Is the Vaccine safe for someone who has the MTHFR mutation?

I discussed with my doctor and she had no interest in listening to my concerns so a pro/con list was never made. Think it's time to find a new doctor 🤔 Her only feedback was to get Pfizer. Thanks for the reading material and quick response. I'll look into this!

I've had both vaccinations anf just got my booster yesterday

I'm homogeneous c677t
I got Pfizer

Welcome @forestguide. Are you indeed a guide of forests? I love the username.

May I ask what led to your discovering you have the homozygous C677T MTHFR gene mutation?

Thank you! So far no side effects?

Sore arm and bitchy is all the symptoms for two days

Yes, I am a certified Forest Bathing Guide! I did the 23 n me and then turned that to genetic genie for the results

I also have the MTHFR mutation (compound heterozygous) and have had issues with blood clots and a myriad of symptoms arising from it including transient vision loss. I just want to say that about 40% of the population have ONE heterozygous mutation and that those ONE (heterozygous) mutations ‘usually’ do not cause any harm to the people who carry them, dependent on the allele mutated. In order for MTHFR to affect you, you will need to be a compound heterozygous or homozygous. This is what science is backing currently, albeit, it can change since this is not a thoroughly studied area. They have recently found that there are more than two possible mutations for MTHFR, but this is also new science and not currently well understood. So, yes, the above commenter who states that out of 350 million people vaccinated there were only 500,000 reports in VAERS of adverse events. We have no idea how many of these patients had MTHFR, if at all, or individuals with only one heterozygous mutation that would not have any concern for negative outcomes. The largest question is: how many people have gotten the vaccine who are compound heterozygous or homozygous? That is where the real danger lies for those with MTHFR. I am pro science and pro vaccine and inquired about the Pfizer, but my physician and I have discussed this and she also feels a medical exemption would be necessary for now. It boils down to this: if you have had problems with clotting and issues related to MTHFR (compound heterozygous or homozygous), then it is highly likely that clots or complications will form because of COVID infection and even possibly from vaccination. We do not know much info about the vaccine and how patients with these mutations will be affected. My guess is that not many people who know that they are MTHFR compound heterozygous or homozygous and has had prior complications have gotten the vaccine. I’m hoping that research can help us determine a way to mitigate adverse effects to receive it safely. Also, the C677T mutation and complications/mortality with COVID was more relative to those of Latino decent.

Hi everyone, I have the MTHFR mutation and was vaccinated in early January and early February (Moderna). I have had no side effects. My 22-year-old son & 13-year-old daughter (MTHFR status unknown) were both immunized without issue (daughter had Pfizer). Now, 19-year-old daughter with MTHFR is about to go get vaccinated. With the increased risk of death from COVID due to MTHFR, this was an easy call for me.

I have Mthfr (A and C). I took Moderna. Had side effects with second dose for 24 hours. After that I am fine.
I do have a question: my granddaughter (33) has mthfr; she contacted covid and had severe symptoms for two weeks, no hospital, and recovered. I want her to take one dose of vaccine but she is refusing. What can in say to convince her it is safe to take it?