As promised, my successful tapering off Effexor (Venlafaxine)

Posted by sheffieldsmith @sheffieldsmith, May 31, 2020

Below you will find the tapering plan that I used to successfully wean myself off Effexor (Venlafaxine). Feel free to share this with your doctor If you would like. I researched and came up with this plan, which was approved by my doctor, although she thought I could probably have weaned myself off sooner. But the reality is that we all have differing tolerance levels for tapering and weaning off this powerful drug from our bodies. Some people can taper faster, but usually not those who have been on this drug for years (like myself, since October 2002). I tapered off EffexorXR 150mg capsules about 5 years ago down to 75mg, and was on that maintenance dosage for a couple of years until I started weaning off the 75mg a year ago in April 2019. As of October, 2029, I’ve been withdrawal symptom free, but I still have occasional periods of anxiety when triggered. But I realize these waves of anxiety will soon pass, and I cope by deep breathing, taking a walk, having a cup of chamomile tea, etc. Cutting my exposure to watching upsetting news has really helped a lot as well. These days I seek things that bring joy and peace in such a turbulent world. Wishing you all a successful weaning off this powerful drug.

Weaning off Venlafaxine XR 75mg (Effexor-(extended release)capsules:
Weaning plan off plan that worked for BSS:
1. Inform your doctor you are tapering down from 75 mg Venlafaxine and ask them to prescribe 37.50 tabs to help with tapering doses (1/2 dosage down from 75 mg Venlafaxine capsules). The tabs are easier to cut into halves and quarter dosages than counting out beads from the capsules.
2. Begin your taper only after you are on a non-withdrawal symptomatic dosage level. If you were having w/d symptoms at 75 mg, you’ll need to go back to the level at which you were symptomless and stay there for 2-3 weeks before deceasing to a slow taper. NOTE: after successfully tapering from 150mg Venlafaxine down to 75mg for a month, I was unable to tolerate a drop cold turkey from a daily dosage of 75mg down to 37.50mg (50%) without having bothersome withdrawal symptoms of dizziness, brain fog, brain zaps, and nausea. So after researching various tapering plans, I came up with a slower tapering schedule my body could tolerate to finish the tapering from 75mg to 37.50mg, and then on to complete the tapering. Your body may even need slower tapering, so adjust according.
3. Week 1-2: Take 75mg caps MWFSu; take 37.50mg tab on alternate days Tu,Th, Sa. At the end of week 2, if you only have relatively mild to no withdrawal symptoms, proceed to week 3. IMPORTANT: If you have intolerable symptoms, adjust to a slower tapering schedule by adding an additional 1/2 tab on the alternate days (or take a total of one and a half 37.50 tabs on alternate days). You’ll then have to tweak the rest of your tapering schedule. If all goes well, proceed with week 3.
4. Week 3-4: Cut a few 37.50 tabs in half with a pill cutter or exacto knife blade to create quarter pieces. Take 37.50mg tab on MWFSu and take 3/4 tab on alternate days Tu, Th, Sa.
5. Week 5-6: Take 3/4 of a tab MWFSu, and take 1/2 tab on alternate days Tu, Th, Sa. If only mild symptoms, proceed to week 5.
6. Week 7-8: Take 1/2 tab on MWFSu; and take 1/4 tab on alternate days Tu, Th, Sa. If no symptoms, continue to week 7.
7. Week 9-10: Take 1/4 tab on MWFSu; and take 1/8 tab (cut 1/4 tabs in half) on alternate days Tu, Th, Sa. *Notice the quartering of doses into crumbs now...very important to keep small dosage tapering to remain withdrawal symptom free.
8. Week 11-12: Take 1/8 tab crumb on MWFSu; take none on alternate days Tu, Th, Sa. *If skipping alternate days produces symptoms, stay on 1/8 tab crumbs for a couple of weeks before alternating skip days for a couple of weeks.
You’ll find that this schedule may have to be tweaked for you by extending the time you stay on a taper...possibly up to 3-4 weeks before beginning a new tapering down. It all depends on how you tolerate the first two weeks.

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Profile picture for mbryan @mbryan

That makes a lot of sense! That's good that they are not prescribing it any more.

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My doctor isn’t but I’m sure others are still prescribing. They haven’t been taken off the market.

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Profile picture for cfos @cfos

I tapered off Effexor several years back. I had a horrible time and thought I was losing my mind. I went on celexa for a few years only to start cymbalta two years ago. Never felt well on any of them and now tapering off cymbalta. It’s not going well. I listened to a talk by a man who had an easier time coming cocaine than coming off antidepressants.

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I don’t think cocaine has a long drawn out withdrawal.

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Profile picture for cfos @cfos

I tapered off Effexor several years back. I had a horrible time and thought I was losing my mind. I went on celexa for a few years only to start cymbalta two years ago. Never felt well on any of them and now tapering off cymbalta. It’s not going well. I listened to a talk by a man who had an easier time coming cocaine than coming off antidepressants.

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I'm sorry to hear that, what a crazy ride! I have started to feel so much better after figuring out what the withdrawals cause. I'm able to treat my self with the ride foods and natural supplements to aid in this recovery. Effexor and SSRN's make your cortisol sky rocket. Cortisol is you stress hormone, therefore, glucose levels can also rise. While the stress hormone causes you to panic, some soothe that panic with eating, and that's exactly how my body responds. I would do some research on cortisol levels and make sure to meditate and do calming activities that can help you cortisol levels to get back to normal!

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Profile picture for sears @sears

My doctor isn’t but I’m sure others are still prescribing. They haven’t been taken off the market.

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I think that this drug is being advertised as the wrong kind of medicine. It's so dangerous for the human body.

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Profile picture for sears @sears

I don’t think cocaine has a long drawn out withdrawal.

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It doesn't, but whatever chemical is in Effexor/Venlafaxine is highly addictive to the body, more addictive to the human body than cocaine or heroin.

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Profile picture for mbryan @mbryan

I'm sorry to hear that, what a crazy ride! I have started to feel so much better after figuring out what the withdrawals cause. I'm able to treat my self with the ride foods and natural supplements to aid in this recovery. Effexor and SSRN's make your cortisol sky rocket. Cortisol is you stress hormone, therefore, glucose levels can also rise. While the stress hormone causes you to panic, some soothe that panic with eating, and that's exactly how my body responds. I would do some research on cortisol levels and make sure to meditate and do calming activities that can help you cortisol levels to get back to normal!

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Thanks for your suggestions. I’m so tired. Today I’m also edgy. Makes that cortisol theory spot on. Have you finished your taper? And off Effexor ? Have you found foods which help?

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Profile picture for mbryan @mbryan

Yes, that's what I heard as well. I don't think that I tapered off of my medicine correctly because I am having some bad withdrawal symptoms right now.

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I see you are still not off completely. Ignore my other question. Would you mind describing your withdrawal symptoms?

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Profile picture for mbryan @mbryan

I am having trouble staying full/feeling full/feeling constantly hungry. I need some advice on what to eat. Is this a serotonin problem that the medication causes as a withdrawal symptom? Has anyone else also gotten off of this medication?

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I’m on day 3 of cold Turkey of 75mg venlafaxine. I forgot my meds at home and I am 2.5 hours away. Major brain zaps! They pulse right from my head to my toes hundreds of times a minute then subside for a few minutes. And over and over again. I started taking this drug for hot flashes from menopause. No help. Would never have begun knowing how hard it is to come off. I think Tumeric helps me perhaps. Heck I don’t know. Feel crappy!!!!

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Profile picture for cfos @cfos

Thanks for your suggestions. I’m so tired. Today I’m also edgy. Makes that cortisol theory spot on. Have you finished your taper? And off Effexor ? Have you found foods which help?

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Yes, I have finished my taper and am completely off of meds and it honestly is great. Food that helps are ones high in magnesium including spinach and leafy greens (I have eaten spinach and veggies every single day once I found out my cortisol levels were high). Cinnamon, dark chocolate (try to find w/no sugar), broccoli, seeds (I eat chia seeds and flax seeds everyday), nuts, olive oil, and probiotics (could be a probiotic supplement taken daily). I also eat berries, oranges, ginger and drink green tea to help lower my glucose levels since cortisol also causes you glucose levels to rise!

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Profile picture for brendaloukes @brendaloukes

I’m on day 3 of cold Turkey of 75mg venlafaxine. I forgot my meds at home and I am 2.5 hours away. Major brain zaps! They pulse right from my head to my toes hundreds of times a minute then subside for a few minutes. And over and over again. I started taking this drug for hot flashes from menopause. No help. Would never have begun knowing how hard it is to come off. I think Tumeric helps me perhaps. Heck I don’t know. Feel crappy!!!!

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I have heard that they are starting to give this medicine to women with menopause, and that is not the right move. This medicine is not used to treat any sort of bodily function like that at all. If I were you, I would slowly taper off and look into supplements that help with hormone imbalances. My withdrawal symptoms were quite like having menopause which was odd because I'm 25. I started to take Happy Mammoth Hormone Harmony supplements and they helped so much with the process because I found out that my cortisol levels were really high whilst on the medicine and once getting off the medicine. It's' worth it to research ways to lower your cortisol levels as well because this medicine heightens those stress hormones!

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