B-6 vitamin danger!

According to this article drink lots of water - "Drink water to help flush excess vitamin B6 from the body. Since this compound is water-soluble, urine is the primary means of excretion, according to Memorial Sloan-Kettering Cancer Center. Typically, it takes the body between 15 and 25 days to eliminate unused pyridoxine. Drink eight, 8-oz. glasses of water per day as part of a healthy diet." --- How to Lower B6: https://www.livestrong.com/article/522968-how-to-lower-b6/

Does your colleague drink energy drinks? They are normally notoriusly high in B6.

Ive had heart scan and my ct score is 653.statins recommended. With baby aspirin. Will the painful nuropathy decrease with lower chloresterol and are statins the only alternatives

Hi @neasrenrut and welcome to Mayo Clinic Connect. You will see that I moved your post to a discussion that talks about calcium, B-6, neuropathy issues. I did this so you can connect with members going through similar scenarios.

What prompted the heart scan?

High serum chlesterol number and prevailing nueroathy in feet and hands. A friend A retired md brought another calcium issue that id caused by prolonged inactivity. Hypercalcimia. I was bef ridden for nearly a tear!

Where did you move me to? The way!

I need Hepl Any One Know How To Stop My Neurophy pain at night

There is a strong possibility that the neuropathy pain will increase with the statins. Beware

Hi @neasrenrut, I would like to add my welcome to Connect along with @amandaburnett and other members. Your post was moved to this neuropathy discussion that has posts about calcium, B-6, neuropathy issues - B-6 vitamin danger!: https://connect.mayoclinic.org/discussion/b-6-vitamin-danger/

There is also another discussion that might be helpful
-- Calcium Scan: https://connect.mayoclinic.org/discussion/calcium-scan/

You mentioned your CT scan was 653. Here are a couple of references that maybe helpful with information related to your CT scan results:

--- "Over 400 Extensive evidence of CAD" Cardiac CT for Calcium Scoring: https://www.radiologyinfo.org/en/info/ct_calscoring
--- "The multivariate analysis revealed that the presence of CAD was a statistically significant risk factor for ischemic peripheral neuropathy." -- Prevalence and Risk Factors for the Peripheral Neuropathy in Patients with Peripheral Arterial Occlusive Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480317/

I'm not a doctor and have no medical training but I'm not sure anyone can answer your first question will the painful neuropathy decrease with lower cholesterol numbers but my guess is that it would take more than lowering the cholesterol numbers. Your second question is really a good and one you should discuss with your doctor. My doctor has wanted me on statins for a long time but I'm not about to start them because I have neuropathy and do not want to make it worse. I might think differently if I had a condition that would put me in a higher risk. Then I would have to weigh my options and discuss with my doctor. There are things you can do to lower cholesterol naturally but you really have to work at it. Mayo Clinic has a good place to start - https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/reduce-cholesterol/art-20045935

Are you on any treatments for your Hypercalcemia?

Welcome @timcryan, I'm sorry to hear you are having more neuropathy pain at night. I'm wondering if you might find this discussion helpful -- Neuropathy Pain at Night: What helps?: https://connect.mayoclinic.org/discussion/night-pain-2/

Is the pain mostly in your feet and legs?

Greetings @timcryan, and welcome to Connect. This is a group of patients and caregivers who help others with quality of life issues. I would absolutely call nighttime Neuropathy pain something that can impact your quality of life. It can also make you sleep-deprived. So let's have a look. First of all, how long have you had neuropathy? Have you been diagnosed? And has that diagnosis included a skin test biopsy?

I have had SFN small fiber neuropathy for a number of years. Mine is related to trauma accidents and surgeries over the last 50 years. Ever since trying medical cannabis for the pain and tingling and numbness of SFN, I have been able to sleep pretty well. I use a dropper of a CBD/THC tincture that I take before bedtime. Mine happens to be a 2:1 mixture of CBD and THC. Within about 20 minutes I wander off to sleep and wake up refreshed in the morning.

What have you tried? I am not good with opioids or OTC medications. My PCP is very supportive and together we evaluate and plan my daily routine. Because I succumb to anxiety quite easily I also use Duloxetine in the morning to take the edge off the anxiety that can create pain.

In addition to tinctures, I use a CBD:THC topical for both acute and chronic pain.

I am going to have to have some more information from you so that I can refine these suggestions to make them provide the greatest support.

Where on your body is the neuropathy pain the worst?
May you be free of suffering and the causes of suffering.
Chris