Low Dose Naltrexone and Neuropathy

Posted by lorirenee1 @lorirenee1, Mon, Jan 6 1:16pm

Hi everyone. Lori Renee here. I have been on Low Dose Naltrexone for about 2 weeks. It may be too soon to post about this medication, but I thought I would post now, and post again, in about 2-4 weeks. Bottom line is that Low Dose Naltrexone has helped considerably with my foot neuropathy. My pain is sometime gone, and usually only reaches a level 5 or so, sometimes. Usually, it is about a 2-3, kind on a low level foot throbbing. Enough to be annoying, but not enough to want to cut my feet off. Without it, I wanted to cut my feet off. Certain problems do remain, so my feet are far from normal still. I put on shoes, and feel like my socks are bunched up, or that there are pebbles in them. It takes me a long time to find a shoe to wear. The balls of my feet still feet like they have been stuck in cement, but not all the time. My toes still feel stuck together, or too widely spread. All crazy sensations of neuropathy. So Low Dose Naltrexone has not taken all the crazies away. However, the pain is so much lower, that I am amazed. I have only used Kratom once in two weeks, which is remarkable. I have no side effects at all from the drug. It is not covered by my Medicare insurance, but is about 35 bucks a month. Not too bad. Anyway, it really is the best pain killer I have tried, other than Kratom. I don't have to taste the vile Kratom, so that is very good. I suggest that everyone give it a try. I read that it helps approximately 25% to 40% of people that try it. The endorphin rush it produces is loaded with pain fighters. Yes, give it a try. I will post again about it, as I use it more. Love to all, Lori Renee

Thanks for this encouraging post. I will look into Naltrerxone for my foot PN.

Liked by lorirenee1, rwinney

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Hey there. I was just thinking about LDN. Glad to hear your good news with it thus far! Im hoping for the best for you and I think you're on to something awesome for your self.

I'm in major pain flares these days and where as my extra strength CBD and THC collectively are not touching enough of my pain, I'm rotating with hydro (still) 4 times a day. It's been over 2 months of experimenting and still no pro.

My goal is to at least reduce final hydro pill of day so then I can take LDN at night. My compounding pharmacy said that it was acceptable to stay on hydro as long as there was the 6 hour rule of no opiods prior to bed time dose. Defeats the process of the LDN to help your brain create it's own natural opiod receptors otherwise. Long term result will hopefully be that opiods are n9 longer needed for pain.

On a side note…I've been researching my use of both medical cannibis and opiods. I'm meeting with my PCP about this next week but honestly I feel I know more about it than he does. The rotating of the 2 approaches has helped pick up slack where the other fails to produce. I will attached a couple of links about mixing opiods amd meducal cannibis. Ultimately the goal is always to ditch the opiods but is totally not possible for me at this time

I will also attached LDN link for anyone unfamiliar.

Wishing you Lori Renee and all my fellow pain sufferers a restful evening.
Rachel

Liked by HankB

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Of course there are definite dangers to mixing opiods and cannibis, similar to mixing alcohol, but I did find this article interesting. .

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This medicine is quite genius if you think about it.

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@terrydclaar

Thanks for this encouraging post. I will look into Naltrerxone for my foot PN.

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@terrydclaar check your private messages here. I wrote you a private message. Lori Renee

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@rwinney

Hey there. I was just thinking about LDN. Glad to hear your good news with it thus far! Im hoping for the best for you and I think you're on to something awesome for your self.

I'm in major pain flares these days and where as my extra strength CBD and THC collectively are not touching enough of my pain, I'm rotating with hydro (still) 4 times a day. It's been over 2 months of experimenting and still no pro.

My goal is to at least reduce final hydro pill of day so then I can take LDN at night. My compounding pharmacy said that it was acceptable to stay on hydro as long as there was the 6 hour rule of no opiods prior to bed time dose. Defeats the process of the LDN to help your brain create it's own natural opiod receptors otherwise. Long term result will hopefully be that opiods are n9 longer needed for pain.

On a side note…I've been researching my use of both medical cannibis and opiods. I'm meeting with my PCP about this next week but honestly I feel I know more about it than he does. The rotating of the 2 approaches has helped pick up slack where the other fails to produce. I will attached a couple of links about mixing opiods amd meducal cannibis. Ultimately the goal is always to ditch the opiods but is totally not possible for me at this time

I will also attached LDN link for anyone unfamiliar.

Wishing you Lori Renee and all my fellow pain sufferers a restful evening.
Rachel

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@rwinney Hi Rachel, From what I know about LDN, when your first take it, there is about a 5 hour amount of time in which your opiod receptors shut down, so that an opiod would not work. Thus, you could not take your hydro at this time, because it would not work for you due to the fact that the receptors are shut down. However, you would be asleep at that time, because it would be in the middle of the night. By the time you wake up in the morning, the receptors would be functioning again, and you would be able to take your hydro and reap the benefits of taking it. So you would be fine during the day, taking the hydro. Depending on when you go to sleep, you would have to stop the hydro 6 hours before, to give the LDN a chance to function. I think this is correct. Anyway, the LDN may really work for you. You would just have to make sure the Hydro and LDN are completely separated. And, of course, you would have to have the luck that you are one of the people that LDN works for. With the severity of your pain, your heavy legs, etc. I really, really, really, would give LDN a try. It has worked well for me, and thanks for your comments about that. Rachel, I really want you to give LDN a try. It is worth a shot. At the worst, it just would not work. I heard it takes at least 2 months or so, to know if it is going to work. Thanks for all the links. I will read them. The very best to you. Living in pain is hell. The LDN is helping me a lot. I am not even going to try the Dorsal Root Stimulator yet. Thank God. No surgery. Anyway, keep us all informed. God bless, and hang tough, lady!!!!! Lori Renee

Liked by rwinney

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@lorirenee1

@rwinney Hi Rachel, From what I know about LDN, when your first take it, there is about a 5 hour amount of time in which your opiod receptors shut down, so that an opiod would not work. Thus, you could not take your hydro at this time, because it would not work for you due to the fact that the receptors are shut down. However, you would be asleep at that time, because it would be in the middle of the night. By the time you wake up in the morning, the receptors would be functioning again, and you would be able to take your hydro and reap the benefits of taking it. So you would be fine during the day, taking the hydro. Depending on when you go to sleep, you would have to stop the hydro 6 hours before, to give the LDN a chance to function. I think this is correct. Anyway, the LDN may really work for you. You would just have to make sure the Hydro and LDN are completely separated. And, of course, you would have to have the luck that you are one of the people that LDN works for. With the severity of your pain, your heavy legs, etc. I really, really, really, would give LDN a try. It has worked well for me, and thanks for your comments about that. Rachel, I really want you to give LDN a try. It is worth a shot. At the worst, it just would not work. I heard it takes at least 2 months or so, to know if it is going to work. Thanks for all the links. I will read them. The very best to you. Living in pain is hell. The LDN is helping me a lot. I am not even going to try the Dorsal Root Stimulator yet. Thank God. No surgery. Anyway, keep us all informed. God bless, and hang tough, lady!!!!! Lori Renee

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Hey there. Thank you for the info. Yes ma'am I have LDN in my cabinet as we speak and will try it soon. My only obstacle is getting through pain at night without hydro. I was hoping extra strength THC would do the trick but it's generally not. Last night I caved after hour and half in bed miserable and took hydro. (I use heat packs all day and sleep with them too, which is best relief, fyi). So that I would not be able to do with out wasting the 1 LDN pill for that day. My PM Dr says if not noticing a positive change after 3 mo then LDN is not right for you. Keep going girl and I'm so happy to hear you are having positive results! 😁

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Hi Lori Renee
Where do you get the LDN from? I understand it comes in 50 mg tablets, and the dose is 4.5 mg per day.
Thanks
Jeff

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@jeffrapp

Hi Lori Renee
Where do you get the LDN from? I understand it comes in 50 mg tablets, and the dose is 4.5 mg per day.
Thanks
Jeff

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@jeffrapp Hi Jeff, The 50 mg pill is the regular Naltrexone. It is not the Low Dose Naltrexone. That is not the right pill. You must find a pharmacy that will make this Low Dose Naltrexone, 4.5 mg. pill for you. Furthermore, you generally start out at about 3.0 mg., and have to work up to 4.5 mg. after 3 days. It is called a "compounding pharmacy" that you have to find. The pharmacist, literally, makes the LDN special order, just for you. You cannot just cut up the 50 mg. regular Naltrexone pills. You will not get the dosage right. Good luck, and give it a try. Lori

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@rwinney

Hey there. Thank you for the info. Yes ma'am I have LDN in my cabinet as we speak and will try it soon. My only obstacle is getting through pain at night without hydro. I was hoping extra strength THC would do the trick but it's generally not. Last night I caved after hour and half in bed miserable and took hydro. (I use heat packs all day and sleep with them too, which is best relief, fyi). So that I would not be able to do with out wasting the 1 LDN pill for that day. My PM Dr says if not noticing a positive change after 3 mo then LDN is not right for you. Keep going girl and I'm so happy to hear you are having positive results! 😁

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@rwinney I have pain at nite also. Not severe, but not good. I have a few inhales of marijuana. Very light inhales. I hate being stoned. That and the LDN seem to do the trick for the evening. I do not remember; do you use marijuana? It does seem to be ok at night in terms of not feeling too much pain. If the LDN worked for you, it might be even enough. You never know. To clarify, you are saying that the night LDN dose you would take, would interfere with the Hydro from working? The LDN would close the receptor sights, and the hydro could no longer attach to them. I am sleepy. I hope I am making sense. Have marijuana in me as I write. I hope I am making some sense!!!!! Lori

Liked by rwinney

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@lorirenee1

@rwinney I have pain at nite also. Not severe, but not good. I have a few inhales of marijuana. Very light inhales. I hate being stoned. That and the LDN seem to do the trick for the evening. I do not remember; do you use marijuana? It does seem to be ok at night in terms of not feeling too much pain. If the LDN worked for you, it might be even enough. You never know. To clarify, you are saying that the night LDN dose you would take, would interfere with the Hydro from working? The LDN would close the receptor sights, and the hydro could no longer attach to them. I am sleepy. I hope I am making sense. Have marijuana in me as I write. I hope I am making some sense!!!!! Lori

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Correct. Need that 6 hour seperation.

Liked by lorirenee1

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@lorirenee1

@terrydclaar check your private messages here. I wrote you a private message. Lori Renee

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Not sure how to access private messages. Can you help me, thanks, Terry

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