Hi @rubyjag3 Thank you for the update! Wow, your Serum B-12 numbers have sure escalated since last September when they were 6,000! Now they’re over 22,000. Since I read your post earlier this afternoon I’ve been scouring Google Scholar for articles relating to very high levels and potential causes.
From everything I’m reading this is exceptionally high and doctors should be focused on tracking down the reason. Telling you that it is of no concern is not an answer. Something is causing this to happen.

From my understanding, sometimes there can be a genetic defect which can cause the body to have high levels of homocysteine and low levels of folate where your body isn’t able to process Vit B 12, actually creating a Vit B 12 deficiency in the body. Have you had a MTHFR gene test run?
In this article on the mutation it mentions glaucoma as a potential side effect.
~What is an MTHFR mutation?
https://www.medicalnewstoday.com/articles/326181
Do you remember your doctor ever running a test to check for Folate and Homocysteine levels in your blood?
Have you been told you’re anemic?
Has your thyroid function been tested?

Because you have your blood work check routinely, I’m sure this would already have been discussed, but have you been told you have a myeloproliferative blood disorder meaning the the bone marrow isn’t able to produce normal blood cells? That would be indicated by either too many or too few of any one particular blood product such as Red Blood Cells, White blood cells or platelets. The shape and size of your red blood cells would also be in the blood report.

Here’s one of the articles I was talking about where there have been studies of patients who have myeloproliferative disorders with High Vit B 12 actually masking their low vitamin level.
~~~
~Does an Elevated Serum Vitamin B12 Level Mask Actual Vitamin B12 Deficiency in Myeloproliferative Disorders?
https://www.sciencedirect.com/science/article/abs/pii/S2152265012000092
~~~~

Again, I’m not a doctor and in no way trying to diagnose your condition. But I really hope you can find a doctor who takes this seriously and get to the bottom of your symptoms…some of which are on the list of a vitamin B-12 deficiency. Have you seen a hematologist yet?