1. < Kidney & Bladder

concerned over rising creatinine level.

Posted by rans @rans, Dec 11, 2018

Labs showed level increased from 1.5 to 1.7. All my other numbers were ok. GP took me off my BP ( lisinopril ) med for one week and then retest.( pending

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sissieann | @sissieann | Dec 12, 2018
In reply to @kamama94 "@Martin Jensen and everyone wondering about Lisinopril: I've read and been told that ACE-inhibitors like Lisinopril..." + (show)
@kamama94

@martin Jensen and everyone wondering about Lisinopril:

I've read and been told that ACE-inhibitors like Lisinopril can protect the kidney from renal hypertension (relieving glomerular pressure by lowering blood pressure, especially in diabetics.) But it also can decrease GFR because it blocks a protective mechanism which occurs in the kidney to maintain GFR.

So it seems to be a tossup - protect the kidney and improve function by controlling blood pressure vs protect the kidney's GFR status which MIGHT be impaired by the blood pressure med.

This is not medical advice or diagnosis, just my opinion based on my nurse's training as well as on fairly recent research done on my own.

I'm guessing my neph and primary both told me to stay on Lisinopril for now because they believe the benefits of lowering my blood pressure outweigh the risks of lowering GFR, especially since my GFR is above 30.

I'm also guessing that if my GFR declines too much we will have to seek alternatives.

Once again, these are just my own guesses and opinions based on a small amount of research.

Here are some websites with more information on the subject:
https://www.mdedge.com/clinicianreviews/article/134719/nephrology/when-discontinue-raas-therapy-ckd-patients
tmedweb.tulane.edu/pharmwiki/doku.php/ace_inhibitor_pharmacology
https://universityhealthnews.com/topics/heart-health-topics/3-ace-inhibitor-side-effects-should-you-seek-out-alternatives/

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Thxs for checking! Since I’ve been off lis my BP has been elevated along with, feels like vent fib, but doesn’t show on EKG..,
I’ll go back and look at past labs to compare..I see my nep 12/26 and we will hv a chat...lol
Thanks to all for input! So valuable....truly appreciate everyone!

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sissieann | @sissieann | Dec 12, 2018
In reply to @marvinjsturing "I am on a low dosage of lisinipril - 2.5 mg a day. My nephrologist said..." + (show)
@marvinjsturing

I am on a low dosage of lisinipril - 2.5 mg a day. My nephrologist said she prescribed it to slow down the deterioration of my kdneys.

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Wow...your post got me thinking...BP out of control is bad on kidneys...so is my still high BP, now with “flutters”, causing MORE damage to my kidneys than taking lisp...which BTW kept my BP and heart very steady....interesting! Thanks for the post...I’ll let u know what my nep says after Christmas.

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rans | @rans | Dec 19, 2018

Retested after being off BP meds for a week. Creatinine dropped 1 point to 1.6. GP says that is not a real change from 1.7. ultrasound tomorrow.

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kamama94 | @kamama94 | Dec 19, 2018

@rans Fingers crossed here also. I think I'd like a drop from .7 to .6 on the theory that every little bit helps even if it IS only a little bit. Keep us posted.

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1 reply
rans | @rans | Jan 3, 2019
In reply to @kamama94 "@rans Fingers crossed here also. I think I'd like a drop from .7 to .6 on..." + (show)
@kamama94

@rans Fingers crossed here also. I think I'd like a drop from .7 to .6 on the theory that every little bit helps even if it IS only a little bit. Keep us posted.

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Results of ultra sound were inconclusive. I'm being referred to a kidney clinic. GP just doesn't seem very knowledgeable on the subject, maybe it's time for some self diagnosis. I'm leaning towards urine retention because of BPH.

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1 reply
rans | @rans | Jan 3, 2019
In reply to @trishanna "@rans Fingers crossed!!" + (show)
@trishanna

@rans Fingers crossed!!

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Thanks for the crossed fingers.

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Moderator
Colleen Young, Connect Director | @colleenyoung | Jan 6, 2019
In reply to @rans "Results of ultra sound were inconclusive. I'm being referred to a kidney clinic. GP just doesn't..." + (show)
@rans

Results of ultra sound were inconclusive. I'm being referred to a kidney clinic. GP just doesn't seem very knowledgeable on the subject, maybe it's time for some self diagnosis. I'm leaning towards urine retention because of BPH.

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It is a wise physician who recognizes his/her lack of knowledge in a particular area and refers you to a specialist. Please let us know what you find our at your appointment with the kidney clinic.

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1 reply
rans | @rans | Jan 13, 2019
In reply to @colleenyoung "It is a wise physician who recognizes his/her lack of knowledge in a particular area and..." + (show)
@colleenyoung

It is a wise physician who recognizes his/her lack of knowledge in a particular area and refers you to a specialist. Please let us know what you find our at your appointment with the kidney clinic.

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Will do.

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glennpartridge | @glennpartridge | Jan 18, 2019
In reply to @trishanna "Things to be concerned about keep popping up, don't they. I, too, take Lisinopril. Shall check..." + (show)
@trishanna

Things to be concerned about keep popping up, don't they. I, too, take Lisinopril. Shall check this out, too.

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@ trishanna Speak to your Neph about ramipril. It is less harsh than Lisinopril'

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