Low Dose Naltrexone and Neuropathy

I took LDN in a topical cream prepared by a compounding pharmacy. It caused a nasty rash that has taken weeks to improve. I'm still applying cortisone-10 4 x /day 3 weeks after the rash broke out and it has slowly improved. I suppose this means that taking LDN pill is out of the question - could have an anaphylactic reaction? Anyone have experience with this? Thanks.

I tried a topical LDN cream prepared by a compounding pharmacy and broke out in a nasty rash. Three weeks later, I'm still applying Cortizone10 to my feet, and it is slowly helping the rash. So now, I guess trying LDN in a pill is out of the question - might cause ananaphylactic reaction? Anyone have experience with this?

I’m following up on my previous post from July 19th. At that time I was taking 2.5 mg of low dose naltrexone and it hadn’t helped for my nerve pain. I have worked my way up to 4 mg a day and it still hasn’t helped. I’ve been taking LDN for 5 months now after starting with 0.5 mg. I’ll probably go up to 5 mg and if it still hasn’t helped I’ll stop taking it. I wish I had better news to share, but perhaps 4.5 mg or 5 mg will be the magic number.

@patrick17 Thank you for sharing your experience with LDN. As it sits in my cabinet, I've never actually tried it. Twice now I've been so desperate for something else to help that I considered it, which is why I filled the prescription. Unfortunately, I don't believe that it will help me as I'm already on opiates and not coming off anytime soon. It's discouraging when you hope for something to work and it doesn't. However, the fact that you attempted says a lot and now you can check that one off the list. Perhaps going to 5 will do the trick but if it doesn't thank you so much for being someone who experimented and gave us results. I wish you the best going forward with whatever you find works for you. We must keep trying even when we get exhausted from doing so.
Best to you,
Rachel

@rwinney @patrick17 Hi Guys, we received an order from a pharmacy in NJ about 2 months ago and it too has been "just sitting" on a counter. Linda is a good candidate as she takes no opiates whatsoever. But on any given night she worries so much about getting to sleep that she is afraid it might affect it negatively. I believe her plan is to wait until the weather cools down to start it, as she feels she sleeps better when it's not hot out. I too want to express my thanks to you Patrick, for thinking to update us on your status. Sorry to hear it hasn't helped so far. Wishing for it to start to work at the 5mg dose. Best, Hank

@rwinney Hi Rachel, perhaps you can give LDN a shot sometime in the future. I’ve read that you can take LDN and an opiate as long as you space them apart, but personally I wouldn’t risk it. I sure wouldn’t want to be sent into withdrawal.
Like you, I have tried many therapies and medications for my pain, but not too much has helped. I get the most relief from wearing compression gloves. Without them my pain is much worse. I’ve not really heard that from others with hand pain so I’m not sure why they help me so much. At least the gloves are inexpensive and you don’t have to swallow them like a pill 🙂
All the best to you, also!
Patrick

@patrick17 I have neuropathy through shoulders, arms and hands with the right (dominant side) being worse. My pain flares on it's own. For instance, I can wake up with my hands feeling as though someone stomped on them with workbooks. Or they can feel fine until I use them. For instance the fine motor skills of writing, typing or gripping. They burn, ache, pain, and may have shooting pains. I've never thought of compression gloves but I do understand the theory. Another for instance ...when my right side from shoulder down is burning and paining so awful, I lay on it to apply pressure. Same idea I suppose as the gloves. Do you mind sharing the symptoms and type of pain you experience in your hands? The best natural solution for me is to wrap my mine in either heat or ice depending on the type of pain. Thanks for any input you can offer.
Best,
Rachel

@rwinney. Just read your post about your pain from neck to fingers I have this from fibro and found when I use Topricin on neck where the nerves come from eventually the burning, tingling goes away Have you tried this Rachael?

Hi @lioness! Thanks for your message. I do have Topricin (per your recommendation) and have used to use it on various body parts including my shoulders. It has provided minimal relief.

My shoulders cant handle bedtime because I'm a side sleeper. Every morning I wake in burning pain and aching through my shoulders. I can avoid it if I sleep in my recliner. The other thing are the days when from my shoulder down is pins, needles, and numbness with burning. Who on earth would have ever imagined a body can have multiple pain descriptions.