@johnbishop, @jesfactsmon Hi, I have tried taking the alpha lipoic acid(ALA) in different ways to decrease my upset stomach. I found by eating food first then taking a 600mg capsule with more food decreased the degree of my upset stomach to almost zero. It is much more tolerable. In the future I may try a 300mg capsule twice a day. I saw online a recommendation of 600mg daily helped with neuropathy for diabetics. Although I am not a diabetic, I know 600mg daily provided benefits for me. I also read Acetyl L-Carnitine Amino Acid can provide relief from nerve pain. Has anyone tried the ALCA acid? I was concerned for a vegetarian diet but supplements are available. Apparently some dairy foods contain small amounts of ALCA.
@avmcbellar, Acetyl L-Carnitine is part of the 525 Protocol product that I take (500 mg X 2 daily). Here is an article that provides a little more information on ALC.
@avmcbellar I am not on the protocol but I'd devised something similar based on research (I do not go so high on the B-vitamins). I get my healthy fats from diet as well as 1 tblsp of hempseed oil (which is all fat). I do take carnitine. I take 500 mg per day. I did not notice a decrease in pain that I would specifically attribute to that, but then again, I don't know for sure. I tend to have high triglyerides so more carnitine might help burn fats and lower triglycerides (and when you take ALA it is a fat; the center molecule at the fat burning cycle is carnitine). A small amount of carnitine (500 mg - 1000 mg) should be well tolerated. Carnitine can be metabloized to TMAO which, at higher levels, may not be good. However, that whole issue is complicated by way of some gut bacteria lower TMAO and some raise it. But, like I said, small amounts of carnitine might be helpful - especially if you don't eat much red meat (carnitine is and amino acid - but it is not one of the 20 common amino acids found in proteins - so vegetarians, in paricular might need a supplement. I used nutricost brand from Amazon. I also take turmeric, other flaviniods (especially in green powder supplements) and extra vitamin C, too.
Hi @richman54660 thank you for the information. I know our bodies turn L-Carnitine into Acetyl L-Carnitine. Vegetarians or vegans do have a much lower amounts in their bodies. Since alpha lipoic acid improved my neuropathy and energy level, I am hoping with the combination of the two I will see an even greater improvement. Thanks again. Glad turmeric is helping. Summer time is always more difficult for people with muscle weakness or neuropathy because of the heat. Our bodies can’t deal with the heat because of the misread messages our brain receives. So in the mean time, we have to figure out what to do in order to get through it.
@avmcbellar, Acetyl L-Carnitine is part of the 525 Protocol product that I take (500 mg X 2 daily). Here is an article that provides a little more information on ALC.
@johnbishop thanks John for the article. I also read your feedback on taking Protocal. All the testimonials sound very positive. Unfortunately, I no longer have a facebook account nor do I want one but I did click on the link to order. I found it to be very expensive for a 30 day supply($193.20). For now, I plan to order the ALC to take along with the ALA. If I don’t feel an improvement with my neuropathy then I will consider the protocal. I was wondering if stopping the ALC would stop the benefits. I got the answer through the link you had sent. I agree taking the supplement would be much better than dealing with a medication and its side effects. At least you know 525 Protocal works for you. Thanks for the help!
@johnbishop, @jesfactsmon Hi, I have tried taking the alpha lipoic acid(ALA) in different ways to decrease my upset stomach. I found by eating food first then taking a 600mg capsule with more food decreased the degree of my upset stomach to almost zero. It is much more tolerable. In the future I may try a 300mg capsule twice a day. I saw online a recommendation of 600mg daily helped with neuropathy for diabetics. Although I am not a diabetic, I know 600mg daily provided benefits for me. I also read Acetyl L-Carnitine Amino Acid can provide relief from nerve pain. Has anyone tried the ALCA acid? I was concerned for a vegetarian diet but supplements are available. Apparently some dairy foods contain small amounts of ALCA.
Hi @avmcbellar in addition to RALA Linda and I take a number of things to help boost our mitochondria, which as you probably know, are prevalent throughout your body (literally in the trillions) and are responsible for the body's energy production. One of these is Acetyl L Carnitine (ALC). We take 2 500mg caps together each day with food. We take the RALA 15-30 minutes before this because it is supposed to aid the ALC. What I found out the ALC does is it helps your mitochondria burn fat and create more energy — especially for your muscles and brain. ALC has two main benefits: It shuttles fuel (in the form of fatty acids) to your muscle mitochondria, which ramps up your energy production and can increase endurance, and it also boosts brain power. If you google "r lipoic acid and acetyl l carnitine" you will find a number of articles which discuss the benefits of taking these 2 in conjunction with one another. The reason we take the two 500mg pills together is that I read (and this is purely from memory from a year ago) that your digestive system's enzymatic action will counter it to some extent so you need to take enough to still be effective, hence the 1000mg all at once and not divided into a 500mg dose twice a day. Best, Hank
Hi @avmcbellar in addition to RALA Linda and I take a number of things to help boost our mitochondria, which as you probably know, are prevalent throughout your body (literally in the trillions) and are responsible for the body's energy production. One of these is Acetyl L Carnitine (ALC). We take 2 500mg caps together each day with food. We take the RALA 15-30 minutes before this because it is supposed to aid the ALC. What I found out the ALC does is it helps your mitochondria burn fat and create more energy — especially for your muscles and brain. ALC has two main benefits: It shuttles fuel (in the form of fatty acids) to your muscle mitochondria, which ramps up your energy production and can increase endurance, and it also boosts brain power. If you google "r lipoic acid and acetyl l carnitine" you will find a number of articles which discuss the benefits of taking these 2 in conjunction with one another. The reason we take the two 500mg pills together is that I read (and this is purely from memory from a year ago) that your digestive system's enzymatic action will counter it to some extent so you need to take enough to still be effective, hence the 1000mg all at once and not divided into a 500mg dose twice a day. Best, Hank
@avmcbellar It just hit me that for you to need to take your RALA with food means you would not be able to take it as we do, on an empty stomach 15-30 minutes before eating. But perhaps it's not the big a deal to take the RALA and ALC at the same time with food. Not really sure.
Hi @avmcbellar in addition to RALA Linda and I take a number of things to help boost our mitochondria, which as you probably know, are prevalent throughout your body (literally in the trillions) and are responsible for the body's energy production. One of these is Acetyl L Carnitine (ALC). We take 2 500mg caps together each day with food. We take the RALA 15-30 minutes before this because it is supposed to aid the ALC. What I found out the ALC does is it helps your mitochondria burn fat and create more energy — especially for your muscles and brain. ALC has two main benefits: It shuttles fuel (in the form of fatty acids) to your muscle mitochondria, which ramps up your energy production and can increase endurance, and it also boosts brain power. If you google "r lipoic acid and acetyl l carnitine" you will find a number of articles which discuss the benefits of taking these 2 in conjunction with one another. The reason we take the two 500mg pills together is that I read (and this is purely from memory from a year ago) that your digestive system's enzymatic action will counter it to some extent so you need to take enough to still be effective, hence the 1000mg all at once and not divided into a 500mg dose twice a day. Best, Hank
@jesfactsmon Hi Hank, thank you for the advice. I am grateful for being able to take the ALA for now. Perhaps later on an empty stomach. Before my AVM I had graduated to taking the highest dose available for cayenne pepper capsules. No upset stomach when taken as directed with food. My husband tried but couldn’t tolerate it. So I became determined in finding a way to take the ALA. With the ALC I plan on a total daily dosage of 1000mg. Thanks for the dosage information you and your wife take for the ALA and ALC. It is very helpful. I will figure what will be easier on my stomach. Did you and Linda see a significant difference with the neuropathy pain?
@jesfactsmon Hi Hank, thank you for the advice. I am grateful for being able to take the ALA for now. Perhaps later on an empty stomach. Before my AVM I had graduated to taking the highest dose available for cayenne pepper capsules. No upset stomach when taken as directed with food. My husband tried but couldn’t tolerate it. So I became determined in finding a way to take the ALA. With the ALC I plan on a total daily dosage of 1000mg. Thanks for the dosage information you and your wife take for the ALA and ALC. It is very helpful. I will figure what will be easier on my stomach. Did you and Linda see a significant difference with the neuropathy pain?
I don't think she could know whether it helped or not. I got her and myself (in late 2018) on to so many things at once for boosting the mitochondria. Altogether she takes at least 28 different supplements a day and they change periodically. The mitochondria supplements included ALC, L Carnosine, PQQ, Mito-Q, Niagen and NAC. Actually she was already taking Niagen, but the others were new. We have since quit the PQQ as neither of us noticed much effect from it. The one she got the biggest energy boost from I think was Mito-Q. But as far as pain reduction, hard to say. One supplement she did find helped her neuropathy was Agmatine which I found out about online as a possible benefit for PN. She swore by that for a while, but at some point she started getting a case of hives and suspected the Agmatine due to when she took it and when the reaction occurred. By a total fluke I found some very obscure (not widely discussed) info about Agmatine in one paper that said it can cause a histamine reaction so she dropped it from her regimen. But you might look into it, she really loved it for a while. She also takes benfotiamine for PN but has been unable to say whether she notices any benefit.
I don't think she could know whether it helped or not. I got her and myself (in late 2018) on to so many things at once for boosting the mitochondria. Altogether she takes at least 28 different supplements a day and they change periodically. The mitochondria supplements included ALC, L Carnosine, PQQ, Mito-Q, Niagen and NAC. Actually she was already taking Niagen, but the others were new. We have since quit the PQQ as neither of us noticed much effect from it. The one she got the biggest energy boost from I think was Mito-Q. But as far as pain reduction, hard to say. One supplement she did find helped her neuropathy was Agmatine which I found out about online as a possible benefit for PN. She swore by that for a while, but at some point she started getting a case of hives and suspected the Agmatine due to when she took it and when the reaction occurred. By a total fluke I found some very obscure (not widely discussed) info about Agmatine in one paper that said it can cause a histamine reaction so she dropped it from her regimen. But you might look into it, she really loved it for a while. She also takes benfotiamine for PN but has been unable to say whether she notices any benefit.
Hank, taking many medications and/or supplements at once, certainly makes it much harder to determine what helps with an ailment or gives an allergic reaction. I can understand. I have never had an allergic reaction until last year when I started 2 new supplements at the same time. Since I only take supplements, after my allergic reaction of an itchy rash all over my body, I stopped everything for 2 days then slowly reintroduced supplements until I got the reaction again. It was one of my new supplements which I took before but from a different manufacturer. I never checked to pinpoint the exact culprit.
I will try the combination of ALA and Acetyl L Carnitine first then adjust accordingly from there. You have given me more info to research, thank you!
Hi @lioness, Are you talking about the ALA and Acetyl L Carnitine. Thanks for the confirmation! I did research and found the same results they compliment each other.
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@avmcbellar, Acetyl L-Carnitine is part of the 525 Protocol product that I take (500 mg X 2 daily). Here is an article that provides a little more information on ALC.
The Therapeutic Effects of Acetyl-L-Carnitine on Peripheral Neuropathy: A Review of the Literature: https://www.naturalmedicinejournal.com/journal/2010-08/therapeutic-effects-acetyl-l-carnitine-peripheral-neuropathy-review-literature/
Hi @richman54660 thank you for the information. I know our bodies turn L-Carnitine into Acetyl L-Carnitine. Vegetarians or vegans do have a much lower amounts in their bodies. Since alpha lipoic acid improved my neuropathy and energy level, I am hoping with the combination of the two I will see an even greater improvement. Thanks again. Glad turmeric is helping. Summer time is always more difficult for people with muscle weakness or neuropathy because of the heat. Our bodies can’t deal with the heat because of the misread messages our brain receives. So in the mean time, we have to figure out what to do in order to get through it.
@johnbishop thanks John for the article. I also read your feedback on taking Protocal. All the testimonials sound very positive. Unfortunately, I no longer have a facebook account nor do I want one but I did click on the link to order. I found it to be very expensive for a 30 day supply($193.20). For now, I plan to order the ALC to take along with the ALA. If I don’t feel an improvement with my neuropathy then I will consider the protocal. I was wondering if stopping the ALC would stop the benefits. I got the answer through the link you had sent. I agree taking the supplement would be much better than dealing with a medication and its side effects. At least you know 525 Protocal works for you. Thanks for the help!
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1 ReactionHi @avmcbellar in addition to RALA Linda and I take a number of things to help boost our mitochondria, which as you probably know, are prevalent throughout your body (literally in the trillions) and are responsible for the body's energy production. One of these is Acetyl L Carnitine (ALC). We take 2 500mg caps together each day with food. We take the RALA 15-30 minutes before this because it is supposed to aid the ALC. What I found out the ALC does is it helps your mitochondria burn fat and create more energy — especially for your muscles and brain. ALC has two main benefits: It shuttles fuel (in the form of fatty acids) to your muscle mitochondria, which ramps up your energy production and can increase endurance, and it also boosts brain power. If you google "r lipoic acid and acetyl l carnitine" you will find a number of articles which discuss the benefits of taking these 2 in conjunction with one another. The reason we take the two 500mg pills together is that I read (and this is purely from memory from a year ago) that your digestive system's enzymatic action will counter it to some extent so you need to take enough to still be effective, hence the 1000mg all at once and not divided into a 500mg dose twice a day. Best, Hank
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2 Reactions@avmcbellar It just hit me that for you to need to take your RALA with food means you would not be able to take it as we do, on an empty stomach 15-30 minutes before eating. But perhaps it's not the big a deal to take the RALA and ALC at the same time with food. Not really sure.
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1 Reaction@jesfactsmon Hi Hank, thank you for the advice. I am grateful for being able to take the ALA for now. Perhaps later on an empty stomach. Before my AVM I had graduated to taking the highest dose available for cayenne pepper capsules. No upset stomach when taken as directed with food. My husband tried but couldn’t tolerate it. So I became determined in finding a way to take the ALA. With the ALC I plan on a total daily dosage of 1000mg. Thanks for the dosage information you and your wife take for the ALA and ALC. It is very helpful. I will figure what will be easier on my stomach. Did you and Linda see a significant difference with the neuropathy pain?
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2 ReactionsI don't think she could know whether it helped or not. I got her and myself (in late 2018) on to so many things at once for boosting the mitochondria. Altogether she takes at least 28 different supplements a day and they change periodically. The mitochondria supplements included ALC, L Carnosine, PQQ, Mito-Q, Niagen and NAC. Actually she was already taking Niagen, but the others were new. We have since quit the PQQ as neither of us noticed much effect from it. The one she got the biggest energy boost from I think was Mito-Q. But as far as pain reduction, hard to say. One supplement she did find helped her neuropathy was Agmatine which I found out about online as a possible benefit for PN. She swore by that for a while, but at some point she started getting a case of hives and suspected the Agmatine due to when she took it and when the reaction occurred. By a total fluke I found some very obscure (not widely discussed) info about Agmatine in one paper that said it can cause a histamine reaction so she dropped it from her regimen. But you might look into it, she really loved it for a while. She also takes benfotiamine for PN but has been unable to say whether she notices any benefit.
@jesfactsmon Vitacost where I get my vit min herbs . Has them both together they said in the literature that they compliment each other
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1 ReactionHank, taking many medications and/or supplements at once, certainly makes it much harder to determine what helps with an ailment or gives an allergic reaction. I can understand. I have never had an allergic reaction until last year when I started 2 new supplements at the same time. Since I only take supplements, after my allergic reaction of an itchy rash all over my body, I stopped everything for 2 days then slowly reintroduced supplements until I got the reaction again. It was one of my new supplements which I took before but from a different manufacturer. I never checked to pinpoint the exact culprit.
I will try the combination of ALA and Acetyl L Carnitine first then adjust accordingly from there. You have given me more info to research, thank you!
Hi @lioness, Are you talking about the ALA and Acetyl L Carnitine. Thanks for the confirmation! I did research and found the same results they compliment each other.