Developed bronchitis like cough, nasal congestion: can't stabilize

@clynnford
I started Brinsupri 25mg on 10/29/25. I was on it for 20 days and developed streptococcus pneumonia. (probably not related to Brinsupri??) I was off of it for 1 month and started back on December 17. I can't say it is helping as of yet. I am experiencing a prolonged cough after nebulizer/vest protocol. Dr. thinks it may be due to the increase of neutrophils without the Brinsupri (in other words a flare attack) So we shall see. As for my opinion, I am sceptical? But will continue and hope for the best.

Same here. The one thing that is helping is Doxycycline. And the NP didn’t give me it . So I had to text her. Why we chase them when we tell them things is so frustrating

@irenea8
No, I don't believe it is related to Brinsupri. I have frequent sinus infections. Had sinus surgery a few years ago but still have issues. Am now on Levofloxicen/budnesonide nasal rinse which seems to help.

@cdward1028 Brinsupri takes 4-6 months to achieve full benefit.

@scoop
Yes, that is what I understand...so I remain hopeful....

@cdward1028 Thanks!
I also have NTM. I’m confused about which one is causing my symptoms…..

@clynnford
I came down with type A flu on Christmas Eve (perfectly terrible timing). It was awful. Besides feeling miserable, the coughing never stopped and left me totally exhausted and out of breath. I started feeling better for a day or so, then slammed back into the continual, exhausting coughing. I got Augmentin and prednisone taper, but was still having the exhausting coughing. Went back to doc after a week and he said he thought I had inflamed my windpipe and lungs, and to stop doing the saline neb for now. (My lungs sounded clear except at the very top where coughing occurs) Gave me ipratropium/albuterol to neb every four hours as needed, started me on another prednisone taper and tessalon pearls. It has helped, but only been 2 days. I’ve also tried to suppress the cough with delays and cough drops to let things settle down.
I thought all this was interesting, since we are so encouraged neb saline all the time, so I wanted to share. I’ll report in a few days.

@sarahlynn1960 please do let me know. I’ve cut down to one saline neb (against my (NP) advice but I’m going to try going with out for a few days(shh)

@cdward1028 How has today been for you? In my own case I improved slightly again today. SO slightly tho. But I’m not getting as many cough attacks (like when u can’t stop at all. I do think in my case that the dr was right that my lungs had gotten all inflamed and needed to calm down. Has your dr give u anything else to try lately?

@sarahlynn1960 I contracted the flu approximately a year ago this month after being around too many teens who were sick and were still coming to school. I had no clue is the flu until I went to my PCP and the test came back positive for Flu A. My PCP knows my complete history about the NTM and bronchiectasis. In order for me to get some rest due to the coughing I was prescribed one small bottle of Robitussin with codeine. He and I both know that I am supposed to cough up the mucus and this was only to be used before bedtime in order to get some rest. I used it sparingly for about four days to get over the hump. I was pushing lots of caffeine free fluids. I am 77 now. It took me approximately three weeks to get well. When I finally was able to get out and about outdoors and visited with people my age at outdoor sporting events we compared notes on how the Flu A affected us. This winter I started wearing my mask earlier and have done minimal indoor events. So far so good. I don’t care if people look at me strangely in Texas that I wear a mask.