Forteo vs. Tymlos: Which did you choose?

Interesting, not bad results! 60.7% is an ok percentage if you/we fall in that percentage.I wonder what the results will be at 48 months of treatment and later. I have heard that TYMLOS continues to work for a time ( don’t know how long) after the patient finishes 2 years of injections. Perhaps results can be better. I’m hopeful.

My understanding is that both Forteo and Tymlos, after being taken for the allowed 2 years, are usually followed by some one of the bone maintenance drugs, such a bisphosphonate, to maintain the bone gain.
BTW, You asked about side effects. Eight weeks after I started, my doctored ordered tests for calcium, creatine, and PTH to assess whether the injections might be having an adverse effect; those tests were for me all normal. PTH- parathyroid hormone (often described as a sort of calcium thermostat) when elevated can cause your body to think that you do not have enough calcium resulting in calcium being pulled from bones-- so blood or urine will show excess calcium. Forteo and Tymlos are some type of parathyroid, but if they work as intended, strengthen rather than weaken bones. You might notice a sense of rapid heart rate when you first do the injection, but it goes away quickly; I had it a few times during the first two weeks. Not at all a big deal to me, because I had read that PTH increases heart rate & figured it was just my body acclimating. As I said, I was anxious at the start, but have found that the self injections and the drug were not such a big deal. I sure hope it works to strengthen our spines.

You have to go every day to the doctor for a shot?

No, you don't have to. You keep the preloaded injections at home. You learn how to use them from a nurse and inject yourself daily. It's a pre-loaded "syringe", for lack of a better word. My understanding is, it's similar to a preloaded insulin injection. I haven't started using it yet, in a week or so I hope to. As soon as it can be arranged I'm going forward.

I give my injection at night, seems easier than as part of a morning rush. And my bedtime is more consistent. But for Forteo, which is similar to Tymlos, this study showed a significantly greater response in the lumbar spine when injections were in the morning. Has anyone heard more about this?
"A 12-month morning teriparatide (TPTD) administration resulted in a larger increase in the lumbar spine bone mineral density (BMD) than the evening application. The results indicate that the response of bone cells to teriparatide treatment depends on dosing time." "After 12 months, the lumbar spine BMD grew markedly (p 

Hi @betterbones,

I merged your post about "Morning better results for Forteo/Tymlos time of injection-" with this discussion, so that you could reconnect with the members who are part of this conversation.
Here's a link to the article that you've mentioned regarding timing of Forteo injections: https://www.ncbi.nlm.nih.gov/pubmed/22426952

Thank you, interesting and important information!

I am just joining this group- trying to decide between Forteo and Tymlos. Tymlos has not been on the market long whereas Forteo has been on for 16 years. Forteo has to be refrigerated (inconvenient) and Tymlos doesn't. I'm a little worried about taking a brand new drug. Can anyone offer some perspective? I'm 56 years old with OP in spine -3.3, neck -2.3. Thank you so much.

I'm 56 with Osteoporosis and am trying to choose between Forteo and Tymlos for injectible. Forteo has been around so much longer (16 years vs. 1 1/2 for Tymlos) but I don't like the inconvenience of having to refrigerate it. Can anyone offer a perspective? Many thanks!

I replied on another thread. More information-- even once you receive insurance approval. To use the drug, you will need to have a training session. I think an in person one is good because the trainer can see your body type, and give you tips accordingly.