New Study Reveals DANGER for immunocompromised.

Posted by lizzy102 @lizzy102, Aug 21, 2021

New England Jorurnal of Medicine: to paraphrase, 55% of those hospitalized nationwide with breakthrough Covid infections are immunocompromised. Delta Variant. I am taking super precautions!! Please be excruciatingly careful about your safety out there folks.

Interested in more discussions like this? Go to the Transplants Support Group.

@athenalee

Lori, there are many more people like your friends that are now getting Covid. Covid roulette is definitely risky and deadly. I’ve heard some researchers say that the Delta variant might bring us to community immunity because so many people will be infected and many will die. A scary dystopia that could be avoided. But sadly I don’t have much faith in people these days.

Jump to this post

People have proven to be a disappointment. 🙄

REPLY

On the brighter side, now that I have vented that, I don’t feel angry about it anymore, just very determined to protect my tiny family.

REPLY
@tjdog

Stats are showing that the fully vaccinated are likely to only have mild symptoms, if any, if they get breakthrough covid. What about people who are immunosuppressed? I have received 3 doses of Moderna. I was negative for antibodies after the first 2. Haven’t been tested yet after the 3rd. Can the vaccine itself prevent serious complications, or do you need to have developed the antibodies.

Jump to this post

@tjdog, you ask a good question. "What about people who are immunosuppressed? Can the vaccine itself prevent serious complications, or do you need to have developed the antibodies?"

You'll notice that I moved your question to this existing discussion in the Transplants group where fellow members @athenalee @lizzy102 @gingerw @loribmt @rosemarya @mollyv @auntieoakley and others are also talking about this.

I think this article may be of interest to everyone in this discussion:
Mayo Clinic expert discusses breakthrough COVID-19 cases https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-expert-discusses-breakthrough-covid-19-cases/

August 13, 2021 from Mayo Clinic
"COVID-19 vaccines remain the best defense against COVID-19. However, no vaccines are 100% effective at preventing illness in vaccinated people, and a small percentage of breakthrough cases are expected, according to the Centers for Disease Control and Prevention (CDC). Breakthrough COVID-19 cases are receiving a lot of attention, but they are not what's driving the current surge."

TJ, I hope you develop some antibodies with the 3rd dose. Until then, we have to hope fellow citizens will continue to get vaccinated. As always, keep up with practising all the recommended precautions of masking, distancing and hand washing.

REPLY
@athenalee

I’ve done extensive research into herbs, supplements, etc. metabolized by the CYP3A pathways and which would therefore interact with Tacrolimus and Cyclosporine. I’ve only found one reference, attached, which does list oregano along with other “pungent spices,” if taken in large amounts.

But, if you really look at everything that is metabolized by CYP3A enzymes, we wouldn’t be enjoying most teas, coffee, soy, pepper, and a host of other things. Substances do vary in their interaction level due to strength, if they’re metabolized by both CYP3A4 & CYP3A5 (as with Tac and Cyclosporine), how much they’re processed by the liver, etc. So, since I was told coffee and tea is ok in moderation, I do have my half cup of coffee each morning!

I no longer take the oral oil of oregano tincture, as it’s, of course, concentrated. I do use 1 drop as a mouth wash to control oral thrush and the occasional skirt of SinuOrega nasal spray.

Happy travels JK!

Jump to this post

@athenalee You have obviously researched this well. I was thinking it might be similar to Airborne and another OTC product that people use when flying to improve their immunity. Apparently SinuOrega is a very different product than those.

@loribmt It's really terrible that our country and families have become so divided on this issue. Fortunately all of our families have gotten vaccinated, and all of our close friends but I will no longer use the nail tech that I used to go to because she will not get vaccinated, nor will I use the house cleaner who I had every other week. Both of them were very good so I do miss them.

We will not socialize with non-vaccinated people, nor will eat inside of a restaurant, and even after having my third shot I am quite sure we will continue that. Frankly, we are old so at greater risk. People at any age can get a serious case and have long lingering effects but at my age and my husband's age, it could be a real problem.
JK

REPLY
@athenalee

Now that the Pfizer vaccine has FDA approval a lot of businesses and institutions will be mandating their employees get vaccinated. Of course many will still evade these mandates with falsified documents, but hopefully it will have some impact. In my town of 12,000 the mask mandate was reinstated last week for indoors anyway. So, this is certainly helpful. Our governor still has his weekly Covid press conference, aired statewide. It is indeed so foolish that protecting everyone’s health has become political in a time when our country and world face such a dire pandemic.

Jump to this post

Hello I noticed that your husband has had stem cell treatment. I have been dx with MCD. If my current condition doesn’t respond appropriately to Tacrolimus I am considering researching Stem Cell options. What is his dx and how successful was the stem cell treatment? Thank you for sharing information

REPLY
@codered032

Hello I noticed that your husband has had stem cell treatment. I have been dx with MCD. If my current condition doesn’t respond appropriately to Tacrolimus I am considering researching Stem Cell options. What is his dx and how successful was the stem cell treatment? Thank you for sharing information

Jump to this post

I don’t k ow if his was directed at @athenalee or myself but my husband has multiple myeloma.

REPLY
@auntieoakley

I don’t k ow if his was directed at @athenalee or myself but my husband has multiple myeloma.

Jump to this post

From codered032 Sorry I am still learning to navigate the site. I just noticed that your husband had two stem cell treatments. I assumed they were kidney issues, but it appears that this was for another condition. I am exploring regenerative treatment for my kidney disease.

REPLY
@codered032

From codered032 Sorry I am still learning to navigate the site. I just noticed that your husband had two stem cell treatments. I assumed they were kidney issues, but it appears that this was for another condition. I am exploring regenerative treatment for my kidney disease.

Jump to this post

Hello @codered032 Welcome to Connect. Don’t worry, we’ve all made user “mistakes,” but you’ll get the hang of it. There’s handy tip info, including - https://connect.mayoclinic.org/blog/about-connect/newsfeed-post/how-to-comment-reply-like-bookmark-and-more/

REPLY
@loribmt

People have proven to be a disappointment. 🙄

Jump to this post

I agree. But I know you’ll continue to inspire with your bubbly cheerfulness!

REPLY
@athenalee

I agree. But I know you’ll continue to inspire with your bubbly cheerfulness!

Jump to this post

LOL Thank you. I wasn’t as disillusioned as I sounded. People often exceed my lowest expectations. Does that make them overachievers? 😂

I admit I’m painfully perky. When my daughter was a sullen teenager, she’d come downstairs in the morning and tell me to at least set my Perky Meter gun down to stun, not to vaporize.

REPLY
Please sign in or register to post a reply.