if you havent chased this issue I recommend you do. A couple of recent studies -OCEAN and RESULT-AF have shown that DOACs (Elliquis et al) may not not reduce stroke risk for those Post Ablation. I suggest that you read these studies and discuss with your cardiologist.

Also there's much medical opinion that one should ablate sooner rather than later as AF burden will continue to increase.There are many excellent youtube videos about ablation and new pulsed field technology is safer.

BTW, I cycle a lot and while taking Elliquis I felt sluggish and was also concerned about bike accident and bleeding so was glad to be taken off Elliquis (My Ep is also a cyclist.) I'm 77.

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@chickenfarmer
Thank you, for sharing your experience

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Profile picture for bubbzy5569 @bubbzy5569

I never had a problem with any blood thinner except for Plavix. I did everything while on Eliquis you can exercise and continue your active lifestyle, I just get annoyed when people scare patients considering blood thinners. I had my Watchman put in last March but had nothing to do with blood thinners, I had stroke running in my immediate family and my cardiologist suggested it. I'm still in AFIB and will always have this condition but once I came off Plavix after Watchman put in I feel no different different on or off Eliquis.

Jump to this post

@bubbzy5569
Thanks for the encouragement. Good advice.

REPLY
Profile picture for marybird @marybird

I've been on Eliquis ( 5 mg twice/day) since around June of 2021, when my pacemaker remote monitor reports showed a big uptick in the number and duration of my A-fib episodes. I've had to admit I was terrified about the prospect of having to take a blood thinner, but I have had absolutely no side effects or problems with taking this drug. I don't even notice any extra bruising from taking it.

From what I've seen, and read, and this has been my experience too, that a blood thinner generally doesn't cause a person to bleed, but it will enhance, maybe prolong a bleeding episode that is caused by a cut, fall or other injury. You may notice, for instance, that if you get a minor cut on your finger, the blood may ooze for some time after it would without the blood thinner, but you can still stop it easily enough by putting a little pressure on it. That's why they caution people with A-fib who have a job or a lifestyle that puts them at more risk for falling or other injuries, to possibly consider means than blood thinners to minimize stroke risk from clotting, such as a Watchman. I do my best to avoid falls, cuts, scrapes and I'm not particularly prone to accidents, and I've had no issues at all with Eliquis.

I'd much rather have the expense and obligation of taking the Eliquis than run the risk of having a debilitating stroke that could leave me helpless and paralyzed for the remainder of my life. I have a strong family history of strokes, and I've seen several great aunts, as well as other people in health care settings who have become completely helpless and mostly immobile, not even able to do much but drool as they live out the remainder of their lives in bed or sitting in a gerry chair. My stroke risks go beyond just the risk from my paroxysmal A-fib, and I don't want to live like that. That's me, personally, others may not have such high stroke risks, and they must decide for themselves the risks versus benefits of taking blood thinners.

As for the expense of Eliquis, the price of this drug looks to have decreased significantly since the beginning of 2026. I use a manufacturer's coupon that allows me to get my Eliquis prescriptions for $10 per month supply, or $30 per 3 month supply, but I have commercial prescription drug coverage that allows that. Even still, when I looked out of curiosity at various drug plans, including Medicare drug plans, I noted that the price of Eliquis prescriptions had dropped about 30-40% since last year. I think that should come as good news to the many folks who are taking it.

Jump to this post

@marybird I think next year there will be a generic available which I hope will drop the price.

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Been on Eliquis for 2 years now since my ablation. Some itching, and a skin spot every now and then, but otherwise fine. Worth the discomfort, I guess. CeraVe makes a good anti-itch cream. My wife slathers it on after I shower.

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Hi Eliquis users .... I've been on this blood thinner since I was diagnosed with Atrial Fib. I had an ablation last May and things seem to be going great. However, it was recommended by my electrophysiologist that I stay on Eliquis at least until my first year anniversary (May '26) at which time I wear a heart monitor for 72 hours to check to see if I register any irregular heartbeats. I was wondering if anyone on Eliquis is taking CoQ10?
It is my understanding that you have to be careful taking the supplement if you are on the older type of blood thinner i.e. Warfarin, but it won't decrease the effectiveness of Eliquis. Also, what is the recommended dose to take?

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