FOLFIRINOX chemo and blood blisters in mouth

Posted by lbern @lbern, Feb 14, 2019

I am receiving folfirinox chemo and developing clumps of blood blisters in my mouth. Some weeks I get large ones, other times they are tiny. They engorge with blood, pop, then remain as a mass of necrotic tissue. I am on blood thinners so doctors are reluctant to excise the mass. I am wondering if anyone has experienced blood blisters in mouth, and what possible triggers might be. I have a theory the big ones develop after I eat an acidic food, but don't know if there's any truth behind that. Also wondering how you treated them, I am treated with chlorhexidine 0.12 % mouth/throat solution, but the mass of tissue remains in my mouth. There also is some discussion on if it's getting infected or not-I have redness on skin outside of cheek on side that has the necrotic blisters , swelling, and warmth.
Any ideas on how I can prevent them/ treat them are much appreciated. (I do not bite my cheek or eat pointy hard food) -thanks

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lbern | @lbern | Feb 20, 2019

I get chemo every other week. I started Nov 13 and haven't missed one. I had a CT scan on Jan 4 which had some indefinite result so had an MRI on Jan 18. I've had one tumor marker blood test 2 weeks ago to compare to one from approx Nov 7. I need a special tumor marker test that they send to Mayo for analysis since my tumor marker is too high for our clinic's test to analyze. I wonder if my chemo stops working, how long it would take to know it and switch to another regime.....