Advantages of Eliquis or Xarelto over Coumadin?

Posted by lgerkin @lgerkin, Feb 3, 2021

Hi - I've been on Coumadin for 15 years and my PCP and hematologist suggested I might want to try the newer generation of blood thinners. So, I started taking Eliquis last week. I haven't noticed any changes but it does make me nervous that there is no way to know for sure if my INR is at the proper level. I realize that not having to get tested once a month is great in terms of convenience and I like that I don't have to avoid foods with Vitamin K. My question is - are there other benefits to taking Eliquis over Coumadin? The higher cost isn't too much of an issue since the copay isn't too bad with my insurance.

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Profile picture for marimindy @marimindy

@chickenfarmer Hi. I’m on Eliquis for life. Please let me know what you mean by “…Elliquis goes off patent Nov 2026.”

Thanks,
M

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@marimindy I think it means that Eliquis will be able to be made generic. This has to pass the FDA though. Eliquis can be purchased in its generic form in Europe and other areas.

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Profile picture for chickenfarmer @chickenfarmer

THe patent expires thus opening up the possibility of lower cost generic. Bristol Myers has plenty of lawyers who are attempting to extend certain followon patents so things may be muddy for a while but there's the possibility of govt pressure plus PR that will be counterweights.
https://www.goodrx.com/eliquis/eliquis-generics-approved-patent-expiration-ways-to-save
Prices in other countries are more reasonable

FYI. I had ablation for AF in 2017 and after several months with no AF episodes my EP took me off Elliquis and prescribed daily 81mg aspirin. I have paroxysmal AFIB. There is also the watchman device which has shown to be effective in stroke prevention without Elliquis, Also there have been some recently published studies which show that Anticoagulants are no more effective than placebo or baby aspirin for some AF patients, I recommend that you research and discuss with your EP.

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@chickenfarmer
I appreciate your information in that it gives me (us) something to think on and check out. I’m sure the best physicians are trying to stay on top of the “latest greatest” so that they can pass it along to the patients. My personal preference is to not have to be dependent on ANY medications so will pursue more info on being eligible for ablation or the watchman device.
Also, thank you for the Canadian website. I know there’s alot of effort being made to reign in the pharmaceuticals industry.

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Lots of advantages to Eliquis from a safety and convenience standpoint. As with all drugs, some will experience side effects. A number of the folks in these forums have noted gastointestinal or muscle weakness issues.
I'm currently getting generic apixiban 5mg for $47 for 90 day supply (180 tabs) from https://canadianprescriptiondrugstore.com
I found them through https://www.pharmacychecker.com
They rate and audit foreign sources and provide a convienent search function to find the best price for a given drug.
Good luck with which ever way you and your docs decide to go.

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THe patent expires thus opening up the possibility of lower cost generic. Bristol Myers has plenty of lawyers who are attempting to extend certain followon patents so things may be muddy for a while but there's the possibility of govt pressure plus PR that will be counterweights.
https://www.goodrx.com/eliquis/eliquis-generics-approved-patent-expiration-ways-to-save
Prices in other countries are more reasonable

FYI. I had ablation for AF in 2017 and after several months with no AF episodes my EP took me off Elliquis and prescribed daily 81mg aspirin. I have paroxysmal AFIB. There is also the watchman device which has shown to be effective in stroke prevention without Elliquis, Also there have been some recently published studies which show that Anticoagulants are no more effective than placebo or baby aspirin for some AF patients, I recommend that you research and discuss with your EP.

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Profile picture for chickenfarmer @chickenfarmer

When I took Elliquis
It was something like $500 for 30 day supply but after insurance deductible my copay was around $60 for 30 days. I purchased a 30 day supply while in France in 2022, walk up price no insurance 60 euros. Just checked Trump RX but it’s not there as yet. I read that Elliquis goes off patent Nov 2026

Jump to this post

@chickenfarmer Hi. I’m on Eliquis for life. Please let me know what you mean by “…Elliquis goes off patent Nov 2026.”

Thanks,
M

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When I took Elliquis
It was something like $500 for 30 day supply but after insurance deductible my copay was around $60 for 30 days. I purchased a 30 day supply while in France in 2022, walk up price no insurance 60 euros. Just checked Trump RX but it’s not there as yet. I read that Elliquis goes off patent Nov 2026

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I was on Eliquis, doctor gave me samples. On Warfarin now. Eliquis copay is $389.

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Profile picture for CeCe1112 @cece1112

My sister bled out on the OR table during a TAVR procedure. Eliquis was new and being heavily promoted. She’d received a dose the day before her surgery. Unnecessary death. Now they say stop your Eliquis 5 days before surgery. I’m not having surgery. Just in a Rehab facility.

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@cece1112 A hematologist told me of an antidote for Eliquis: Amdexanet alfa. Most hospitals should have it on hand. Ask before going in for surgery.

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My dr. wants me to switch to Eliquis from Warfarin. My concern is my Titanium Valve. I know I can't use Xarelto with it and they seem similar. Are the restrictions the same?

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Profile picture for rubywitch67 @rubywitch67

I honestly believed I was giving up to date information about the various anticoagulants and their antidotes currently on the market.
That I gave erroneous and out of date information has left me aghast as I assume the information I gather from the Mayo Clinic, The Clevland Clinic, The University of Washington and several other well know medical centers is as up to date as it can be.
I am very sorry offering advice I had no business doing. I thought I had done adequate research, but soon learned how badly I failed in that department. I have several medical issues that I often turn to Mayo for advice and support, and I hope I may continue to do that.
With sincere apologies
rubywitch

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Don't blame yourself @rubywitch67. Harvard Health isn't very diligent in updating or throwing out information that has become obsolete, and their articles too often lack a clear indication of the date they were written. Your other sources -- Mayo Clinic, Cleveland Clinic, and University of Washington -- had no role in giving us current information on antidotes for "blood thinners" which are medically known as anticoagulants. We all can rely on Mayo, but in discussions on Mayo Connect with people anxious to find solutions to their own medical problems, we have to be alert to the possibility of being confronted with opinions, suspicions, old news. Stay with us and give us a hand on issues that are important to you. Martin

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