Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)

Posted by richyrich @richyrich, Nov 2, 2016

I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you

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@jakedduck1

@huxy
You mentioned taking half your dose. I wouldn’t reduce your medication by 50% or anywhere near that much. You have to go slow. You have taken this drug for a long time and that plays a part in how long you need to taper. There is no one formula for tapering so going slow is you best chance of not having any withdrawals. Don’t be in a hurry. Even a long taper would be short compared to how long you’ve taken it. I believe you’ll regret cutting your medication in half especially as your dose decreases. Are you currently having any withdrawal symptoms?
Take care,
Jake

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Thank you Jake!
I agree with you. I may have not been clear. I reduced my pills by a quarter. From 2 tabs to 1 1/2 then 1 1/4 (both for three weeks). After I finish the 1 1/4 tabs I plan to go to 1 tablet.
Thank you for your input. Believe me when I say it is hard enough reducing by this amount! I’d hate to go any faster.

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@huxy
“Believe me when I say it is hard enough reducing by this amount! I’d hate to go any faster.”
How about going a little slower and making it easier.
I went off several medications so slowly I never had any symptoms at all.
You decreased your dose by about 25%, which is high. You say it’s “hard” that would indicate to me your tapering to fast.
There is a tappering method known as the 5-10% taper. It’s best if it’s done through a compounding pharmacy. Large tapers are better tolerated in the beginning but as your dose decreases if your taper isn’t adjusted withdrawal symptoms are more likely to occur.
Jake

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@jakedduck1

@huxy
“Believe me when I say it is hard enough reducing by this amount! I’d hate to go any faster.”
How about going a little slower and making it easier.
I went off several medications so slowly I never had any symptoms at all.
You decreased your dose by about 25%, which is high. You say it’s “hard” that would indicate to me your tapering to fast.
There is a tappering method known as the 5-10% taper. It’s best if it’s done through a compounding pharmacy. Large tapers are better tolerated in the beginning but as your dose decreases if your taper isn’t adjusted withdrawal symptoms are more likely to occur.
Jake

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Thank you Jake! Really great advise/information.
Huxy

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@huxy

I’m down to 37.5mg once a day and a 1/4 crumb once a day. This has taken one month of gradually reducing my prescription.
Anyone else trying to get off of Effexor ?

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I'm off. Its hell going through. Please know you are not alone. There will be light in the world again, but it may take awhile.

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@sherry47

I'm off. Its hell going through. Please know you are not alone. There will be light in the world again, but it may take awhile.

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Thank you so much for your words of encouragement! No nausea today and plenty of happy energy. So different from yesterday.
I’ve Got to keep on going!
Thank you

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@bud123

Thank love for this informative article!

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Thank you for your tips! The struggle is real!

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I started tapering at 300mgs. 1 month at 150, one month at 75, one month at 37.5, stop. I thought l was going to die. I wanted to die. I postponed my final college degree module, cried, contemplated suicide, you name it. Too many doctors don't seem to know anything about tapering, because l could easily have killed myself to escape the pain.
I survived, but knew very little about what to expect, because neither did any of the experts responsible for my care. I was asked what l wanted to try. I AM NOT A DOCTOR. But l'm staying clean. I am not becoming a statistic. I am a bpd survivor.

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I have been tapering down from 150 mg of Effexor after several weeks at 37.5 mg., I am now on day three of not taking it at all. I’ve been managing the achy body with Tylenol all through the tapering. However, now I am experiencing insomnia and then when I finally fall asleep from exhaustion, I have crazy and slightly disturbing dreams so I wake up pretty anxious. That part is manageable. I am really struggling with the “swooshing” sounds in my brain. They are not painful but make is extremely difficult to concentrate and focus on computer work for my job. Also I am feeling nauseous so my brain wants me to eat all the time. Plus, I feel pretty weepy at times and get irritated easily. Any tips to get through this time? I know eating healthier and continue to exercise will help. Any other tips? Especially with the “swooshing” sound in my head? I am also considering taking Tylenol PM at night so I can fall asleep and stay asleep. Any advice on this plan? Thank you!

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@adanaya

I started tapering at 300mgs. 1 month at 150, one month at 75, one month at 37.5, stop. I thought l was going to die. I wanted to die. I postponed my final college degree module, cried, contemplated suicide, you name it. Too many doctors don't seem to know anything about tapering, because l could easily have killed myself to escape the pain.
I survived, but knew very little about what to expect, because neither did any of the experts responsible for my care. I was asked what l wanted to try. I AM NOT A DOCTOR. But l'm staying clean. I am not becoming a statistic. I am a bpd survivor.

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Hi @adanaya and welcome to Mayo Clinic Connect. You are quite brave to endure that! My goodness I cannot imagine the pain and suffering.

Here is an article on self care with BPD:
https://www.mind.org.uk/information-support/types-of-mental-health-problems/borderline-personality-disorder-bpd/self-care-for-bpd/

What are you currently doing to fight the mood swings and the ups and downs?

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@seabrook22

I have been tapering down from 150 mg of Effexor after several weeks at 37.5 mg., I am now on day three of not taking it at all. I’ve been managing the achy body with Tylenol all through the tapering. However, now I am experiencing insomnia and then when I finally fall asleep from exhaustion, I have crazy and slightly disturbing dreams so I wake up pretty anxious. That part is manageable. I am really struggling with the “swooshing” sounds in my brain. They are not painful but make is extremely difficult to concentrate and focus on computer work for my job. Also I am feeling nauseous so my brain wants me to eat all the time. Plus, I feel pretty weepy at times and get irritated easily. Any tips to get through this time? I know eating healthier and continue to exercise will help. Any other tips? Especially with the “swooshing” sound in my head? I am also considering taking Tylenol PM at night so I can fall asleep and stay asleep. Any advice on this plan? Thank you!

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Talking books.

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