Rare serious side effect of Eliquis: Muscle weakness

YOU GOT MY ATTENTION {dance 4life}.. Could you advise me "WHERE" you got this Brain Hemorrhage info from ? It sounds very scary. Since I was just given Eloquis 25mg twice a day , I am very concerned with your post . Would like more info before confronting my Heart Dr. If this info is correct , whatever Big Pharma that makes this med. is lining itself up for "LAWSUIT CITY" !! If I were you I would definitely talk to a MEDICAL MALPRACTICE ATTY. "BEFORE" the "CLASS ACTION VULTURES" start their PR program recruiting clients that will end up with "NOTHING" while the Attys get rich . That's how CLASS ACTION " works . I been in 3 of them . Attys. got Millions I got $6 on one $12 and $7 on the others . Maybe others on here did better . Remember Serzone . a Med for Depression . It was quickly taken off market when bad stuff happened . Now my PAIN DR. tells me it's back under another "LABEL" /NAME " . Big PHARMA is a "LEGAL MAFIA " nothing more . ! My Opinion . I look forward to your info source . Thanks and Best Wishes .. Junqdawg

[I did have one very short telehealth virtual call.  I haven driven a vehicle in over 30 years so my husband takes me to appointments.  I now have six doctors who work together:  cancer, hematologist, cardiac, spine, surgeons, gastroenterologist.]
After my first post here I was back in the hospital again the first week of April via ambulance (I didn't realize my husband called them because I was barely aware).  This time I was put through a variety of tests for a full week, given 4 blood transfusions along with two other medical transfusions at the same time (I had three intravenous lines).  I had an endoscopy and colonoscopy done simultaneously along with a medical stress test for my heart and blood clotting test was also done that continued to show clots.  I had to have blood draws every four hours.  My own blood could not gather or transport enough oxygen and I was actually losing blood so they searched for 'bleeding' but none could be found so another test to look at my small intestine will be done.  (Vitamin B12 was not an issue at all)  Over the course of a week I averaged 1-1/2 hour of sleep a night, which is common in hospitals when there are issues that have to be tested constantly.  It was found that I have Gerd, a hiatal hernia but my colon is fine except for hemorrhoids.  This anemia would have eventually caused death
Two weeks later I had a scheduled lung biopsy done because over the course of the 4-1/2 months I'd been told, after a number of earlier tests, that a nodule in one lung was cancer so I had a number of visits for this.  However, the robotic biopsy result said it was NOT cancer after the surgeon had them test another piece of the nodule again.  Thankfully whatever it is the surgeon removed it without taking out the lung lobe where it was located.  The nodule pieces were sent to a lab to investigate what it is.  I have an appointment to see the surgeon today after a chest x-ray this week and maybe I'll know more.
I have more energy now (I think the blood transfusions made a HUGE difference); I have an appetite and am eating; I no longer have dry-burning mouth and lips and I have SPIT!; I am now actually walking each day OUTSIDE with a Tall Walker so I can stand up straight and breathe.  

I'm back on Eliquis, and medication for Gerd and am feeling a lot stronger and better.  

@hulitoons, I'm so glad to hear that the blood transfusions have helped so dramatically. Wow, you're out walking, enjoying the outdoors and feeling stonger and better. That's good on so many levels.

My husband was on Eliquis for 7-8 weeks and suffered two collapse of legs resulting in two serious falls. Waiting on results from heart monitor for AFIB results in meantime doctor stopped Eliquis.

Hi @ewilson and welcome to Mayo Clinic Connect. Glad you were able to find up. Sorry to hear about about your husbands falls. Did the doctor take him off for precautionary reasons or because he thought Eliquis was the primary cause in the muscle weakness that caused the falls?

I have been having test after test. I had triple bypass two years ago. I have not been right ever since. I can hardly walk, tire very easily. Started to have incontinence, swelling in legs, thigh area, this is just some of the things that have changed my life.I am now on a water pill which did not work before and I have lost all faith in the medical community. All my very best to you.

Hi, I have been reading your thread and am concerned my Mum may be suffering from muscle weakness due to Apixaben. She has gone from walking 8 miles a day at age 75 to not being able to walk 30 yards. She has been on Apixaban for a year and the doctor says its unlikely its that as the side effects would have happened very soon after going on it.
If you dont mind, please could you share how you are now that you have stopped taking the Eliquis? I am very hopeful that she will get better if we change her medication and would be grateful to hear your story after February, I hope that you did get better.

I started eliquis in April after a kidney clot - over the summer, I got progressive pain in calves and thighs and my ability to walk has been affected. Dizzy and unstable

I've been on Eliquis about 3 years. I hadild dizziness before then, but it's gotten progressively worse. Pain in right quadricep is new, and legs are weaker. I've had both knees and hips replaced over past 5 years. So my issues are complex, admittedly, but the dizziness is maddening. Am I overdoing the PT? No one seems to have any answers.

My sister is a pharmacist and said that eliquis can cause dizziness. She had a patient reduce dosage (obviously after consulting her doctor) and the dizziness went away.