Thank you for your helpful comments. I’m so sorry you had to go through such a terrible time after Prolia injections.

Unfortunately you had to go through that. I just keep telling my doctor no, no, if you find anything natural, I'll think about it, but other natural, absolutely no.

Thank you so much for sharing this information, so helpful.
I wish the doctors recommending these meds would try them out first, and then let us know how they deal with side effect.

I’ve recently stopped Prolia after being diagnosed with Osteonecrosis and osteomyelitis of the jaw extremely painful. I was on Prolia starting in my late 40sfor 10+ years. I’m now in my 60s and Bone density improved and I was stable. I had to have surgery for bone jaw debridement. Prolia caused silent symptoms and it was unknown. And no doctors and neurologists could figure out why I was in so much pain for 6 months . Thank the Lord that my oral surgeon finally called in infectious Disease and immediately I was hospitalized was on long-term antibiotics for 30 days and received hyperbaric chamber oxygen for over 40 days. I finally recovered but dropped 20 pound and months to recover.. But now I cannot go on any other bone density drugs. My endocrinologist started me on estrogen and progesterone to support some bone strength so far. I’ve been off Prolia for a little over two years. Without fractures. I just started stength training again Such a long painful recovery. There are other ways to support . Check out https://melioguide.com/
I just wish doctors would have shared and educated me as well back then there was no warning labels for jaw problems. Now every commercial and labels warn you of this serious side effect. Please educate yourself before starting this drug.

@me75 never heard of that. My friends & I have been on
Prolia for over 2 yrs. No side effects.

@me75
I’ve been getting Prolia injections about 5 times now since 2023, every 6 months. My DEXA scores seemed to improve some until the 2025 DEXA Scan. A few months ago I had blisters on my gums and swelling really bad and bleeding if I pressed on the gums. It was so painful, I couldn’t eat solid food.
I had Cancer dx in 2020, already dx with osteoporosis but nothing meds for Osteoporosis because I got a Stem cell transplant. With a SCT a patient can get GVHD (graft versus host disease) which can be a severe rash and other problems like mouth sores. GVHD Mouth sores were ruled out. I saw an Oral Surgeon, got mouth trays (mouthplates) made to hold medication on my gums. The treatment helped and got rid of any mouth sores and gum tenderness. I’m wondering now if they didn’t know or consider that side effects from Prolia might have been the cause. I take extra care of my oral hygiene since having that problem. Now I’m having some discomfort in my gums around my wisdom teeth. I’m sure I need some dental extractions from past root canals but due to my platelets being too low , I can’t have any procedures or surgeries because of severe bleeding. My remedy clove oil +coconut oil. Any suggestions or advice or sympathy (ha ha) would be welcome.

@me75
Well, that cinches it for me! I had decided against Prolia because I had learned that if you stop taking it, you lose all progress you have made. I'm not going to take a drug like this that I would have to stay on forever. No bisphosphonates for me after seeing a friend of my Mom's go through the jaw necrosis. Took Tymlos, but got a big kidney stone from that (no thanks!!). Not many options left, I guess. I'm starting to feel like all of these meds are a bunch of BS - no offense intended to anyone. Thank you for sharing your experience!