PCOS: what causes it? What treatment?

Hi @sehrishagha, welcome. The cause of PCOS is often unknown. Some factors that may play a role, like excess insulin, low-grade inflammation, excess androgen and hereditary factors, are explained in this article by Mayo Clinic. However, it looks like you've tested all those possibilities and results came back normal.
- About Polycystic ovary syndrome (PCOS) https://www.mayoclinic.org/diseases-conditions/pcos/symptoms-causes/syc-20353439

I'd also like to invite fellow members, @kqsr03 @abcdefghi @fishing2990 and @cnc0918 to join this discussion to share their experiences with you.

@sehrishagha, Are you seeking treatment to be able to conceive or to control the acne and unwanted facial hair or both?

Yes, treatment for unwanted hairs and acne. Previously i was using retinoids for acne but their effect was temporary. And also i dont use dairy products they cause severe acne on my face.

I'd like to add my welcome to Mayo Clinic Connect, @sehrishagha. I'd also like to point out a couple Connect discussions you might check out:

- On unwanted facial hair in women https://connect.mayoclinic.org/discussion/facial-hair-on-women/

- On acne treatment https://connect.mayoclinic.org/discussion/acne-medication/

I had treatment in college with isotretinoin (Accutane) and then another round of it in grad school. It was ultimately effective, though I had significant drying in my lips and face. Is this a medication you've tried? If so, how did it go for you?

Yes , i have tried it. It went well for me. But after few months i got acne again. I have tried it 3 times in my life and every time after few months of treatment, i got acne again.

I have pcos my amh before 2 months was 9.18 i take metformin 1550mg per day now my amh is 9.87 what shall I do

@sitraheyru- Good morning and welcome to Mayo Clinic Connect. I am not a doctor and can not answer medical questions. Have you checked with your doctor to see what should be done about your Polycystic ovary syndrome? Having a high-level AMH is indicative of PCOS. Have you had any further treatments?

@sehrishagha - wondering how you are doing?

@sitraheyru - welcome. Nice to meet you.

I do not have PCOS but have friends with it. In their cases, it seemed to be hereditary. Some have regular cycles, others don't, but they were all able to have children (although it took awhile). It seems to be a type of diabetes because they were put on a diabetic diet to help keep their hormones more regular.